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Sodium Cyanide

A highly poisonous compound that is an inhibitor of many metabolic processes and is used as a test reagent for the function of chemoreceptors. It is also used in many industrial processes.
Also Known As:
Cyanogran; Cyanide, Sodium; Sodium cyanide (Na(CN))
Networked: 120 relevant articles (3 outcomes, 11 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Solomon, Irene C: 3 articles (05/2005 - 03/2002)
2. Akiyama, Tsuyoshi: 2 articles (12/2021 - 01/2019)
3. Milsom, William K: 2 articles (01/2015 - 04/2005)
4. Li, Yansong: 2 articles (04/2010 - 03/2008)
5. Tsokos, George C: 2 articles (04/2010 - 12/2003)
6. Gilmour, Kathleen M: 2 articles (01/2010 - 04/2005)
7. Perry, Steve F: 2 articles (01/2010 - 04/2005)
8. Akiyama, T: 2 articles (05/2008 - 05/2000)
9. Yamazaki, T: 2 articles (05/2008 - 05/2000)
10. Kiang, Juliann G: 2 articles (03/2008 - 12/2003)

Related Diseases

1. Hypoxia (Hypoxemia)
2. Ischemia
3. Hypercapnia
4. Hypotension (Low Blood Pressure)
01/01/1984 - "The animals in groups 1, 2 and 3 were subjected to continuous infusion of 0.2% sodium cyanide solution and to the ensuing hypotension below 100 mm Hg by administering a ganglion-blocking drug and by respiratory arrest. "
06/01/2017 - "We used a randomized, nonblinded, parallel-group study design in 3 mammalian models: cyanide gas inhalation in mice, with treatment postexposure; intravenous sodium cyanide infusion in rabbits, with severe hypotension as the trigger for treatment; and intravenous potassium cyanide infusion in pigs, with apnea as the trigger for treatment. "
01/01/2003 - "By experiments of acute carbon-monoxide intoxication, acute nitrogen hypoxia and histotoxic hypoxia using sodium cyanide in cats, and by hemodynamic studies using plastic branch models, the following was elucidated; (1) severe tissue hypoxia, regardless of the underlying cause, and subsequent slight ischemia of the brain due to mild hypotension induce selective involvement of the cerebral white matter and pallidum, these two conditions being necessary and sufficient and this encephalopathy should be separately categorized as "hypoxic-ischemic encephalopathy" in hypoxic brain injuries, (2) the background of the selective involvement of these structures is an enormous development of the cerebrum in the brain, which induces thick white matter resulting in proper and long medullary artery, and especially small diameter ratio of the pallidal perforators to the middle cerebral artery, (3) the long course of the medullary artery produces the blood pressure drop in the deep white matter according to Hagen-Poiseuille's low, and according to that the smaller the diameter ratio, the larger the branching-loss coefficient (energy-loss co-efficient), smaller diameter ratio of the pallidal perforator, as compared with that of the putaminal perforator, induces more severe loss of the local blood flow selectively to the pallidum. "
5. Poisoning

Related Drugs and Biologics

1. Chloralose
2. Dialysis Solutions
3. Urethane (Ethyl Carbamate)
4. Myoglobin
5. Muscimol
6. Isoflurane
7. Cyanides (Isocyanides)
8. Oxygen (Dioxygen)
9. Nitrogen
10. Carbon Monoxide

Related Therapies and Procedures

1. Injections
2. Intravenous Injections
3. Intra-Arterial Injections
4. Denervation
5. Artificial Respiration (Mechanical Ventilation)