|2.||Congenital Abnormalities (Deformity)
|5.||Acrocephalosyndactylia (Apert Syndrome)
|1.||Mooney, Mark P: 22 articles (05/2015 - 03/2002)|
|2.||Siegel, Michael I: 17 articles (09/2012 - 03/2002)|
|3.||Cooper, Gregory M: 12 articles (01/2013 - 07/2004)|
|4.||Rogers, Gary F: 10 articles (09/2015 - 09/2002)|
|5.||Bartlett, Scott P: 9 articles (07/2015 - 06/2002)|
|6.||Mulliken, John B: 9 articles (03/2013 - 09/2002)|
|7.||Losee, Joseph E: 9 articles (09/2012 - 05/2005)|
|8.||Losken, H Wolfgang: 9 articles (04/2007 - 03/2002)|
|9.||Wall, Steven A: 7 articles (12/2015 - 08/2004)|
|10.||Wilkie, Andrew O M: 7 articles (03/2013 - 08/2004)|
03/01/2007 - "The purpose of this study was to test whether the severity of the cranial phenotype in Muenke syndrome infants with unicoronal synostosis is greater than in infants with nonsyndromic unicoronal synostosis. "
01/01/2011 - "Coronal synostosis syndrome (Muenke syndrome): the value of genetic testing versus clinical diagnosis."
11/01/2011 - "Muenke syndrome caused by the FGFR3(P250R) mutation is an autosomal dominant disorder mostly identified with coronal suture synostosis, but it also presents with other craniofacial phenotypes that include mild to moderate midface hypoplasia. "
09/01/2012 - "Muenke syndrome is characterized by coronal suture synostosis, midface hypoplasia, subtle limb anomalies, and hearing loss. "
04/01/2011 - "Two patients had bilateral coronal suture synostosis with Muenke syndrome and two patients had Apert syndrome. "
01/01/1995 - "Treatment was by excision of 1 cm of the shaft just below the synostosis and interposition of a radial head silicone implant. "
06/01/1978 - "Five years after an untreated ulnar fracture, a young man seen with no active or passive forearm rotation was found to have a radio-ulnar synostosis, which was surgically excised with interposition of a silicone membrane and soft tissue to decrease any tendency for new formation of the synostosis."
11/01/1997 - "Congenital metacarpal synostosis treated by longitudinal osteotomy and placement of a silicone wedge."
01/01/1995 - "Proximal radio-ulnar synostosis treated by interpositional silicone arthroplasty. "
07/01/2001 - "This study reports on the incidence of a synostosis between the ring-small metacarpal bases in patients with Apert syndrome and describes a technique to resect the synostosis and insert silicone sheets to improve hand function. "
|3.||salicylhydroxamic acid (SHAM)IBA
03/01/1993 - "The study sample consisted of 10 sham controls, 14 experimental animals with bilateral CS immobilization, and one animal with congenital, bilateral CS synostosis. "
08/01/2009 - "RESULTS - Animals that received control osteoblasts, sham surgery, or no surgery demonstrated normal skull growth and coronal suture histology, whereas animals transplanted only with FGFR2 mutant osteoblasts showed evidence of bridging synostosis on the calvarial dural surface. "
03/01/2011 - "Twenty-six, 10-day old rabbits with familial, delayed-onset, coronal suture synostosis were randomly divided into three groups: (1) the sham surgical control group, (2) the bovine serum albumin-treated group [10 μg/suture (protein/vehicle controls)], and (3) the noggin therapy group (10 μg/suture; experimental group). "
|4.||Kantaputra Gorlin syndromeIBA
09/01/2008 - "This study reports a male patient with an early diagnosed mesomelic dysplasia Kantaputra type (MIM*156232), characterized by symmetric, bilateral forearm and lower leg shortening with feet malformations and ankle-tarsal synostoses. "
01/01/1998 - "Mesomelic dysplasia Kantaputra type (MDK) (MIM *156232) is a new autosomal dominant skeletal dysplasia characterized by dwarfism, shortening of the forearms/lower-legs, carpal/tarsal synostosis, and dorsolateral foot deviation. "
|5.||Transcription Factor AP-2IBA
07/01/2007 - "Antley-Bixler syndrome (ABS) is characterized by craniofacial dysmorphism and radiohumeral synostosis with other associated anomalies. "
02/01/2004 - "Antley-Bixler syndrome with radioulnar synostosis."
