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Herpetic Stomatitis

Stomatitis caused by Herpesvirus hominis. It usually occurs as acute herpetic stomatitis (or gingivostomatitis), an oral manifestation of primary herpes simplex seen primarily in children and adolescents.
Also Known As:
Stomatitis, Herpetic; Gingivostomatitides, Herpetic; Herpetic Gingivostomatitides; Herpetic Gingivostomatitis; Herpetic Stomatitides; Oral Herpes Simplex; Simplex, Oral Herpes; Stomatitides, Herpetic; Gingivostomatitis, Herpetic; Herpes Simplex, Oral
Networked: 143 relevant articles (13 outcomes, 11 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Infections
2. Virus Diseases (Viral Diseases)
3. Stomatitis
4. Neoplasms (Cancer)
5. Pain (Aches)

Experts

1. Gorshenina, A P: 3 articles (01/2017 - 01/2008)
2. Kuznetzova, O Yu: 2 articles (01/2018 - 01/2016)
3. Nesterov, O V: 2 articles (01/2018 - 01/2017)
4. Maximovskaya, L N: 2 articles (01/2017 - 01/2016)
5. Epstein, Joel B: 2 articles (08/2016 - 01/2016)
6. Lill, Michael: 2 articles (08/2016 - 01/2016)
7. Rejali, Ali R: 2 articles (08/2016 - 01/2016)
8. Tzachanis, Dimitrios: 2 articles (08/2016 - 01/2016)
9. Zabner, Rachel: 2 articles (08/2016 - 01/2016)
10. Fedorowicz, Zbys: 2 articles (01/2016 - 10/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Herpetic Stomatitis:
1. Acyclovir (Aciclovir)FDA LinkGeneric
2. Antiviral Agents (Antivirals)IBA
3. SuspensionsIBA
4. pentanedioic acid imidazolyl ethanamideIBA
5. Immunoglobulins (Immunoglobulin)IBA
03/01/1989 - "[Use of an immunoglobulin with targeted action for the prevention and treatment of recurrent herpetic stomatitis in children]."
11/01/1979 - "[Salivary secretory immunoglobulins in children with caries and acute herpetic stomatitis]."
05/01/1991 - "Immunoglobulin with a high titer of antiherpetic antibodies (1:640 to 1:1280) was used for the treatment of children with acute and recurrent herpetic stomatitis. "
10/01/2010 - "Reliable evidence for management of oral submucous fibrosis is still limited; amifostine, hydrolytic enzymes, ice chips and Chinese medicine may be effective in preventing oral mucositis for patients with cancer receiving radiotherapy or chemotherapy; the evidence in treating oral mucositis with allopurinol mouthwash, granulocyte macrophage-colony stimulating factor, immunoglobulin or human placentral extract for patients with cancer receiving treatment is weak and unreliable yet; there is evidence that acyclovir is efficacious in prevention and treatment of herpes simplex virus infections in patients being treated for cancer; there is strong evidence that drugs absorbed or partially absorbed from the gastrointestinal tract prevent oral candidiasis in patients receiving treatment for cancer; relapses and adverse effects are common in using beta carotene, lycopene, vitamin A or retinoids to treat oral leukoplakia; only some weak evidence is provided in using cyclosporines, retinoids, steroids or phototherapy for treating oral lichen planus; the evidence about acyclovir for treating primary herpetic gingivostomatitis is insufficient; there is little research evidence for treatment of burning mouth syndrome. "
6. EnzymesIBA
01/01/1998 - "The activities of antioxidant enzymes in the cornea and tears in patients with ophthalmic herpes and in the saliva in those with herpetic stomatitis were assessed. "
07/01/1996 - "Evaluation of a rapid enzyme immunoassay for the detection of herpes simplex virus antigen in children with herpetic gingivostomatitis."
10/01/2010 - "Reliable evidence for management of oral submucous fibrosis is still limited; amifostine, hydrolytic enzymes, ice chips and Chinese medicine may be effective in preventing oral mucositis for patients with cancer receiving radiotherapy or chemotherapy; the evidence in treating oral mucositis with allopurinol mouthwash, granulocyte macrophage-colony stimulating factor, immunoglobulin or human placentral extract for patients with cancer receiving treatment is weak and unreliable yet; there is evidence that acyclovir is efficacious in prevention and treatment of herpes simplex virus infections in patients being treated for cancer; there is strong evidence that drugs absorbed or partially absorbed from the gastrointestinal tract prevent oral candidiasis in patients receiving treatment for cancer; relapses and adverse effects are common in using beta carotene, lycopene, vitamin A or retinoids to treat oral leukoplakia; only some weak evidence is provided in using cyclosporines, retinoids, steroids or phototherapy for treating oral lichen planus; the evidence about acyclovir for treating primary herpetic gingivostomatitis is insufficient; there is little research evidence for treatment of burning mouth syndrome. "
7. CytokinesIBA
8. SteroidsIBA
01/01/1985 - "Evaluation of enhancing factors for herpetic stomatitis suggested a role of cyclosporin A rather than of steroids and a probable relation to preceding CMV infection. "
01/01/1985 - "Out of 80 kidney graft recipients treated with cyclosporin A and low dose steroids 19 (23.8%) developed herpes virus infection and from these 15 (18.8%) herpetic stomatitis. "
10/01/2010 - "Reliable evidence for management of oral submucous fibrosis is still limited; amifostine, hydrolytic enzymes, ice chips and Chinese medicine may be effective in preventing oral mucositis for patients with cancer receiving radiotherapy or chemotherapy; the evidence in treating oral mucositis with allopurinol mouthwash, granulocyte macrophage-colony stimulating factor, immunoglobulin or human placentral extract for patients with cancer receiving treatment is weak and unreliable yet; there is evidence that acyclovir is efficacious in prevention and treatment of herpes simplex virus infections in patients being treated for cancer; there is strong evidence that drugs absorbed or partially absorbed from the gastrointestinal tract prevent oral candidiasis in patients receiving treatment for cancer; relapses and adverse effects are common in using beta carotene, lycopene, vitamin A or retinoids to treat oral leukoplakia; only some weak evidence is provided in using cyclosporines, retinoids, steroids or phototherapy for treating oral lichen planus; the evidence about acyclovir for treating primary herpetic gingivostomatitis is insufficient; there is little research evidence for treatment of burning mouth syndrome. "
9. RetinoidsIBA
10. AntigensIBA

