|1.||Taste Disorders (Taste Disorder)
|3.||Chronic Kidney Failure (Chronic Renal Failure)
|1.||Sakagami, Masafumi: 10 articles (09/2015 - 03/2002)|
|2.||Ikeda, Minoru: 7 articles (08/2014 - 01/2002)|
|3.||Tomita, Hiroshi: 6 articles (10/2009 - 01/2002)|
|4.||Inokuchi, Akira: 5 articles (08/2014 - 11/2005)|
|5.||Landis, Basile N: 5 articles (01/2014 - 07/2006)|
|6.||Lawless, Harry T: 5 articles (06/2008 - 01/2004)|
|7.||Takeda, Noriaki: 4 articles (08/2014 - 11/2005)|
|8.||Kurono, Yuichi: 4 articles (08/2014 - 11/2005)|
|9.||Aiba, Tsunemasa: 4 articles (08/2014 - 11/2005)|
|10.||Ikui, Akihiro: 4 articles (10/2009 - 01/2002)|
01/01/2014 - "We found very low quality evidence that was insufficient to conclude on the role of zinc supplements to improve taste perception by patients, however we found moderate quality evidence that zinc supplements improve overall taste improvement in patients with zinc deficiency/idiopathic taste disorders. "
01/01/2010 - "This clinical observation, together with recent findings on significant improvement of taste disorders after zinc treatments for other causes, opens again the question of what extent zinc deficiency plays a role in PTD."
01/01/2013 - "In conclusion, administration of a zinc agent is effective for patients with taste disorders, provided selection of appropriate patients is performed, and that proper examination and evaluation are conducted. "
11/01/2005 - "Administration of zinc is the main treatment for taste disorders in Japan. "
01/01/2013 - "Taste disorders caused by depression may not be cured by zinc supplementation due in part to the fact that the symptom is based on a mental issue, and due in part to the conservative responding bias generated by the depression itself, which may inhibit accurate and precise diagnosis of the disorder. "
|2.||polaprezinc (Z 103)IBA
01/01/2012 - "In this review, we primarily make reference to our own data on the pharmacological action of polaprezinc on taste disorders and introduce recent research on the effects of polaprezinc in treating other diseases."
01/01/2012 - "The pharmacological action of polaprezinc, however, on taste disorders remains unclear. "
04/01/2011 - "[Orally administered polaprezinc significantly improves taste disorders in ovarian cancer patient undergoing chemotherapy]."
10/01/2009 - "A zinc-containing compound, Polaprezinc, is effective for patients with taste disorders: randomized, double-blind, placebo-controlled, multi-center study."
04/01/2011 - "Orally disintegrating tablets of polaprezinc were then administered to the patient, after which the subjective symptom of taste disorder improved. "
|3.||picolinic acid (chromium picolinate)IBA
07/01/1995 - "[Therapeutic efficacy of zinc picolinate in patients with taste disorders]."
01/01/2002 - "Double-blind, placebo-controlled trial of zinc picolinate for taste disorders."
07/01/1995 - "4. We conclude that the administration of zinc picolinate is effective for patients with zinc-deficient and idiopathic taste disorders."
07/01/1995 - "We studied the therapeutic efficacy of zinc picolinate in patients with zinc-deficient and idiopathic taste disorders. "
01/01/2002 - "A total of 73 patients with an idiopathic zinc-deficiency taste disorder completed a double-blind, placebo-controlled trial of the efficacy of zinc picolinate. "
|6.||Histamine (Histamine Dihydrochloride)FDA Link
|7.||2-benzyl-3-formylpropanoic acid (BFP)IBA
|8.||gluconic acid (gluconate)FDA LinkGeneric
01/01/1991 - "The therapeutic efficacy of orally given zinc gluconate on taste disorder was investigated by a double-blind study in 98 patients with a chief complaint of this disease. "
01/01/1991 - "A double-blind study of the therapeutic efficacy of zinc gluconate on taste disorder."
