|1.||Au, Jessie L-S: 9 articles (01/2015 - 08/2003)|
|2.||Wientjes, M Guillaume: 9 articles (01/2015 - 08/2003)|
|3.||Zhuang, Shougang: 6 articles (11/2014 - 02/2009)|
|4.||Vogelzang, Nicholas J: 6 articles (06/2006 - 07/2002)|
|5.||Liu, Na: 5 articles (11/2014 - 05/2011)|
|6.||Schnellmann, Rick G: 5 articles (02/2013 - 02/2009)|
|7.||Grever, Michael: 4 articles (07/2012 - 08/2003)|
|8.||Li, Yong: 4 articles (07/2012 - 08/2003)|
|9.||Fu, Freddie H: 4 articles (07/2012 - 08/2003)|
|10.||Huard, Johnny: 4 articles (07/2012 - 08/2003)|
03/01/1994 - "The synergism of DFMO and suramin against an acute infection was improved when suramin was given at the end of the DFMO administration. "
01/01/2015 - "The aim of this study was thus to investigate the antiviral effect of suramin on CHIKV infection and to elucidate the molecular mechanism underlying inhibition using plaque reduction assay, RT-qPCR, western blot analysis, and plaque assay. "
09/01/2015 - "Its approved status makes it worthwhile to explore the use of suramin to prevent and/or treat CHIKV infections. "
01/01/2015 - "Suramin inhibited the early progression of CHIKV infection, due perhaps to interference with virus fusion and binding, which subsequently prevented viral entry. "
01/01/2015 - "Suramin is a symmetric polyanionic naphthylurea that is widely used in the clinical treatment of parasite infections. "
05/01/2008 - "Suramin therapy resulted in a complete regression of tumor macrovessels and a significant reduction of microvessel density. "
01/01/1999 - "Suramin, a polysulfonated naphthylurea, has been shown to be effective in the treatment of several cancers. "
05/01/1997 - "The results establish that suramin is effective in controlling growth in colonic tumor cells and confirms that suramin activity is synergistic with other chemotherapeutics. "
08/16/2005 - "Although it has shown clinical promise in treatment of several cancers, suramin has many undesirable side effects. "
05/15/1994 - "Because tumor growth is angiogenesis dependent, the clinical efficacy of suramin may relate, in part, to angiosuppression."
08/01/1989 - "Six of nine goats with cerebral trypanosomiasis induced by this stock were cured by a single high dose of suramin (50 mg kg-1). "
12/01/2014 - "Suramin has been used previously to treat trypanosomiasis in Africa. "
05/01/2011 - "Suramin is a polysulfonated naphthylurea, which was originally synthesized and designed as a treatment for trypanosomiasis and selected malignancies and metastatic diseases. "
10/01/2006 - "The first reported human case of trypanosomiasis caused by Trypanosoma evansi was treated using suramin. "
05/01/1994 - "Suramin is a polysulfonated naphthylurea developed originally to treat trypanosomiasis. "
11/01/2012 - "Previously, we demonstrated that the anti-fibrotic agent suramin was effective in decreasing fibrosis in mdx muscles. "
09/01/2011 - "In this study, we further assessed the effect of delayed administration of suramin on the progression of tubulointerstitial fibrosis. "
04/05/2014 - "In addition, suramin ameliorated fibrosis and massive hepatic tissue breakdown. "
07/01/2012 - "Suramin treatment initiated at 2 weeks post-injury was observed to promote muscle regeneration and muscle strength, and to decrease fibrosis. "
09/01/2011 - "Delayed administration of suramin attenuates the progression of renal fibrosis in obstructive nephropathy."
|5.||Prostatic Neoplasms (Prostate Cancer)
03/01/2000 - "Androgen deprivation and four courses of fixed-schedule suramin treatment in patients with newly diagnosed metastatic prostate cancer: A Southwest Oncology Group Study."
03/01/1999 - "Recent studies have proved the effect of suramin on prostate cancer. "
01/01/1999 - "In discussions on the utility of suramin our data should be considered as support for continuing the study of suramin in the treatment of advanced, androgen-independent prostate cancer."
11/11/1997 - "Suramin is an experimental antineoplastic agent which is currently being tested in clinical trials for its utility in treating breast and prostate cancer. "
08/01/1997 - "Suramin has demonstrated modest activity against prostate cancer and is being investigated in clinical trials. "
|2.||Melarsoprol (Mel B)
|4.||Intercellular Signaling Peptides and Proteins (Growth Factors)
|7.||Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)
|10.||O-(chloroacetylcarbamoyl)fumagillol (TNP 470)
|2.||Drug Therapy (Chemotherapy)
|3.||Heterologous Transplantation (Xenotransplantation)