|1.||Gustatory Sweating (Frey's Syndrome)
|3.||Congenital Abnormalities (Deformity)
|1.||de Bree, Remco: 3 articles (04/2012 - 08/2007)|
|2.||Shi, Zongdao: 2 articles (01/2015 - 02/2013)|
|3.||Li, Chunjie: 2 articles (01/2015 - 02/2013)|
|4.||Li, Longjiang: 2 articles (01/2015 - 02/2013)|
|5.||Li, Chao: 2 articles (09/2013 - 07/2011)|
|6.||Zhao, Hong-wei: 2 articles (09/2013 - 02/2005)|
|7.||Fan, Jin-chuan: 2 articles (09/2013 - 07/2011)|
|8.||Pan, Jian: 2 articles (02/2013 - 02/2005)|
|9.||Steffen, A: 2 articles (06/2012 - 02/2012)|
|10.||Heffelfinger, Ryan N: 2 articles (09/2009 - 02/2008)|
|1.||Botulinum Toxins (Botulinum Toxin)IBA
10/15/2000 - "In the current study, seven patients with severe, symptomatic Frey syndrome after parotidectomy were treated successfully with type A botulinum toxin. "
01/01/2002 - "Botulinum toxin A produces good results in the treatment of Frey syndrome. "
02/01/2012 - "Botulinum toxin is a widely accepted, effective treatment for Frey's syndrome. "
08/01/2007 - "Intracutaneous injection of botulinum toxin A is an effective, long-lasting, and well-tolerated treatment of Frey syndrome. "
10/06/2005 - "Botulinum toxin injected intracutaneously is a safe and effective method for the treatment of Frey's syndrome. "
|2.||Glycopyrrolate (Glycopyrronium Bromide)FDA LinkGeneric
09/05/2011 - "In this case a patient with diabetes suffering from gustatory hyperhidrosis was treated successfully with topical glycopyrrolate, an anticholinergic agent applied directly on the affected area."
04/26/1999 - "Gustatory sweating was relieved by application of glycopyrrolate and reappeared when the glycopyrrolate was briefly withdrawn to confirm its therapeutic effect. "
05/01/1996 - "Topical glycopyrrolate cream is an effective treatment of diabetic gustatory sweating without the adverse effects commonly found with oral anti-muscarinic medication."
01/01/1989 - "We therefore believe that the topical application of a 2% glycopyrrolate preparation is a safe and effective treatment for severe gustatory sweating following parotidectomy."
03/01/1997 - "A randomised controlled trial of topical glycopyrrolate, the first specific treatment for diabetic gustatory sweating."
|3.||Type A Botulinum Toxins (Botulinum A Toxin)FDA Link
04/01/2002 - "Increased botulinum toxin type A dosage is more effective in patients with Frey's syndrome."
06/01/1999 - "Such preliminary data, together with the review of the literature suggests, that the intracutaneous injection of botulinum toxin type A should now be the first line treatment option in patients with severe Frey syndrome."
03/01/1999 - "However, because the severity of recurrent gustatory sweating is reduced when compared with the severity of the initial gustatory sweating and because recurrent gustatory sweating remains amenable to reinjection of botulinum toxin type A, we believe that the intracutaneous injection of botulinum toxin type A should become the first-line treatment option in patients with gustatory sweating."
07/01/2004 - "Our study supports the widely accepted aspect that botulinum toxin type A could be the treatment of choice for gustatory sweating syndrome. "
11/01/2015 - "Efficacy and safety of botulinum toxin type A for treatment of Frey's syndrome: evidence from 22 published articles."
01/01/2000 - "However, analysis of the current results in patients with SMAS dissection revealed an incidence of Frey's syndrome of only 20%, the results of starch minor tests being positive in 76% with a statistically highly significant (p = 0.006) decrease in extent and intensity. "
01/01/2000 - "In a previous publication we found a 43% incidence of Frey's syndrome after parotid surgery without SMAS dissection and starch minor tests were positive in all 23 patients. "
09/01/1997 - "Minor's starch test showed total disappearance of gustatory sweating in 12 of the 15 treated patients. "
07/01/1976 - "Because the starch test reveals only the distribution of the gustatory sweating, a useful adjunct is described for investigating Frey's syndrome. "
03/01/1997 - "In four patients who had undergone unilateral parotidectomy, gustatory sweating and facial flushing were present after gustatory stimulation, and the presence of Frey's syndrome was confirmed with Minor's starch test in all patients. "
10/01/1993 - "Only one patient developed symptomatic Frey's syndrome, and one other patient had positive results on starch iodine testing. "
01/01/2015 - "We included randomised or quasi-randomised controlled trials (RCTs) in participants diagnosed with Frey's syndrome using a clinical standard such as Minor's starch-iodine test. "
10/01/2015 - "The Minor starch iodine test was positive in 3 patients (27%), although only 1 (9%) subjectively complained of gustatory sweating. "
12/01/2013 - "A subjective clinical questionnaire and an objective Minor's starch iodine test were performed to evaluate the incidence of Frey's syndrome. "
12/01/2013 - "To correlate Frey's syndrome with subjective symptoms, Minor's starch iodine test results, and infrared thermography measurements, and to discuss the utility of thermography as a quantitative diagnostic method. "
09/01/2013 - "The major advantages of this procedure include a reduction in complications such as facial nerve impairments and Frey's syndrome, and an improved cosmetic outcome."