01/01/1991 - "Although no significant difference was detected between the two groups in overall efficacy, a significant superiority of zinc gluconate to placebo was observed in patients with idiopathic and zinc-deficient taste disorder. "
|9.||Metronidazole (Metric)FDA LinkGeneric
11/01/2000 - "Common adverse effects of metronidazole include nausea and a metallic taste. "
01/01/2009 - "Metronidazole caused metallic taste, nausea and vomiting. "
01/01/2010 - "However, tinidazole has a more favorable side effect profile than oral metronidazole notably with better gastrointestinal tolerability and less metallic taste. "
09/01/2006 - "Patients in the albendazole group had fewer side-effects while 43.3% of the metronidazole group experienced a metallic taste and 35.0% experienced loss of appetite. "
11/01/1989 - "Side effects from metronidazole (black tongue, dark urine, paraesthesia, metallic taste, epigastric pain, skin reactions, nausea) were reported by over 80% of the patients at any time of the study. "
09/01/2009 - "Taking into account the results of this study an otosurgeon might be able to anticipate the potential risk for the CTN by judging the AHD-status intraoperatively and - therefore - reduce taste disorders postoperatively. "
09/01/2009 - "The aim of this study was to develop a clinical classification of the intraoperatively visible course of the CTN and to demonstrate a possible correlation of its anatomic course with the prevalence of actual postoperative taste disorders. "
12/01/2012 - "In conclusion, even after minor CTN manipulation the rate of postoperative taste disorders or tongue symptoms after stapes surgery is high. "
09/30/2015 - "In medical practice, the chorda tympani nerve (CTN) is injured in some patients during middle-ear surgery, and results in tongue numbness and taste disorder. "
03/01/2006 - "In unilateral section of CTN, 19/32 (59.4%) complained of taste disorder and 11/32 (34.4%) tongue numbness. "
06/01/2012 - "Fifteen patients from the initial trial, who reported taste disorders after tonsillectomy, were contacted again for this long-term follow-up. "
10/01/2010 - "The aim of the study was to provide a symptom-based follow-up after tonsillectomy to assess postoperative taste disorders. "
06/01/2012 - "Eight percent of patients reported subjective taste disorders 6 months after tonsillectomy. "
06/01/2012 - "Taste disorders after tonsillectomy: a long-term follow-up."
10/01/2010 - "Thirty-two percent (n = 60) of patients reported taste disorders after tonsillectomy 2 weeks postoperatively and 15 patients (8%) at 6-month follow-up. "
09/01/2013 - "The aim of this study was, therefore, to elicit the risk of taste disorders following cochlear implantation surgery involving a mastoidectomy and a posterior tympanotomy approach. "
12/01/2010 - "The objective of this study was to investigate the occurrence of vestibular receptor deficiency and taste disorders after bilateral cochlear implantation in postlingually deafened patients and to find out whether the risk for these complications is higher for the second implantation. "
12/01/2010 - "The occurrence of unilateral and/or bilateral vestibular dysfunction and the potential risk of taste disorder should be included in the risk counseling before bilateral cochlear implantation to increase patients' and medicolegal safety in the decision-making process."
12/01/2010 - "Specific testing showed in one case (5%) a unilateral taste disorder after ipsilateral cochlear implantation. "
12/01/2010 - "Vestibular and taste disorders after bilateral cochlear implantation."
|3.||Drug Therapy (Chemotherapy)
12/01/2012 - "Qualitative changes, for example, metallic taste, are frequent but cannot be attributed to specific chemotherapy regimens. "
04/01/2011 - "To understand how the taste disorder was caused by chemotherapy objectively, taste examinations were conducted for the patient in our department. "
04/01/2011 - "She greatly complained of taste disorders after four cycles(of every other week administration) of TC chemotherapy. "
02/01/2015 - "Although metallic taste is a frequent side effect of chemotherapy and a much discussed topic on cancer patient forums, literature regarding metallic taste among chemotherapy treated cancer patients is scarce. "
02/01/2015 - "Prevalence of metallic taste ranged from 9.7% to 78% among patients with various cancers, chemotherapy treatments, and treatment phases. "
07/01/2006 - "Smell and taste disorders are among the side effects of chemo- and radiotherapy. "
05/01/1970 - "[Taste disorders following radiotherapy in the head-neck region]."
09/01/2009 - "In evaluating the effect of cepharanthin on xerostomia and taste disorder in 40 patients undergoing radiotherapy for head and neck cancer, we administered cepharanthin intravenously during chemoradiotherapy to 22 patients, with 18 others as a control group. "