Syndrome

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83760 relevant articles (3264 outcomes, 6709 trials/studies) found for this Disease

Description: A symptom complex of unknown etiology, that is characteristic of a particular abnormality.

Also Known As:

Syndromes

Relationship Network

Disease Context: Research Results

Signs and Symptoms Pathological Conditions

Pathologic Processes: 2442

Disease

Syndrome: 83760

Related Diseases

1.	Pain (Aches)
2.	Neoplasms (Cancer)
3.	Seizures (Seizure)
4.	Insulin Resistance
5.	Hypertension (High Blood Pressure)

Experts

1.	Yuki, N: 17 articles (01/2005 - 02/2000)
2.	Barrett, P Hugh R: 16 articles (10/2008 - 02/2003)
3.	Watts, Gerald F: 16 articles (10/2008 - 02/2003)
4.	Eggermann, T: 16 articles (01/2008 - 07/2000)
5.	Eggermann, Thomas: 15 articles (04/2008 - 09/2002)
6.	Chan, Dick C: 14 articles (10/2008 - 03/2003)
7.	Yuki, Nobuhiro: 13 articles (02/2008 - 01/2002)
8.	Wollmann, H A: 13 articles (01/2008 - 07/2000)
9.	van Doorn, P A: 12 articles (09/2007 - 03/2000)
10.	Matsuzawa, Yuji: 12 articles (04/2007 - 07/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Syndrome:

1.	Insulin (Novolin)FDA Link 02/15/2004 - "The basal hepatic insulin production mediated by hydrodynamics-based administration improved the glycemic control in type 1 diabetes dramatically and ameliorated diabetic syndromes. " 03/01/1992 - "Therefore attention is focused on the period of clinical manifestation of the diabetic syndrome and its early stages when by early diagnosis and intensive insulin or immunosuppressive treatment it is still possible to preserve a substantial proportion of functional B-cells and influence in an effective manner the onset and duration of remission. " 01/01/2005 - "CB1 blockade helps regulate food intake and adipose tissue metabolism, contributing to improved insulin sensitivity and other features of the metabolic syndrome. " 10/01/2009 - "Recent studies have shown that they influence insulin sensitivity and incidence of the metabolic syndrome. " 10/01/2009 - "Taken together, these observations may inform the future clinical nutrigenomics study designs and indicate that a single dose of VOO can elicit quantifiable and rapid changes in gene expression in targets that are mechanistically relevant for insulin sensitivity and the metabolic syndrome." Order ALL the reference details at left...
2.	Adrenal Cortex Hormones (Corticosteroids)IBA 01/01/1995 - "The authors report the case of a 65-year-old man who had an evolving case of Schnitzler's syndrome with lytic bone lesions which was unresponsive to several drugs, and which dramatically improved with small quantities of corticosteroids. " 04/01/1980 - "A case of acute inflammatory polyradioculoneuropathy (IPN, Guillain-Barré syndrome) not responding to oral corticosteroids but showing marked improvement on parenteral corticosteroids is reported. " 04/01/2009 - "In 1972, Drs Liggins and Howie published a landmark article demonstrating that antenatal corticosteroids significantly reduced the frequency of respiratory distress syndrome and neonatal mortality. " 07/01/2006 - "Is the long-term use of systemic corticosteroids beneficial in the management of Behçet's syndrome?" 08/01/2002 - "RESULTS: Prophylactic corticosteroids were not associated with a significant reduction in respiratory distress syndrome (adjusted odds ratio, 0.7; 95% CI, 0.2-2.0). " Order ALL the reference details at left...
3.	Intravenous Immunoglobulins (IVIG)FDA Link 08/15/2007 - "Similarly, trials failed to establish a role for IVIG in the treatment of secondary or primary progressive MS. Most consistent beneficial results with a reduction of relapse rates and a slowing of disability have been obtained in relapsing-remitting MS including clinically isolated syndromes although a most recent study did not confirm a reduction of disease activity based on clinical and MRI findings. " 05/01/1988 - "In other areas, such as in Kawasaki's syndrome, IVIG therapy have been shown to be highly beneficial in preventing long term disease sequelae by some investigators, but the field remains controversial. " 11/01/1995 - "For Guillain-Barré syndrome the efficacy of intravenous immune globulin has been proven in a randomized clinical trial. " 04/01/2005 - "In Guillain-Barré syndrome (GBS),IVIg and PE are similarly effective in accelerating the recovery but there is still little evidence that they can reduce mortality or long-term disability. " 10/01/2006 - "Despite normal distal conduction studies, a clinical diagnosis of Lewis-Sumner syndrome was made and the patient responded well to intravenous immunoglobulins. " Order ALL the reference details at left...
4.	HormonesIBA 01/01/1980 - "A high therapeutic efficacy of the hormones in the treatment of amnestic syndromes is demonstrated." 01/01/1990 - "Löfgren's syndrome was effectively treated with steroid hormones." 01/01/2003 - "Future research should disclose why the deprivation of ovarian hormones has a variable impact on women's functioning, and further trials ought to reveal effective and safe treatments for women suffering from this syndrome." 08/01/2005 - "This makes it useful in the treatment of the syndrome of resistance to thyroid hormone action, where the typical mutation affects only the beta receptor. " 01/01/2007 - "AUTHORS' CONCLUSIONS: There is no evidence from controlled clinical trials that postnatal thyroid hormone treatment reduces the severity of respiratory distress syndrome, neonatal morbidity or mortality in preterm infants with respiratory distress syndrome." Order ALL the reference details at left...
5.	Glucose (Dextrose)FDA LinkGeneric 11/01/2002 - "Although interventions targeting elements of this syndrome have dramatically reduced cardiovascular risk, the impact of glucose-lowering has been more disappointing. " 01/01/2006 - "These results suggest that the rare allele of the MTP I128T polymorphism may be protective against impaired glucose tolerance, type 2 diabetes and other parameters of the metabolic syndrome." 08/01/2008 - "OBJECTIVE: To assess the efficacy of 1-h plasma glucose concentration and the metabolic syndrome in predicting future risk of type 2 diabetes. " 04/01/1986 - "Medical benefits (such as improved glucose tolerance, lowered blood pressure, healed Pickwick syndrome, etc.) were maintained during the follow-up (average five years). " 10/01/2009 - "The aim of the study is to determine the effects of short-term high-intensity exercise on arterial function and glucose tolerance in obese individuals with and without the metabolic syndrome (MetSyn). " Order ALL the reference details at left...
