Surface-Active Agents (Surfactants)

Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics.
Also Known As:
Surfactants; Amphiphilic Agents; Surface Active Agents; Tensides; Active Agents, Surface; Agents, Amphiphilic; Agents, Surface Active; Agents, Surface-Active
Networked: 431 relevant articles (24 outcomes, 45 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Eckmann, David M: 5 articles (09/2013 - 01/2004)
2. Notter, Robert H: 5 articles (05/2008 - 12/2004)
3. Wang, Zhengdong: 5 articles (05/2008 - 12/2004)
4. Inami, Yoshihiro: 4 articles (11/2014 - 01/2012)
5. Armstead, Stephen C: 4 articles (09/2013 - 07/2004)
6. Chang, Yusuo: 4 articles (10/2007 - 12/2004)
7. Warshaw, Erin M: 3 articles (11/2015 - 06/2006)
8. Gong, Changyang: 3 articles (02/2015 - 09/2012)
9. Deng, Senyi: 3 articles (02/2015 - 09/2012)
10. Wei, Yuquan: 3 articles (02/2015 - 09/2012)

Related Diseases

1. Lung Injury
10/01/2011 - "These results suggest that improved formulations of lung surfactants are possible and may be useful in reducing some types of surfactant inactivation in treating lung injuries."
10/01/2011 - "In this study, ARDS was developed in rats by intratracheal instillation of LPS and the effect of two types of surfactant (natural vs. synthetic) was examined to determine their potential corrective roles in general, as well as to compare the two surfactants against one another in particular, in endotoxin-induced lung injury. "
03/02/2010 - "This approach and the described platform will enable systematic investigation of the effect of different degrees of fluid mechanical stresses on lung injury at the cellular level and administration of exogenous therapeutic surfactants."
04/01/2001 - "Lung injury was induced in adult rabbits via intratracheal instillation of 0.2 N HCl followed by conventional mechanical ventilation (CMV) until Pa(O2)/FI(O2) values ranged from 220 to 270 mm Hg. Subsequently, animals were given one of three surfactants administered via three different methods and physiological responses were assessed over a 1-h period. "
01/01/2009 - "It is possible that in the next future anti-inflammatory and anti-oxidant properties of exogenous natural surfactants may be improved through their combination with adequate agents with the aim of counteracting the pathogenetic role of inflammatory and oxidative lung injury injuries in the development of brochopulmonary dysplasia."
2. Newborn Respiratory Distress Syndrome
3. Lung Diseases (Lung Disease)
4. Acute Lung Injury
5. Infection

Related Drugs and Biologics

1. beractant (Survanta)
2. calfactant
3. bovine surfactant preparation SF-RI 1
4. Carbon Monoxide
5. Exosurf (Exosurf Neonatal)
6. Edetic Acid (EDTA)
7. Smear Clear
8. IgA receptor (protein B)
9. A 17 (A-17)
10. Detergents (Detergent)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Artificial Respiration (Mechanical Ventilation)
3. Catheters
4. Highly Active Antiretroviral Therapy (HAART)
5. Lung Transplantation