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Sulfhydryl Compounds (Thiols)

Compounds containing the -SH radical.
Also Known As:
Thiols; Mercaptans; Compound, Sulfhydryl; Compounds, Mercapto; Compounds, Sulfhydryl; Mercaptan; Mercapto Compounds; Sulfhydryl Compound; Thiol
Networked: 4168 relevant articles (133 outcomes, 532 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Erel, Ozcan: 137 articles (10/2022 - 02/2007)
2. Erel, Özcan: 100 articles (11/2022 - 01/2015)
3. Neselioglu, Salim: 65 articles (10/2022 - 11/2012)
4. Neşelioğlu, Salim: 38 articles (03/2022 - 04/2015)
5. Alisik, Murat: 27 articles (08/2022 - 09/2015)
6. van Goor, Harry: 22 articles (11/2022 - 02/2007)
7. Spitz, Douglas R: 18 articles (12/2020 - 06/2003)
8. Ergin, Merve: 18 articles (04/2020 - 01/2013)
9. Jones, Dean P: 17 articles (09/2014 - 12/2002)
10. Alışık, Murat: 16 articles (01/2021 - 01/2016)

Related Diseases

1. Neoplasms (Cancer)
12/01/2022 - "For example, complete tumor regression can still be achieved even when the dose is halved (2.5 mg/kg), and the maximum tolerable dose is increased by 40 mg/kg. This strategy is expected to provide an applicable tool for the construction of thiol-linked ADCs with improved therapeutic index."
11/06/2023 - "The dissociation of ICG from Au25 SG18 by the hepatic GSH through thiol-exchange reaction and the subsequent hepatobiliary clearance of the detached ICG were slowed down by GSH depletion, which in turn prolonged the blood circulation of intact ICG-Au25 SG18 and enhanced its tumor targeting. "
08/15/1991 - "The combined use of MCB with flow cytometry and conventional GSH assays may help to delineate subpopulations of cells within tumors with different thiol levels."
01/01/2018 - "In this study, we investigated the effects of inhibiting glycolysis and thiol redox metabolism to evaluate them as alternate treatment strategies in these cancers. "
06/15/2017 - "The results obtained from cyclic voltammetry and electrochemical impedance spectroscopy studies showed that the fabricated aptasensor can specifically identify CT26 cells in the concentration ranges of 10-1.0×105cells/mL and 1.0×105-6.0×106 cells/mL, respectively, with a detection limit of 2cells/mL. Applying the thiol terminated aptamer (5TR1) as a recognition layer led to a sensor with high affinity for CT26 cancer cells, compared to control cancer cells of AGS cells, VERO Cells, PC3 cells and SKOV-3 cells. "
2. Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature
3. Ischemia
4. Body Weight (Weight, Body)
5. Wounds and Injuries (Trauma)

Related Drugs and Biologics

1. Antioxidants
2. Proteins (Proteins, Gene)
3. Glutathione (Reduced Glutathione)
4. Enzymes
5. Disulfides
6. Acetylcysteine (Siran)
7. Reactive Oxygen Species (Oxygen Radicals)
8. Ligands
9. Hydrogels
10. Cysteine (L-Cysteine)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Therapeutics
3. Injections
4. Oral Administration
5. Intravenous Administration