02/01/2015 - "The use of a SCM flap seemed to prevent Frey's syndrome (Fischer test P=0.00001) and improved cosmetic results (Fisher test P<0.00001). "
09/01/2013 - "Parameters evaluated included facial nerve weakness, the occurrence of Frey's syndrome, cosmetic outcome, and recurrence. "
04/01/2012 - "The outcome measures of particular interest were the incidence of Frey's syndrome and cosmetic impairment. "
08/01/2008 - "SMAS fold flap and ADM repair of the parotid bed following removal of parotid haemangiomas via pre- and retroauricular incisions to improve cosmetic outcome and prevent Frey's syndrome."
|7.||onabotulinumtoxinA (Botox)FDA Link
08/01/2003 - "Botox A injection is a safe and effective treatment with long-lasting effects for patients with extensive gustatory sweating."
05/01/2006 - "The anticholinergic effects of Botox make it particularly suitable for the treatment of Frey's Syndrome. "
03/01/1998 - "Findings show that intracutaneous injection of BOTOX is a highly effective, safe, and minimally invasive treatment of Frey's syndrome with long-lasting therapeutic effect."
03/01/1998 - "Nineteen patients with severe gustatory sweating have been treated with BOTOX by intracutaneous injections into the affected skin areas. "
03/01/1998 - "Based on our experiences using this technique since December 1993, the purpose of this clinical investigation was to make an up-to-date report and demonstrate the duration of effect of BOTOX injections in patients with severe gustatory sweating. "
07/01/2009 - "Permacol produced good results in both postoperative facial contouring and prevention of Frey's syndrome."
07/01/2009 - "Our aim was to present the results of the use of porcine dermal collagen graft (Permacol) in the prevention of Frey's syndrome and face-contouring aesthetic deformities after operations on the parotid. "
02/01/2012 - "On the basis of our experience minimally invasive fat injections can be considered in the case of post-parotidectomy Frey syndrome, but patients should be informed that subsequent procedures may be needed to achieve a definitive result."
02/01/2012 - "We describe the use of fat injections into the parotid gland of four patients with post-parotidectomy Frey syndrome. "
02/01/2012 - "Fat injections may be useful in preventing the abnormal nerve neo-anastomoses sprouting to the sweat glands that are responsible for gustatory sweating, but have never been used before. "
02/01/2012 - "Fat injections for the management of post-parotidectomy Frey syndrome: a technical note."
06/01/2006 - "The effect of BTX injections for gustatory sweating obtained in this case was comparable to results reported using higher doses. "
02/01/2013 - "The present clinical evidence suggests that grafts are effective in preventing Frey syndrome after parotidectomy. "
07/01/2013 - " aim of this study is evaluate the outcomes of facial symmetry and symptomatic Frey syndrome in patients having dermofat graft during superficial parotidectomy.The"
02/01/2013 - "The relevant journals and reference lists of the included studies were manually searched for randomized controlled trials studying the effect and safety of different types of grafts for preventing Frey syndrome after parotidectomy. "
02/01/2013 - "Graft for prevention of Frey syndrome after parotidectomy: a systematic review and meta-analysis of randomized controlled trials."
02/01/2013 - "The muscle flaps can reduce by 81% the risk of Frey syndrome compared with the no-graft group (RR 0.19, 95% CI 0.13 to 0.27; P < .00001; GRADE quality of evidence: high). "
03/01/2006 - "Although there is no pathophysiologic explanation of gustatory sweating, these findings should be considered before planning thoracoscopic sympathectomy and patients should be thoroughly informed."
03/01/2006 - "Gustatory sweating is a frequent side effect after thoracoscopic sympathectomy. "
03/01/2006 - "Overall, gustatory sweating occurred in 32% of patients, and the incidence was significantly associated with extent of sympathectomy (p = 0.04). "
05/01/2003 - "Additional data regarding sensory findings, surgical details of the sympathectomy, sweat patterns, and incidence of abnormal body sweating and pathologic gustatory sweating were extracted from the patients' charts or obtained in follow-up appointments. "
10/01/1977 - "In a series of 100 bilateral upper dorsal sympathectomies performed for palmar hyperhidrosis, gustatory sweating and other gustatory phenomena were reported by 68 of 93 patients (73%), followed up for an average of 1 1/2 years. "
11/01/2003 - "Currently, the intradermal injection of BTX is the standard treatment of Frey's syndrome. "
11/01/2007 - "Intradermal injection of botulinum toxin type A for patients with Frey's syndrome is not only effective with no side effect but also minimally invasive. "
10/01/2008 - "A questionnaire concerning functional, social and emotional aspects of Frey's syndrome (14 questions, with responses on a zero to three point scale) was administered to 17 patients (13 women and four men) before and one month after intradermal injection of botulinum toxin A. "
11/01/2007 - "The present report supports that intradermal injection of botulinum toxin type A should be the treatment of choice for Frey's syndrome."
01/01/2005 - "Botulinum toxin: 28 patients affected by Frey's syndrome treated with intradermal injections."