Takayasu Arteritis (Arteritis, Takayasu's)

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484 relevant articles (15 outcomes, 23 trials/studies) found for this Disease

Description: A chronic inflammatory process that affects the AORTA and its primary branches, such as the brachiocephalic artery (BRACHIOCEPHALIC TRUNK) and CAROTID ARTERIES. It results in progressive arterial stenosis, occlusion, and aneurysm formation. The pulse in the arm is hard to detect. Patients with aortitis syndrome often exhibit retinopathy.

Also Known As:

Arteritis, Takayasu's; Takayasu Syndrome; Takayasu's Arteritis; Arteritis, Takayasu; Arteritis, Takayasus; Syndrome, Aortitis; Takayasus Arteritis; Aortitis Syndrome; Pulseless Disease

Relationship Network

Disease Context: Research Results

Cardiovascular Diseases: 18525

Vascular Diseases: 7184

Vasculitis: 6337

Arteritis: 812

Takayasu Arteritis: 484

Arteritis: 812

Takayasu Arteritis: 484

Aortic Diseases: 219

Aortic Arch Syndromes: 7

Takayasu Arteritis: 484

Skin and Connective Tissue Diseases

Skin Diseases: 5944

Vascular Skin Diseases: 2

Takayasu Arteritis: 484

Related Diseases

1.	Renovascular Hypertension (Goldblatt Syndrome)
2.	Aneurysm (Aneurysms)
3.	Hypertension (High Blood Pressure)
4.	Renal Artery Obstruction (Renal Artery Stenosis)
5.	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome)

Experts

1.	Nityanand, Soniya: 5 articles (08/2007 - 09/2003)
2.	Reyes, Pedro A: 4 articles (10/2008 - 01/2005)
3.	Tripathy, Naresh Kumar: 4 articles (07/2006 - 09/2003)
4.	Nityanand, S: 4 articles (11/2004 - 04/2001)
5.	Vargas-Alarcón, Gilberto: 3 articles (10/2008 - 01/2005)
6.	Chauhan, Sunil Kumar: 3 articles (08/2007 - 02/2006)
7.	Tripathy, N K: 3 articles (01/2004 - 04/2001)
8.	Sinha, N: 3 articles (01/2004 - 04/2001)
9.	Alvarez-León, Edith: 2 articles (10/2008 - 05/2007)
10.	Cicero-Sabido, Raúl: 2 articles (10/2008 - 05/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Takayasu Arteritis:

