|1.||Wang, Kevin K W: 15 articles (08/2015 - 12/2005)|
|2.||Hayes, Ronald L: 14 articles (08/2015 - 01/2004)|
|3.||Gallagher, Patrick G: 10 articles (02/2014 - 11/2002)|
|4.||Azuma, Mitsuyoshi: 9 articles (09/2015 - 02/2002)|
|5.||Shearer, Thomas R: 9 articles (09/2015 - 02/2002)|
|6.||Liu, Ming Cheng: 9 articles (08/2015 - 12/2005)|
|7.||Mishra, Lopa: 6 articles (08/2011 - 12/2004)|
|8.||Bodine, David M: 6 articles (08/2009 - 11/2002)|
|9.||Jackson, Mandy: 5 articles (07/2014 - 04/2010)|
|10.||Speicher, David W: 5 articles (02/2014 - 04/2007)|
|1.||Brain Injuries (Brain Injury)
01/01/2015 - "Spectrin 145/150 was increased in the WT cortex at 4 and 24 h after HI, and spectrin 120 increased 24 h after HI, perhaps reflecting greater injury in the WT brain, especially at 24 h when brain injury is more evident. "
07/29/2014 - "Alpha II Spectrin breakdown products in immature Sprague Dawley rat hippocampus and cortex after traumatic brain injury."
08/01/2012 - "In addition, the reduction in spectrin proteolysis without accompanied neocortical neuroprotection suggests the involvement of other factors that are critical for neuronal survival after contusion brain injury."
07/01/2010 - "αII-spectrin breakdown products (SBDPs): diagnosis and outcome in severe traumatic brain injury patients."
08/01/2009 - "Alpha II-spectrin breakdown products serve as novel markers of brain injury severity in a canine model of hypothermic circulatory arrest."
01/01/2013 - "Further investigations revealed spectrin deficiency; the family study demonstrated that the hemolysis was exclusively attributable to HS. "
04/15/1990 - "Comparison with the results of studies of red blood cell membranes with genetically defective or deficient spectrin suggests that a reduction in t 1/2 of 50% is not associated with significant increases in the rate of hemolysis. "
04/01/2014 - "These results suggest that upon pressure treatment of tightly agglutinated erythrocytes, the hemolysis is greatly suppressed, but membrane damages occur such as spectrin denaturation and vesiculation."
02/01/2007 - "Exercise-induced hemolysis reflects alterations in erythrocyte membrane spectrins and occurs particularly in the early phase of an ultraendurance race because of a relative older cell population."
11/01/2001 - "On the other hand, in erythrocytes that are undergoing vesiculation due to spectrin denaturation at 49 degrees C, compression produces smaller vesicles, so that the hemolysis is suppressed."
05/01/2007 - "Culture studies of Plasmodium falciparum in elliptocytes bearing such elliptocytogenic alleles of spectrin showed that these alleles are supplementary genetic factors of malaria resistance in vitro. "
12/01/2015 - "Recent experiments focusing on the malaria-infected RBCs (iRBCs) show that there is a correlation between the elongation of spectrins in the cytoskeletal network and the stiffening of the iRBCs. "
04/02/2009 - "Heterozygous mutant mice, which have wild-type levels of ANK-1 and spectrin in their RBC membranes and normal red cell survival and ultrastructure, exhibit profound resistance to malaria, which is not due to impaired parasite entry into RBC. "
05/01/2007 - "Certain instances of spectrin mutations or polymorphisms have not yet been shown to constitute new factors of innate resistance to malaria in vivo. "
05/01/2007 - "Spectrin-based skeleton in red blood cells and malaria."
03/30/2010 - "Targeted deletion of betaIII spectrin impairs synaptogenesis and generates ataxic and seizure phenotypes."
06/01/2012 - "Recent study has shown that mutations in the alpha-II-spectrin (SPTAN1) gene cause early onset intractable seizures, severe developmental delay, diffuse hypomyelination, and widespread brain atrophy. "
08/17/1999 - "It did produce a highly significant reduction in increased protein nitration, activator protein-1- and NF-kappaB-binding activity, and spectrin proteolysis as well as in neuronal damage resulting from seizure activity in limbic structures. "
06/01/1992 - "The results indicate that the extent of spectrin breakdown observed shortly after KA-induced seizure activity is causally related to the changes in ODC activity and putrescine levels. "
07/08/1996 - "In the present study, we evaluated the spatio-temporal activation of calpain after the onset of seizure activity by immunohistochemistry using an antibody for the spectrin breakdown product (sbdp) generated by calpain-mediated spectrin proteolysis. "
|2.||Caspase 3 (Caspase-3)
|5.||Lipid Bilayers (Lipid Bilayer)
|6.||((1S)- 1- ((((1S)- 1- benzyl- 3- cyclopropylamino- 2,3- di- oxopropyl)amino)carbonyl)- 3- methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester
|7.||NF-kappa B (NF-kB)
|9.||Proteins (Proteins, Gene)
|10.||N- (4'- fluorobutyrophenone)- 4- (4- chlorophenyl)pyridinium (HPP(+))
|2.||Surgical Instruments (Clip)