6.	Immunoglobulins (Immunoglobulin)IBA 01/01/2001 - "OBJECTIVES: To determine the efficacy of intravenous immunoglobulin in comparison with no treatment or other treatments for treating Guillain-Barré syndrome and to determine the most efficacious dose. " 09/01/1997 - "Human immunoglobulin is an effective treatment for Guillain-Barré syndrome, although the mechanism of action is not understood. " 01/01/1997 - "Immune globulins are effective in severe pediatric Guillain-Barré syndrome." 04/25/1992 - "[Therapeutic efficacy of polyvalent immunoglobulins in autoimmune Lambert-Eaton's syndrome]" 01/01/1997 - "We conclude that immune globulins are effective and safe in severe childhood-onset Guillain-Barré syndrome and therefore may serve as the initial treatment of choice." Order ALL the reference details at left...
7.	lamotrigine (Lamictal)FDA LinkGeneric 06/01/1999 - " (4) In patients with the Lennox-Gastaut syndrome, the addiction of lamotrigine to an ongoing inadequately effective treatment proved more effective than a placebo in two methodologically sound trials. " 12/18/1997 - "METHODS: We conducted a double-blind, placebo-controlled trial of the antiepileptic drug lamotrigine in patients with the Lennox-Gastaut syndrome. " 08/31/2009 - "Sjögren's syndrome precipitated by lamotrigine treatment." 11/01/2006 - "Lamotrigine is well-tolerated and secondary aggravation of epileptic syndromes has rarely been reported. " 09/01/2005 - "For women who are pregnant or trying to conceive, lamotrigine was treatment of choice for both syndrome types. " Order ALL the reference details at left...
8.	Valproic Acid (Valproate, Semisodium)FDA LinkGeneric 08/01/1996 - "Valproic acid is known to be most effective in the basic crises of these two syndromes, namely the typical absence attacks. " 06/01/1996 - "RESULTS: At day 5, patients with serum valproate levels > or = 45 micrograms/ml were two to seven times as likely as patients with levels < 45 micrograms/ml to show 20% or greater improvement in scores on the manic syndrome subscale, the behavior and ideation subscale, elevated mood, increased activity, motor hyperactivity, and psychosis. " 01/01/1994 - "Thus, valproic acid may be an effective treatment for Isaac's syndrome where these other drugs have failed." 05/01/1983 - "The results show that sodium valproate is effective in some cases of Nelson's syndrome. " 06/01/2006 - "AIMS: This study was conducted to compare the efficacy of valproic acid in familial versus sporadic cases of this syndrome. " Order ALL the reference details at left...
9.	Carbamazepine (Tegretol)FDA LinkGeneric 01/01/2002 - "Efficacy of early immunosuppressive therapy in a child with carbamazepine-associated vanishing bile duct and Stevens-Johnson syndromes." 04/01/1988 - "They tolerated the medication well and their behavior improved, consistent with carbamazepine's efficacy for agitation in other syndromes. " 04/01/1988 - "These time course variations may indicate that different mechanisms underlie the efficacy of carbamazepine in the differential neuropsychiatric syndromes. " 02/01/2008 - "Treatment with carbamazepine at study entry was associated with a lower prevalence rate of metabolic syndrome. " 07/01/2006 - "The clinical suspicion of a paroxysmal syndrome prompted a trial of carbamazepine, which resulted in complete cessation of the symptoms. " Order ALL the reference details at left...
10.	Risperidone (Risperdal Consta)FDA LinkGeneric 12/01/2006 - "Pisa syndrome-like peculiar posture occurred while running was successfully improved with risperidone." 09/01/2006 - "A significantly greater proportion of patients treated with risperidone achieved > or =20% reduction from baseline Positive and Negative Syndrome Scale total score at weeks 1, 2, 6, and at end point (last observation carried forward: P< or =0.04). " 01/01/2005 - "Long-acting risperidone was associated with a significant reduction in total Positive and Negative Syndrome Scale (PANSS) score (mean change +/- standard error [S.E.] at endpoint: long-acting risperidone, -9.27 +/- 1.44, n = 133; placebo, 0.72 +/- 2.59, n = 41; P < 0.001), and a significantly higher rate of treatment response, defined as > or = 20% reduction in total PANSS score (50% vs. 27%, P < 0.05). " 06/01/2004 - "RESULTS: In the 188 (25.9%) patients receiving conventional depot antipsychotic monotherapy at entry, mild-to-moderate mean (+/-S.D.) Positive and Negative Syndrome Scale (PANSS)-total scores improved significantly after receiving long-acting risperidone (64.2 +/- 18.9 to 58.2 +/- 20.3; P < 0.001). " 06/01/2004 - "Improvements in CGI severity ratings and scores on the Montgomery-Asberg Depression Rating Scale, Positive and Negative Syndrome Scale, and GAS were also significantly greater among patients receiving risperidone than those given placebo. " Order ALL the reference details at left...