05/18/1998 - "The Antley-Bixler syndrome (ABS) is a rare syndrome with synostosis of cranial sutures and elbow joints as minimal diagnostic criteria. "
03/01/1996 - "It is reasonable to propose that characteristic craniofacial appearance associated with the synostosis of the elbow joints of various forms should be considered minimal diagnostic criteria of the Antley-Bixler syndrome."
03/01/1996 - "Antley-Bixler syndrome: a disorder characterized by congenital synostosis of the elbow joint and the cranial suture."
01/01/2014 - "Surgical induction of metacarpal synostosis for treatment of ectrodactyly in a dog."
11/01/2005 - "Patients with isolated ulnar-sided hand deficiency such as ectrodactyly of the ring and/or small fingers or synostosis of the small metacarpal of the ring finger in the presence of a normal forearm may be diagnosed as having type 0 ULD. "
01/01/1991 - "Unilateral ectrodactyly, metatarsal synostosis, and hypoplasia in an Eskimo."
09/01/2008 - "The pattern of limb anomalies in these patients, which range from ectrodactyly to limb synostosis, is very uncommon in 22q11 deletion syndrome. "
02/01/2004 - "Bilateral complete radioulnar synostosis associated with ectrodactyly and sensorineural hearing loss: a variant of SHFM1."
|8.||Type 3 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 3)IBA
12/01/2001 - "Clinical characteristics of patients with unicoronal synostosis and mutations of fibroblast growth factor receptor 3: a preliminary report."
04/01/2000 - "Fibroblast growth factor receptor 3 mutation in nonsyndromic coronal synostosis: clinical spectrum, prevalence, and surgical outcome."
03/01/1997 - "Here we present 61 individuals from 20 unrelated families where coronal synostosis is due to an amino acid substitution (Pro250Arg) that results from a single point mutation in the fibroblast growth factor receptor 3 gene on chromosome 4p. "
07/01/2001 - "Premature calvarial synostosis and epidermal hyperplasia (Beare-Stevenson syndrome-like anomalies) resulting from a P250R missense mutation in the gene encoding fibroblast growth factor receptor 3."
04/01/1998 - "To determine whether the autosomal dominant fibroblast growth factor receptor 3 (FGFR3) Pro250Arg mutation causes anterior plagiocephaly, patients with either apparently sporadic unicoronal synostosis (N = 37) or other forms of anterior plagiocephaly (N = 10) were studied for this mutation. "
|9.||Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
05/01/2007 - "Syndromic synostosis has been found to be associated with mutations of the fibroblast growth factor receptor family (FGFR1, -R2, -R3), TWIST1, MSX2, and EFNB1. "
12/01/2004 - "The most common syndromic synostoses reflect changes in fibroblast growth factor receptor (FGFR) activity related to mutations in the genes coding for these receptors. "
05/01/2015 - "The FM shape and area is significantly altered in fibroblast growth factor receptor (FGFR)-related brachycephaly syndromes (Crouzon, Pfeiffer, and Apert), whereas in patients with Saethre-Chotzen syndrome (TWIST-1 mutation) and isolated non-syndromic bicoronal synostosis, the shape and mean FM area was not statistically different from that of normals. "
08/01/2004 - "Muenke syndrome, also known as FGFR3-associated coronal synostosis, is defined molecularly by the presence of a heterozygous nucleotide transversion, c.749C>G, encoding the amino acid substitution Pro250Arg, in the fibroblast growth factor receptor type 3 gene (FGFR3). "
|10.||Dihydrotachysterol (AT 10)IBA
09/01/2006 - "Serial magnetic resonance imaging scans and intracranial pressure measurements were obtained at 10, 25, and 42 days of age from 18 rabbits: six controls, six with delayed-onset synostosis, and six with early-onset synostosis. "
05/01/2005 - "The results demonstrate that rabbits with early-onset synostosis had significantly (p<0.001) dilated and larger lateral ventricles (by 77% at 10 days of age) than wild-type and delayed-onset synostosis rabbits, which progressively worsened by day 42. "
06/01/1979 - "The synchondroses of the vertebrae transplanted at 10 days did not differ very much from those of the host 5, 10 or 15 days after the operation, whereas in the vertebrae transplanted at 25 days the synchondroses underwent synostosis earlier than in situ. "
05/01/2005 - "Eighteen rabbits (6 wild-type controls, 6 with early-onset [ approximately 21 days gestation], and 6 with delayed-onset [approximately 25 days post-gestation] coronal suture synostosis) had magnetic resonance imaging (MRI) at 10, 25, and 42 days of age. "
03/01/2013 - "The patient was diagnosed with right coronal synostosis at age 10 weeks requiring surgery, and bilateral ectopia lentis with high myopia at 10 months. "
01/01/2015 - "A child with isolated single suture synostosis and any comorbidity had a significantly greater risk of any complication (P < 0.001; odds ratio, 3.8) and specifically an increased risk of major complication (P = 0.031; odds ratio, 6.0). "
03/01/2010 - "The results indicate that nonsyndromic multiple-suture synostosis can be safely and effectively treated using endoscopic techniques. "
07/01/2007 - "Fronota-facial advancement cured the brachycephalic complicating with Apert or Crouzon which caused by coronal synostosis and cranial basal suture synostosis. "
05/01/1991 - "Midline craniectomy for sagittal suture synostosis: comparative efficacy of two barriers to calvarial reclosure."
