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Spinal Stenosis (Stenosis, Spinal)

Narrowing of the spinal canal.
Also Known As:
Stenosis, Spinal; Spinal Stenoses; Stenoses, Spinal
Networked: 1018 relevant articles (120 outcomes, 166 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Pain (Aches)
2. Spondylolisthesis
3. Radiculopathy (Radiculopathy, Cervical)
4. Low Back Pain (Lumbago)
5. Neck Pain (Cervicalgia)

Experts

1. Manchikanti, Laxmaiah: 31 articles (11/2015 - 01/2005)
2. Benyamin, Ramsin M: 16 articles (11/2015 - 01/2007)
3. Pampati, Vidyasagar: 14 articles (06/2015 - 11/2008)
4. Abdi, Salahadin: 13 articles (11/2015 - 01/2005)
5. Hirsch, Joshua A: 13 articles (11/2015 - 07/2003)
6. Falco, Frank J E: 13 articles (01/2015 - 07/2009)
7. Cash, Kimberly A: 12 articles (01/2015 - 11/2008)
8. Singh, Vijay: 11 articles (11/2015 - 01/2007)
9. Datta, Sukdeb: 11 articles (11/2015 - 01/2005)
10. Boswell, Mark V: 10 articles (11/2015 - 07/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Spinal Stenosis:
1. SteroidsIBA
2. Calcitonin (Calcitonin, Eel)FDA LinkGeneric
3. Alprostadil (Muse)FDA LinkGeneric
4. pregabalin (Lyrica)FDA Link
5. gabapentin (Neurontin)FDA LinkGeneric
6. ONO 1206IBA
7. Sodium Chloride (Saline Solution)FDA LinkGeneric
11/01/2009 - "There have not been any randomized trials evaluating the effectiveness of percutaneous adhesiolysis and targeted delivery of local anesthetic, steroid and hypertonic sodium chloride solution in lumbar spinal stenosis. "
11/01/2009 - "With significant pain relief in 76% of patients, percutaneous adhesiolysis utilizing local anesthetic, steroids and hypertonic sodium chloride solution may be effective in patients with chronic function-limiting low back and lower extremity pain with spinal stenosis."
07/01/2013 - "Percutaneous adhesiolysis utilizing local anesthetic steroids and hypertonic sodium chloride solution may be an effective management strategy in patients with chronic posterior neck and upper extremity pain due to cervical central spinal stenosis, although there is no correlation between therapeutic response and the grade of CCS."
01/01/2013 - "Significant relief and functional status improvement as seen in 71% of the 70 patients with percutaneous adhesiolysis utilizing local anesthetic steroids and hypertonic sodium chloride solution may be an effective management strategy in patients with chronic function limiting low back and lower extremity pain with central spinal stenosis after failure of conservatie management and fluoroscopically directed epidural injections."
12/01/1995 - "The results of postoperative epidural administration of saline solution (a placebo), morphine, methylprednisolone, and a combination of morphine and methylprednisolone for the reduction of pain after an operation for spinal stenosis or a herniated intervertebral disc were compared in a prospective, randomized blinded study. "
8. Adrenal Cortex Hormones (Corticosteroids)IBA
9. pamidronate (APD)FDA LinkGeneric
10. Dichlorodiphenyldichloroethane (DDD)IBA

Therapies and Procedures

1. Decompression
2. Laminectomy
3. Injections
4. Epidural Injections
5. Surgical Decompression