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Giant Cell Arteritis (Horton Disease)

A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)
Also Known As:
Horton Disease; Juvenile Temporal Arteritis; Arteritis, Temporal; Cranial Arteritis; Arteritis, Giant Cell, Horton; Arteritis, Giant Cell, Horton's; Giant Cell Aortic Arteritis; Giant Cell Aortitis; Giant Cell Aortitis, Horton's; Giant Cell Arteritis, Horton; Horton's Disease; Horton's Giant Cell Arteritis; Aortitides, Giant Cell; Arteritides, Cranial; Arteritides, Giant Cell; Arteritides, Juvenile Temporal; Arteritides, Temporal; Arteritis, Cranial; Arteritis, Giant Cell; Arteritis, Juvenile Temporal; Cranial Arteritides; Giant Cell Aortitides; Giant Cell Arteritides; Hortons Disease; Juvenile Temporal Arteritides; Temporal Arteritides; Temporal Arteritides, Juvenile; Temporal Arteritis, Juvenile; Aortic Arteritis, Giant Cell; Aortitis, Giant Cell; Horton Giant Cell Arteritis; Temporal Arteritis
Networked: 1117 relevant articles (43 outcomes, 77 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Polymyalgia Rheumatica (Rhizomelic Pseudopolyarthritis)
2. Takayasu Arteritis (Arteritis, Takayasu's)
3. Giant Cell Arteritis (Horton Disease)
4. Vasculitis (Vasculitides)
5. Aortitis

Experts

1. Salvarani, Carlo: 24 articles (09/2015 - 11/2002)
2. Boiardi, Luigi: 17 articles (09/2015 - 11/2002)
3. Cid, Maria C: 17 articles (02/2015 - 05/2002)
4. Pipitone, Nicolò: 15 articles (10/2014 - 04/2005)
5. Hernández-Rodríguez, José: 13 articles (02/2015 - 05/2003)
6. Weyand, Cornelia M: 13 articles (01/2011 - 01/2002)
7. García-Martínez, Ana: 12 articles (02/2015 - 05/2003)
8. Gonzalez-Gay, Miguel A: 12 articles (01/2010 - 09/2003)
9. Prieto-González, Sergio: 11 articles (02/2015 - 06/2010)
10. Goronzy, Jörg J: 11 articles (01/2011 - 01/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Giant Cell Arteritis:
1. Adrenal Cortex Hormones (Corticosteroids)IBA
2. Prednisone (Sone)FDA LinkGeneric
3. tocilizumabFDA Link
4. SteroidsIBA
5. glucuronyl glucosamine glycan sulfate (Vessel)IBA
6. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
7. GlucocorticoidsIBA
8. infliximab (Remicade)FDA Link
9. C-Reactive ProteinIBA
10. Methotrexate (Mexate)FDA LinkGeneric

Therapies and Procedures

1. Cardiopulmonary Resuscitation (CPR)
2. Aftercare (After-Treatment)
3. Injections
4. Oral Administration
5. Hysterectomy