1.	Methotrexate (Mexate)FDA LinkGeneric 10/01/1989 - "This is the first case report of Takayasu's arteritis treated successfully with low-dose pulse methotrexate." 01/01/1994 - "At present, methotrexate appears to be an effective steroid-sparing agent in the treatment of active Takayasu's arteritis" 11/01/2007 - "The two patients who stopped methotrexate treatment died from complications of Takayasu's arteritis" 05/01/1998 - "Low-dose methotrexate as a steroid-sparing agent in a child with Takayasu's arteritis." 04/01/1994 - "Treatment of glucocorticoid-resistant or relapsing Takayasu arteritis with methotrexate." Order ALL the reference details at left...
2.	infliximab (Remicade)FDA Link 06/01/2007 - "CONCLUSIONS: Infliximab might be an effective and safe alternative for patients with Takayasu arteritis." 06/01/2007 - "Infliximab in Takayasu arteritis: a safe alternative?" 08/01/2005 - "Two Takayasu arteritis patients successfully treated with infliximab: a potential disease-modifying agent?" 08/01/2005 - "Infliximab-responsive uveitis and vasculitis in a patient with Takayasu arteritis." 01/01/2006 - "Infliximab is effective for Takayasu arteritis refractory to glucocorticoid and methotrexate." Order ALL the reference details at left...
3.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/01/2008 - "Anti-tumor necrosis factor agents can have a role in the treatment of Takayasu's arteritis; further controlled studies are required." 09/01/2008 - "Four children with Takayasu's arteritis were treated with tumor necrosis factor antagonists because of disease relapse during conventional therapy or as a first-line agent" 09/01/2008 - "Treatment of Takayasu's arteritis with tumor necrosis factor antagonists." 07/01/2004 - "Anti-tumor necrosis factor therapy in patients with difficult to treat Takayasu arteritis." 07/01/2004 - "OBJECTIVE: Granulomatous inflammation is a typical feature of Takayasu arteritis (TA), and tumor necrosis factor (TNF) is important in the formation of granulomas" Order ALL the reference details at left...
4.	Prednisolone (Predate)FDA LinkGeneric 11/01/2007 - "She had aortitis syndrome which had been treated with oral prednisolone for 6 months" 05/01/1995 - "Although there were no symptoms or signs of systemic arterial lesions, the initial diagnosis was aortitis syndrome with pulmonary arterial involvement, and prednisolone therapy was started (60 mg/day)" 08/01/1992 - "One of the characteristic problems in Takayasu's arteritis is the necessity for prednisolone administration in some patients preoperatively or postoperatively, or both" 10/01/1991 - "From the above findings, she was diagnosed aortitis syndrome, and treatment was begun with prednisolone" 05/01/1990 - "A 35 mg daily dose of prednisolone for aortitis syndrome was initiated, and the dose was gradually reduced" Order ALL the reference details at left...
5.	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 11/01/2007 - "This case shows that ultrasonography in the cervical region and combined 18F-FDG PET with CT may be useful in the diagnosis and evaluation of Takayasu arteritis" 06/01/2006 - "18FDG PET: a new criterion for disease activity in Takayasu arteritis]" 01/01/2006 - "18F]fluorodeoxyglucose positron emission tomography is a useful tool to diagnose the early stage of Takayasu's arteritis and to evaluate the activity of the disease." 05/01/2004 - "The role of 18F-FDG PET in characterising disease activity in Takayasu arteritis." 01/01/1999 - "We report a unique case of early-phase Takayasu arteritis in which the vessels demonstrated accumulation of [18F]fluorodeoxyglucose (FDG) on PET scanning" Order ALL the reference details at left...
6.	Adrenal Cortex Hormones (Corticosteroids)IBA 04/01/1996 - "She was diagnosed as having aortitis syndrome twenty years ago, and has been treated with systemic corticosteroids" 03/01/1985 - "Takayasu arteritis is more common than previously suspected in North America, is not restricted to any one racial group, and is readily treatable with corticosteroids and surgical vascular reconstruction." 02/01/1984 - "Takayasu's arteritis: reversal of pulse deficit after early treatment with corticosteroids." 05/01/2003 - "A patient with Takayasu's arteritis treated with corticosteroids who developed primary biliary cirrhosis." 10/01/1998 - "We present a case of 'subclavian steal syndrome' secondary to Takayasu arteritis, in a 32-year-old, Japanese woman, whose clinical manifestations result from severe ocular and brain ischemia, refractory to high dose systemic corticosteroids" Order ALL the reference details at left...
7.	Cyclosporine (Ciclosporin)FDA LinkGeneric 07/01/2004 - "We describe a case of PG that was associated with Takayasu's arteritis who was successfully treated with systemic cyclosporin" 06/07/1999 - "Treatment of glucocorticoid-dependent Takayasu's arteritis with cyclosporin." 08/01/1999 - "A 33-year-old caucasian woman with pyoderma gangrenosum associated with Takayasu's arteritis responded to treatment with cyclosporin" 08/01/1999 - "Pyoderma gangrenosum associated with Takayasu's arteritis responding to cyclosporin." 11/01/1991 - "Cyclosporine treatment of severe recalcitrant pyoderma gangrenosum in a patient with Takayasu's arteritis." Order ALL the reference details at left...
8.	HLA-DR Antigens (HLA-DR)IBA 04/01/2000 - "Endothelial cells (ECs) of most vasa vasorum expressed HLA-DR. The number of vasa vasorum around which inflammatory infiltrating cells were observed in vasculo-Behçet disease was significantly greater than in inflammatory aneurysms and Takayasu's arteritis (P < 0.001)" 03/01/1992 - "Sixty-four patients with Takayasu arteritis and 317 healthy individuals in the Japanese population were examined for HLA-A, -B and -C alleles by serological typing and for HLA-DR, DQ and DP alleles by DNA typing using PCR/SSOP analysis" 01/01/1992 - "To investigate genetic factors involved in the pathogenesis of Takayasu arteritis, patients in the Japanese population were examined for HLA-A, -B, and -C alleles by serological typing and for HLA-DR, DQ, and DP alleles by DNA typing using polymerase chain reaction (PCR)/sequence-specific oligonucleotide probe (SSOP) analysis" 01/01/1992 - "This finding suggests that the disease susceptibility gene of Takayasu arteritis is located between the HLA-B locus and HLA-DR, DQ loci." 03/01/1999 - "The present patient had human leukocyte antigen (HLA)-B 52, which is reported to be related to the aortitis syndrome, as well as HLA-DR 4, which is possibly related to IgA nephropathy, suggesting that HLA status may be involved in the pathogenesis of both diseases." Order ALL the reference details at left...
9.	mycophenolate mofetil (Cellcept)FDA Link 11/01/2007 - "Mycophenolate mofetil reduces disease activity and steroid dosage in Takayasu arteritis." 03/02/1999 - "OBJECTIVE: To evaluate the effect of mycophenolate mofetil in patients with severe Takayasu arteritis" 03/02/1999 - "Mycophenolate mofetil for the treatment of Takayasu arteritis: report of three cases." 11/01/2007 - "Mycophenolate mofetil (MMF) has recently been reported as a useful alternative immunosuppressive drug in autoimmune diseases including in Takayasu arteritis (TA)" 03/02/1999 - "CONCLUSIONS: Mycophenolate mofetil may be an alternative to steroids and cytotoxic agents in patients with Takayasu arteritis" Order ALL the reference details at left...
10.	Azathioprine (Imuran)FDA LinkGeneric 08/01/2003 - "OBJECTIVE: To evaluate the role of an immunosuppressive regimen consisting of azathioprine and prednisolone on the clinical, immunological, and angiographic outcome in patients with active Takayasu's arteritis (TA)" 06/01/2007 - "MATERIALS AND METHODS: We used infliximab at an initial dose of 3 mg/kg i.v. at weeks 0, 2, 6, and 8 thereafter in combination with methotrexate or azathioprine, to treat four patients with Takayasu arteritis" 01/01/2005 - "RECENT FINDINGS: Immunosuppressive agents including methotrexate, mycophenolate mofetil, and azathioprine added to corticosteroids can bring Takayasu arteritis into remission in many patients" Order ALL the reference details at left...

