Solvents

Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)

Also Known As:

Networked: 5202 relevant articles (119 outcomes, 623 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Sainio, Markku: 18 articles (01/2021 - 05/2005)
2.	Pukkala, Eero: 12 articles (12/2019 - 03/2005)
3.	Kaukiainen, Ari: 11 articles (01/2019 - 05/2005)
4.	Stewart, Patricia A: 11 articles (01/2019 - 01/2003)
5.	van der Laan, Gert: 11 articles (10/2018 - 05/2008)
6.	Hansen, Johnni: 10 articles (01/2022 - 07/2014)
7.	Rothman, Nathaniel: 9 articles (10/2022 - 01/2009)
8.	Fuente, Adrian: 9 articles (01/2020 - 07/2006)
9.	Kauppinen, Timo: 9 articles (09/2014 - 01/2002)
10.	Akila, Ritva: 9 articles (08/2012 - 05/2005)

Related Diseases

1.	Neoplasms (Cancer) 11/01/2012 - "We recently developed a highly reproducible and versatile clearing procedure called 3D imaging of solvent-cleared organs, or 3DISCO, which is applicable to diverse tissues including brain, spinal cord, immune organs and tumors. " 02/01/2015 - "For drug nanoencapsulation, a water in oil (W/O) emulsification and solvent evaporation technique was used and the prepared nanoparticles were studied for their physical properties, morphology, drug release and anticancer efficacy against cancer cell lines. " 12/01/2023 - "Using this study, one suitable hydrophobic lead anti-cancer organometallic pharmaceutical was found that binds at the less solvent-accessible hydrophobic site of BCL-2." 05/25/2022 - "While the CS method is here applied to anti-cancer drug-membrane translocation, it could be used more generally to study processes considering solvent effects." 01/01/2021 - "Along with it, the present review also provides information on the ethnomedicinal uses, solvents used for extraction of anti-cancer metabolites, clinical trials, and in silico studies that were undertaken towards anticancer drug development from medicinal mushrooms. "
2.	Breast Neoplasms (Breast Cancer) 01/01/2022 - "This study indicates a positive association between organic solvents and breast cancer." 01/01/2022 - "This study explored the association between organic solvents and breast cancer. " 01/01/2022 - "After stratification by menopause and study location, it was revealed that the association between occupational exposure to organic solvents and the risk of breast cancer in postmenopausal women (OR, 1.35; 95% CI, 1.09 ~ 1.67; I2 = 73.4%; 7 studies) was significant, and there was also a clear association in workers in Europe (OR, 1.21; 95% CI, 1.12 ~ 1.32; I2 = 82.9%; 13 studies). " 01/01/2022 - "The pooled OR of breast cancer among workers exposed to organic solvents overall was 1.18 (95%CI, 1.11 ~ 1.25; I2 = 76.3%; 24 studies), compared to those with no exposure. " 01/01/2022 - "Recent studies suggest that organic solvent exposure could be closely related to breast cancer, although the evidence remains controversial. "
3.	Dehydration (Water Stress) 09/22/2016 - "Upon exposure to moisture followed by dehydration (so-called solvent annealing), these films recrystallized to form larger, highly oriented crystals with fewer electronic defects and a remarkable improvement in photocurrent and photovoltaic efficiency." 09/28/2022 - "However, in the main applications of solvent-type PI adhesives, pinholes or bubbles often exist in the cured PI adhesive layers due to the solvent volatilization and dehydration reaction, which directly affect the adhesive performance. " 01/01/2008 - "To evaluate the efficacy of pubovaginal sling using human cadaveric dermis processed by solvent dehydration and compare results to those of another group in which autograft rectus fascia was used. " 01/01/2011 - "The aim of this study was to investigate the effects of the freeze drying and solvent dehydration allograft preservation methods on the mechanical properties of the graft material. " 11/03/2023 - "This dynamic helicity can be enhanced through selective solvation by increasing the polarity of the organic solvents or simply via their thermally mediated dehydration in water. "
4.	Flushing 07/15/2020 - "For inverted OSCs based on PBDB-TF:IT-4F, the power conversion efficiency (PCE) enhances from 12.87 to 14.05%, and for a PBDB-TF:Y6-based device, the PCE also significantly increases from 15.40 to 16.51% because of greatly enhanced Jsc and FF, benefited from enhanced charge transport and suppressed charge recombination by solvent-flushing. " 12/20/2021 - "By heart-cutting and transporting a selected fraction from the SFC flow into a trapping column with a flushing solvent, re-focusing of the collected analytes can be achieved by re-mobilization with another solvent once the depressurized CO2 is eliminated. " 10/30/2020 - "Efficacy of flushing was influenced by the lipophilicity of drugs but not by either the flushing solvent used or the flushing flow rate. " 07/01/2011 - "This melting and flushing usually demands using the equivalent of a few milliliters of hot solvent, a procedure which although well suited for in vivo studies leads to an excessive sample volume when considering typical analytical settings. " 02/05/2024 - "Results of this field-scale test indicated in-situ microemulsion flushing successfully enhanced the apparent solubility of various chlorinated solvents. "
5.	Infections 01/01/2019 - "High-Resolution 3D Imaging of Rabies Virus Infection in Solvent-Cleared Brain Tissue." 01/01/2022 - "Data obtained from this study collectively indicated that the three solvent extracts of Carissa spinarum have a promising antimicrobial activity which supports the traditional claim of the plant for treatment of infection." 09/29/2023 - "The bioactive extracted using the MAE with water as solvent had minimum inhibitory concentration (MIC) and could suppress infection at 10 mg/disc. " 12/15/2021 - "Upon solvent evaporation, FFG converted in situ into bioadhesive film (81.90 ± 3.24 g) leading to longer residence on skin surface, prolonged delivery and ~1.3 fold enhanced CTZ skin retention as compare to commercial cream as evident from biopharmaceutical analysis, which is ideal for skin infections treatment. " 06/24/2021 - "Although the infected mice in the solvent control died within 10 days after infection, 90% of the mice infected with P. "

Related Drugs and Biologics

1.	Paclitaxel (Taxol)
2.	Detergents (Detergent)
3.	130-nm albumin-bound paclitaxel
4.	Emulsions
5.	Dimethyl Sulfoxide (DMSO)
6.	Albumin-Bound Paclitaxel
7.	Albumins
8.	Lipids
9.	Carboplatin (JM8)
10.	Factor VIII (Coagulation Factor VIII)

Related Therapies and Procedures

1.	Neoadjuvant Therapy
2.	Therapeutics
3.	Drug Therapy (Chemotherapy)
4.	Microspheres (Microsphere)
5.	Liver Transplantation