09/01/2015 - "The aim of the this study was to describe changes in head circumference (HC) and cephalic index (CI) in children with sagittal suture synostosis before surgery, by putting the child to bed in supine position lying on the back of the head. "
10/01/2015 - "One-stage rotational osteotomy of the proximal third of the ulna and distal third of the radius with segmental bone resection is a simple and safe treatment for patients with congenital radioulnar synostosis. "
12/01/2015 - "Safety and Efficacy of Derotational Osteotomy for Congenital Radioulnar Synostosis."
06/01/1986 - "Fibular osteotomy and complications from tibiofibular synostosis are eliminated. "
12/01/2007 - "The present study evaluates the result of two-stage double-level rotational osteotomy of both the radius and ulna in the treatment of severe congenital radioulnar synostosis. "
01/01/2003 - "The purpose of this study was to describe the results of a newly developed method of correction osteotomy for congenital radioulnar synostosis. "
05/01/2006 - "The purpose of this study is to report our experience with synostosis resection and interposition of tensor fascia lata grafts. "
04/01/2014 - "Reconstruction may require bone grafts, tibiofibular synostosis, free microvascular soft tissue or bone transplants. "
02/01/2014 - "It is concluded that forehead remodelling with a calvarial bone graft creates a more symmetrical forehead than FOA and may, therefore, be a better alternative for treatment of unicoronal synostosis."
01/01/2014 - "The synostosis was treated by resection and fascia lata interposition graft. "
08/01/2012 - "Bone graft was also used to the distal tibiofibular space to achieve distal tibiofibular synostosis. "
06/01/2011 - "Reoperations were needed at a significantly greater rate overall and for noninfectious complications following bone-bridge synostosis compared with modified Burgess transtibial amputations. "
10/01/2013 - "Recent studies, however, have suggested an increase in complication and reoperation rates in transtibial amputations that received a bridge synostosis compared with standard transtibial amputations. "
06/01/2011 - "The purpose of this study was to compare the early and intermediate-term complications leading to reoperation between the modified Burgess and modified Ertl tibiofibular synostosis in combat-related transtibial amputations. "
05/15/2013 - "We compared self-reported functional outcomes associated with two surgical techniques for transtibial amputation: bridge synostosis (modified Ertl) and non-bone-bridging (modified Burgess). "
05/15/2013 - "Comparison of functional outcomes following bridge synostosis with non-bone-bridging transtibial combat-related amputations."
01/01/2004 - "Patients with large tibial defects obtained good results with both tibiofibular synostosis and Ilizarov distraction osteogenesis. "
04/01/2012 - "Midface distraction osteogenesis (DO) in craniofacial synostosis (CFS) patients has been described by several authors. "
12/01/2006 - "Distraction osteogenesis to improve limb function in congenital bilateral humeroradioulnar synostosis."
01/01/2004 - "Distraction osteogenesis of the cranial vault for the treatment of craniofacial synostosis."
07/01/2003 - "Complications associated with gradual cranial vault distraction osteogenesis for the treatment of craniofacial synostosis."