Steroid 12-alpha-Hydroxylase (CYP8B1)
10
relevant articles (0 outcomes,
0 trials/studies)
found for this Bio-Agent
Description:
A liver microsomal cytochrome P450 enzyme that catalyzes the 12-alpha-hydroxylation of a broad spectrum of sterols in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP8B1gene, converts 7-alpha-hydroxy-4-cholesten-3-one to 7-alpha-12-alpha-dihydroxy-4-cholesten-3-one and is required in the synthesis of BILE ACIDS from cholesterol.
Also Known As:
CYP8B1; 12alpha-Hydroxylase; Cytochrome P450 8B1; Cytochrome P450 CYP8B1; Steroid 12-Hydroxylase; Steroid-12-Hydroxylase; Steroid-12-Monooxygenase; Sterol 12 alpha-Hydroxylase; 12 alpha Hydroxylase; 12 alpha-Hydroxylase, Sterol; 12alpha Hydroxylase; Steroid 12 Hydroxylase; Steroid 12 Monooxygenase; Steroid 12 alpha Hydroxylase; Sterol 12 alpha Hydroxylase; alpha-Hydroxylase, Sterol 12; 12-alpha-Hydroxylase; Steroid 12-Monooxygenase; Sterol 12-alpha-Hydroxylase; Steroid, hydrogen-donor:oxygen oxidoreductase (12-alpha-hydroxylating)
Bio-Agent Context: Research Results