Therapies and Procedures

1.	Stents 03/01/2004 - "We suggest that surgical treatment is beneficial for in-stent restenosis in patient with Takayasu arteritis." 12/01/2000 - "Our series demonstrates the safety and efficacy of stent deployment in stenotic lesions of the aorta in Takayasu arteritis and proves that the results are superior to plain balloon aortoplasty alone" 01/01/2006 - "Unprotected left main stent placement in a patient with Takayasu's arteritis: an unusual solution for an unusual disease." 03/01/2004 - "Axillo-axillary bypass for in-stent restenosis in Takayasu arteritis." 12/01/2002 - "PURPOSE: To illustrate the possible peri- and postprocedural complications of stent treatment for Takayasu arteritis and suggest ways of reducing these risks" Order ALL the reference details at left...
2.	Balloon Angioplasty (Angioplasty, Transluminal) 06/01/2008 - "Takayasu's arteritis treated by percutaneous transluminal angioplasty with stenting in the descending aorta." 08/31/2000 - "A follow-up study of balloon angioplasty and de-novo stenting in Takayasu arteritis." 10/01/1993 - "Takayasu arteritis: initial and long-term follow-up in 16 patients after percutaneous transluminal angioplasty of the descending thoracic and abdominal aorta." 09/01/1993 - "Percutaneous transluminal angioplasty in patients with Takayasu arteritis: five-year experience." 10/01/1992 - "Balloon angioplasty of the aorta in Takayasu's arteritis: initial and long-term results." Order ALL the reference details at left...
3.	Aftercare (After-Treatment) 12/01/1994 - "Remission of nephrotic syndrome in a patient with renal amyloidosis associated with Takayasu's arteritis after treatment with dimethylsulphoxide." Order ALL the reference details at left...
4.	Transplants (Transplant) 02/01/2002 - "Composite graft replacement after aortic valvuloplasty in Takayasu arteritis." 09/01/2000 - "CONCLUSIONS: Carotid vein bypass for Takayasu arteritis, particularly, the pantaloon vein graft bypass is recommended for those of whom all aortic arch branches are occluded, resulting in severe brain ischaemia" 09/01/2000 - "BACKGROUND: We have adopted an all-autogenous-vein-graft policy in carotid reconstruction for Takayasu arteritis, namely an ascendo-right carotid and right subclavian (axillary) arteries bypass using a pantaloon vein graft for patients all of whose arch branches are occluded, and an extra-anatomical bypass from the right subclavian artery for patients whose brachiocephalic artery is the only arch branch that remains patent" 09/01/2000 - "Carotid artery reconstruction for Takayasu's arteritis the necessity of all-autogenous-vein graft policy and development of a new operation." 05/01/2000 - "When graft replacement of the ascending aorta and aortic arch and extra-anatomic bypass grafting were performed in a 72-year-old japanese woman with Takayasu's arteritis, which was complicated by aortic dissections localized in the ascending and abdominal aortae, the postoperative course of this patient was satisfactory" Order ALL the reference details at left...
5.	Angioplasty (Angioplasties) 06/01/2007 - "SUBJECT: Supraaortic angioplasty is often not feasible in patients with Takayasu's arteritis because of involvement of long segment of arteries" 03/01/2007 - "Feasibility of angioplasty and stenting for abdominal aortic lesions adjacent to previously stented visceral artery lesions in patients with Takayasu arteritis." 10/01/2004 - "Bilateral coronary ostial patch angioplasty with autologous pericardium in Takayasu arteritis: a case requiring replacement of the aortic valve and ascending aorta." 02/01/2002 - "We present about three observations of patients suffering from TAKAYASU's arteritis two of home have necessitated one carotidien's angioplasties" 05/01/1993 - "Multivessel angioplasty in Takayasu's arteritis." Order ALL the reference details at left...

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