Spin Labels

Molecules which contain an atom or a group of atoms exhibiting an unpaired electron spin that can be detected by electron spin resonance spectroscopy and can be bonded to another molecule. (McGraw-Hill Dictionary of Chemical and Technical Terms, 4th ed)

Also Known As:

Networked: 116 relevant articles (1 outcomes, 45 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Tsuda, Kazushi: 3 articles (10/2016 - 01/2011)
2.	Gurachevsky, Andrey: 2 articles (01/2008 - 09/2007)
3.	Muravsky, Vladimir: 2 articles (01/2008 - 09/2007)
4.	Bartosz, Grzegorz: 1 article (03/2020)
5.	Cieniek, Bogumil: 1 article (03/2020)
6.	Naparlo, Katarzyna: 1 article (03/2020)
7.	Sadowska-Bartosz, Izabela: 1 article (03/2020)
8.	Soszynski, Miroslaw: 1 article (03/2020)
9.	Stefaniuk, Ireneusz: 1 article (03/2020)
10.	Deshpande, Hrishikesh: 1 article (09/2016)

Related Diseases

1.	Hemolysis 01/01/1980 - "Since spin labels have been shown to induce hemolytic and morphologic alterations in erythrocytes, conditions for minimizing these alterations were first defined by hemolysis studies and scanning electron microscopy. " 08/01/1986 - "Increasing grinding times caused a decrease in both the crystallinity and zeta potential of the samples, a decrease in percent hemolysis values and a change in the distribution of free and bound spin label populations. " 05/01/1977 - "Hemolysis of human or chicken erythrocytes by Sendai virus causes a change in the structure of the erythrocyte membrane lipid bilayer that can be detected by spin label electron spin resonance. " 02/19/1976 - "Spectra from membranes treated with the protein spin label showed an increased ratio of immobilized to mobile label with increased Ca2+ concentrations at hemolysis. " 05/01/1977 - "Erythrocyte ghosts prepared by osmotic hemolysis and resealed by treatment with Mg2+ or elevated ionic strength exhibit a difference in fluidity between phosphatidylcholine and phosphatidylethanolamine spin labels, although less than that observed in whole cells. "
2.	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 11/15/1984 - "A spin label study of the erythrocyte membrane in mothers and sisters of patients suffering from Duchenne muscular dystrophy." 10/01/1983 - "Electron spin resonance spin label studies of the erythrocyte membrane in Duchenne muscular dystrophy." 08/04/1980 - "A spin label study of the erythrocyte membranes in Duchenne muscular dystrophy." 02/01/1978 - "Saturation transfer electron paramagnetic resonance and the spin label 2-(3-carboxypropyl)-4,4-dimethyl-2-tridecyl-3-oxazolidinyloxyl were used to study erythrocytes from patients with Duchenne muscular dystrophy or Becker syndrome and from age-matched normal boys. " 10/01/1983 - "The membrane organisation of erythrocytes from patients with Duchenne muscular dystrophy (DMD) and from asymptomatic carriers was studied by the electron spin resonance (ESR) spin label technique. "
3.	Huntington Disease (Huntington's Disease) 01/01/1986 - "Spin label study of red blood cell membranes in Huntington's disease." 05/01/1982 - "Several spin-label electron paramagnetic resonance (EPR) studies of red cell membranes appear to show abnormalities in some Huntington disease (HD) patients, but not in others. " 05/01/1982 - "Spin label electron paramagnetic resonance (EPR) studies of Huntington disease erythrocyte membranes." 01/01/1984 - "Electron spin resonance (ESR) studies were carried out with MAL-6 as spin label on erythrocytes from 21 patients with Huntington's disease (HD) and 18 controls. " 02/21/1983 - "Previous electron spin resonance (ESR) studies employing a protein-specific spin label have suggested an alteration in membrane proteins in erythrocytes in Huntington's disease (HD). "
4.	Alzheimer Disease (Alzheimer's Disease) 03/01/1980 - "Spin label and biochemical studies of erythrocyte membranes in Alzheimer's disease." 07/01/1991 - "Platelet membrane fluidity in Alzheimer's disease and multi-infarct dementia: a spin label study." 06/01/1997 - "Oxidatively induced structural alteration of glutamine synthetase assessed by analysis of spin label incorporation kinetics: relevance to Alzheimer's disease." 07/01/1991 - "The membrane fluidity of platelets isolated from 15 patients with probable Alzheimer's disease (AD), 11 patients with probable multi-infarct dementia (MID), and 7 neurologically healthy controls was studied by electron spin resonance (ESR) spectroscopy employing spin label techniques. " 12/01/1998 - "This approach was applied to the study of fibrillar beta-amyloid (Abeta) peptides (the primary component of the plaques of Alzheimer's disease) containing only a single isotopic spin label (13C), by employing the DRAWS (dipolar recoupling with a windowless sequence) technique to measure 13C-13C distances. "
5.	Hereditary Spherocytosis 11/12/1984 - "Our earlier spin label electron paramagnetic resonance (EPR) studies of hereditary spherocytosis (HS) erythrocyte revealed the existence of structural alteration(s) when the membrane is subjected to heat stress. " 09/01/1980 - "The fluidity gradient in erythrocyte membranes in hereditary spherocytosis: a spin label study." 09/01/1980 - "The fluidity gradient and sulphydryl groups in erythrocyte ghost membranes from healthy subjects and from seven patients with hereditary spherocytosis (HS) were studied by spin label techniques. " 11/16/1987 - "A spin-label study of membrane proteins and internal microviscosity of erythrocytes in hereditary spherocytosis." 11/16/1981 - "Detection of erythrocyte membrane protein alterations in hereditary spherocytosis through the use of thermal stress: a spin label study."

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Sulfhydryl Compounds (Thiols)
3.	permanganic acid (permanganate)
4.	Membrane Proteins (Integral Membrane Proteins)
5.	Lipids
6.	Peptides (Polypeptides)
7.	maleimide
8.	Membrane Lipids
9.	Lipid Bilayers (Lipid Bilayer)
10.	Phospholipids (Phosphatides)

Related Therapies and Procedures

1.	Fluid Therapy (Oral Rehydration Therapy)