Therapies and Procedures

1. Therapeutics
2. Photochemotherapy (Photodynamic Therapy)
3. Drug Therapy (Chemotherapy)
01/01/1990 - "Reactivation of oral herpes simplex virus (HSV) is very common in patients receiving cytotoxic chemotherapy or bone marrow transplantation. "
03/01/1986 - "The incidence of oral herpes simplex virus infection in patients undergoing cancer chemotherapy."
06/01/2011 - "The impact of oral herpes simplex virus infection and candidiasis on chemotherapy-induced oral mucositis among patients with hematological malignancies."
11/01/2001 - "Mucositis, gingivitis, herpetic stomatitis and candidiasis are a potential source of systemic infection in patients undergoing chemotherapy. "
10/01/2010 - "Reliable evidence for management of oral submucous fibrosis is still limited; amifostine, hydrolytic enzymes, ice chips and Chinese medicine may be effective in preventing oral mucositis for patients with cancer receiving radiotherapy or chemotherapy; the evidence in treating oral mucositis with allopurinol mouthwash, granulocyte macrophage-colony stimulating factor, immunoglobulin or human placentral extract for patients with cancer receiving treatment is weak and unreliable yet; there is evidence that acyclovir is efficacious in prevention and treatment of herpes simplex virus infections in patients being treated for cancer; there is strong evidence that drugs absorbed or partially absorbed from the gastrointestinal tract prevent oral candidiasis in patients receiving treatment for cancer; relapses and adverse effects are common in using beta carotene, lycopene, vitamin A or retinoids to treat oral leukoplakia; only some weak evidence is provided in using cyclosporines, retinoids, steroids or phototherapy for treating oral lichen planus; the evidence about acyclovir for treating primary herpetic gingivostomatitis is insufficient; there is little research evidence for treatment of burning mouth syndrome. "
4. Radiotherapy
09/01/1997 - "Reactivation of oral herpes simplex virus: implications for clinical management of herpes simplex virus recurrence during radiotherapy."
08/01/2010 - "Prevalence of oral herpes simplex virus (HSV) infection in neutropenic patients was higher than in patients treated with radiotherapy for head and neck cancer (49.8% vs. 0%, respectively). "
10/01/2010 - "Reliable evidence for management of oral submucous fibrosis is still limited; amifostine, hydrolytic enzymes, ice chips and Chinese medicine may be effective in preventing oral mucositis for patients with cancer receiving radiotherapy or chemotherapy; the evidence in treating oral mucositis with allopurinol mouthwash, granulocyte macrophage-colony stimulating factor, immunoglobulin or human placentral extract for patients with cancer receiving treatment is weak and unreliable yet; there is evidence that acyclovir is efficacious in prevention and treatment of herpes simplex virus infections in patients being treated for cancer; there is strong evidence that drugs absorbed or partially absorbed from the gastrointestinal tract prevent oral candidiasis in patients receiving treatment for cancer; relapses and adverse effects are common in using beta carotene, lycopene, vitamin A or retinoids to treat oral leukoplakia; only some weak evidence is provided in using cyclosporines, retinoids, steroids or phototherapy for treating oral lichen planus; the evidence about acyclovir for treating primary herpetic gingivostomatitis is insufficient; there is little research evidence for treatment of burning mouth syndrome. "
5. Laser Therapy (Surgery, Laser)