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Staphylococcal Protein A (Protein A)

A protein present in the cell wall of most Staphylococcus aureus strains. The protein selectively binds to the Fc region of human normal and myeloma-derived IMMUNOGLOBULIN G. It elicits antibody activity and may cause hypersensitivity reactions due to histamine release; has also been used as cell surface antigen marker and in the clinical assessment of B lymphocyte function.
Also Known As:
Protein A; Protein A, Staphylococcal
Networked: 2549 relevant articles (65 outcomes, 200 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Zimering, Mark B: 12 articles (02/2021 - 11/2002)
2. Waris, Matti: 7 articles (09/2022 - 01/2017)
3. Peltola, Ville: 6 articles (09/2022 - 01/2017)
4. Li, Wei: 6 articles (01/2022 - 03/2011)
5. Wang, Wei: 6 articles (01/2021 - 05/2005)
6. Kim, Hwan Keun: 6 articles (05/2016 - 10/2009)
7. Schneewind, Olaf: 6 articles (05/2016 - 10/2009)
8. Buck, Martin: 6 articles (09/2015 - 06/2002)
9. Li, Jun: 5 articles (10/2017 - 06/2007)
10. Missiakas, Dominique M: 5 articles (05/2016 - 10/2009)

Related Diseases

1. Neoplasms (Cancer)
2. Infections
3. Lymphoma (Lymphomas)
4. Leukemia
5. Heart Failure

Related Drugs and Biologics

1. Immunoglobulin G (IgG)
2. Proteins (Proteins, Gene)
3. Immunoglobulins (Immunoglobulin)
4. Antigen-Antibody Complex (Immune Complex)
5. Biomarkers (Surrogate Marker)
6. Caspase 3 (Caspase-3)
7. Inosine Triphosphate (ITP)
8. Amyloid (Amyloid Fibrils)
9. Immunoglobulin M (IgM)
10. Vaccines

Related Therapies and Procedures

1. Therapeutics
2. Plasma Exchange
3. Drug Therapy (Chemotherapy)
4. Blood Component Removal (Apheresis)
5. Platelet Transfusion (Blood Platelet Transfusions)