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 05/01/1999 - "Wallstent placement could be an extremely useful treatment for SVC syndrome and should be the treatment of choice in all cases where SVC obstruction occurs or recurs, following chemotherapy or radiotherapy." 10/01/1986 - "Most patients (75%) developed the syndrome 6 to 12 months after starting chemotherapy, and 60% were in remission. " 01/01/1994 - "Initial results of ATRA in newly diagnosed APL showed that this drug was associated with a high complete remission (CR) rate but also (i) to a risk of hyperleukocytosis and of ATRA syndrome, (ii) to rapid relapse unless ATRA was followed by intensive chemotherapy. " 05/01/1993 - "We can conclude that the incidence of this pathology is high and has a tendency to increase; the approach in primary care needs to be improved; little importance is given to rectal examination and drug therapy affords excellent control of the syndrome." 11/01/2005 - "We review the safety and efficacy of dietary and drug therapy, and propose an updated diagnostic and therapeutic algorithm that includes the metabolic syndrome. " Order ALL the reference details at left...
2.	Continuous Positive Airway Pressure 11/01/2002 - "The health status impairment in sleep apnoea/hypopnoea syndrome patients is markedly improved by continuous positive airway pressure compared to a modest improvement with conservative lifestyle strategies using the standard gamble utility, which may be incorporated in effectiveness and economic analyses. " 09/01/1997 - "A surgical cure for adult obstructive sleep apnoea syndrome (OSAS) is an attractive alternative to nasal continuous positive airway pressure, but current research suggests that uvulopalatopharyngoplasty is not effective in all patients. " 05/01/2006 - "Meta-analyses of randomised controlled trials have shown that the severe presentation of the syndrome (apnoea hypopnoea index (AHI) >30/hour) is effectively treated with continuous positive airway pressure (CPAP). " 04/01/2009 - "In moderate-to-severe obstructive sleep apnoea/hypopnoea syndrome, treatment with continuous positive airway pressure has been shown to be effective. " 04/01/2009 - "Continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnoea syndrome (OSAS) but therapy adherence is often low. " Order ALL the reference details at left...
3.	Plasma Exchange 09/01/2008 - "Whilst randomised control trials are undoubtedly the best way to demonstrate whether plasma exchange or infusion alone is the best first-line treatment for patients with atypical haemolytic uremic syndrome (aHUS), individual case reports can provide valuable information. " 12/01/1999 - "The most recent approach is aggressive plasma exchange (PE) employing cryopoor plasma for replacement, based on the pathogenetic relevance given to exceedingly large Von Willebrand (VWF) multimers in the determination of the syndrome with normalization during remission. " 10/01/1992 - "A 19-year-old man with Guillain-Barré syndrome (GBS), who had been bedridden, dramatically improved after plasma exchange despite electrophysiological evidence of severe axonal damage. " 12/04/1990 - "Plasma exchange has proven to be effective in diseases of established or presumed autoimmune etiology as well as in hyperviscosity syndromes and some rare metabolic disorders. " 07/01/1990 - "Emergency plasma exchange produced marked improvement in the clinical manifestations of hyperviscosity syndrome. " Order ALL the reference details at left...
4.	Aftercare (After-Treatment) 09/01/2008 - "RESULTS: The clinical therapeutic effect and the total effective rate for TCM syndromes were 92.0% and 94.0% in the regulating kidney and smoothing liver needling group, 86.0% and 88.0% in the routine acupuncture group and 78.0% and 84.0% in the Chinese medicine group, with a significant difference among the 3 groups, the former being better than the other two groups; after treatment, serum PRL, P, P/E2 significantly improved in all the 3 groups (P < 0.05) and the regulating kidney and smoothing liver needling group was better than other two groups in decreasing PRL and increasing P, P/E2 (P < 0.05); and E2, CD8+, CD4+/CD8+ significantly improved in the regulating kidney and smoothing liver needling group and the routine acupuncture group, the former being better than the later in decreasing E2 (P < 0.05). " 07/01/2008 - "RESULTS: In the treated group after treatment, the efficacy for improving TCM syndrome reached 73.33% (44/60 cases), their half-year survival rate being 83.33% (50/60 cases); while those in the control group were 52.63% (30/57 cases) and 70.18% (40/57 cases) respectively, significant difference was shown between the two groups (P <0.05). " 08/01/2004 - "In the treated group after treatment, the integrals of CCSE, FAQ and MMSE significantly increased (P < 0.05 or P < 0.01), the TCM Syndrome scoring decreased (P < 0.01), the scoring of QOL significantly improved, the mean BBF increased (P < 0.05 or P < 0.01), and the cerebral arterial resistance index improved significantly. " 12/01/1991 - "There was significant difference in both the two indexes between the two groups, 2. After treatment, the syndromes of the patients were obviously relieved. " 11/01/2007 - "RESULTS: In the treated group after treatment, the syndrome of Shen-deficiency and the above-mentioned indexes tested were improved better than those in the control group, respectively. " Order ALL the reference details at left...
5.	Transplants (Transplant) 01/01/1991 - "This syndrome occurred in 9 patients (29%) and was attributed to primary graft failure in 2, increased pulmonary vascular resistances in 6 and multiple factors in 1. Although not significant, two factors may increase early survival: young age (less than or equal to 1 year) at operation and improved technique of graft preservation." 03/01/1982 - "Spiral vein bypass graft provides effective treatment for SVC obstruction with immediate and long-term relief of SVC syndrome." 07/01/2006 - "OBJECTIVE: Internal thoracic artery (ITA) grafting to the left anterior descending artery (LAD) may have catastrophic consequences and can be fatal due to "ITA malperfusion syndrome." We have investigated the efficacy of a second graft in this syndrome. " 07/01/2006 - "Improved graft function in liver-transplanted patients after partial splenic embolization: reversal of splenic artery steal syndrome?" 07/01/2005 - "In our experience, LDLTx of a left liver graft has an increased risk of "small for size syndrome," but patients, both donors and recipients, report improved outcomes." Order ALL the reference details at left...

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