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Tabes Dorsalis

Parenchymatous NEUROSYPHILIS marked by slowly progressive degeneration of the posterior columns, posterior roots, and ganglia of the spinal cord. The condition tends to present 15 to 20 years after the initial infection and is characterized by lightening-like pains in the lower extremities, URINARY INCONTINENCE; ATAXIA; severely impaired position and vibratory sense, abnormal gait (see GAIT DISORDERS, NEUROLOGIC), OPTIC ATROPHY; Argyll-Robertson pupils, hypotonia, hyperreflexia, and trophic joint degeneration (Charcot's Joint; see ARTHROPATHY, NEUROGENIC). (From Adams et al., Principles of Neurology, 6th ed, p726)
Also Known As:
Spinal Cord Syphilis; Spinal Meningovascular Syphilis; Syphilitic Meningomyelitis; Tabes Spinalis; Tabetic Neurosyphilis; Ataxia, Locomotor; Ataxias, Locomotor; Locomotor Ataxias; Meningomyelitides, Syphilitic; Meningomyelitis, Syphilitic; Meningovascular Syphilis, Spinal; Neurosyphilis, Tabetic; Spinalis, Tabes; Syphilis, Spinal Meningovascular; Syphilitic Meningomyelitides; Locomotor Ataxia; Myelosyphilis; Syphilis, Spinal Cord
Networked: 62 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Tonic Pupil
2. Neurosyphilis (General Paresis of the Insane)
3. Pain (Aches)
4. Syphilis
5. Sciatica (Sciatic Neuralgia)

Experts

1. Zheng, Wei-Hong: 2 articles (04/2013 - 01/2013)
2. Wu, Jing-Yi: 2 articles (04/2013 - 01/2013)
3. Liu, Gui-Li: 2 articles (04/2013 - 01/2013)
4. Dong, Jie: 2 articles (04/2013 - 01/2013)
5. Yang, Tian-Ci: 2 articles (04/2013 - 01/2013)
6. Su, Yuan-Hui: 2 articles (04/2013 - 01/2013)
7. Liu, Li-Li: 2 articles (04/2013 - 01/2013)
8. Zhang, Hui-Lin: 2 articles (04/2013 - 01/2013)
9. Lin, Li-Rong: 2 articles (04/2013 - 01/2013)
10. Tong, Man-Li: 2 articles (04/2013 - 01/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Tabes Dorsalis:
1. Valproic Acid (Valproate, Semisodium)FDA LinkGeneric
2. Dizocilpine Maleate (Dizocilpine)IBA
3. Penicillins (Penicillin)FDA Link
4. Syphilitic aseptic meningitisIBA
5. tertiary SyphilisIBA
6. Procaine (Novocaine)FDA LinkGeneric
7. CortisoneIBA
8. Plant Preparations (Preparation, Plant)IBA
9. Butyric Acid (Butanoic Acid)IBA
10. Interferon-alpha (Interferon Alfa)FDA Link

Therapies and Procedures

1. Arthroplasty
2. Spinal Anesthesia
3. Laminectomy
4. Analgesia
5. Rhizotomy