Sodium Cyanide

A highly poisonous compound that is an inhibitor of many metabolic processes and is used as a test reagent for the function of chemoreceptors. It is also used in many industrial processes.
Also Known As:
Cyanogran; Cyanide, Sodium; Sodium cyanide (Na(CN))
Networked: 106 relevant articles (2 outcomes, 8 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Solomon, Irene C: 3 articles (05/2005 - 03/2002)
2. Milsom, William K: 2 articles (01/2015 - 04/2005)
3. Gilmour, Kathleen M: 2 articles (01/2010 - 04/2005)
4. Perry, Steve F: 2 articles (01/2010 - 04/2005)
5. Li, Yansong: 2 articles (01/2010 - 03/2008)
6. Tsokos, George C: 2 articles (01/2010 - 12/2003)
7. Yamazaki, T: 2 articles (05/2008 - 05/2000)
8. Akiyama, T: 2 articles (05/2008 - 05/2000)
9. Kiang, Juliann G: 2 articles (03/2008 - 12/2003)
10. Brink, Deidre L: 1 article (01/2015)

Related Diseases

1. Anoxia (Hypoxia)
2. Hypercapnia
3. Poisoning
4. Ischemia
01/01/1994 - "Fifteen hearts underwent IPC, consisting of two 5-minute ischemia-reperfusion cycles (IPC group); 18 hearts underwent brief metabolic inhibition by exposure to two 5-minute infusions of 10 mmol/L sodium cyanide (CN group); and 15 hearts served as controls. "
09/12/1997 - "Cultured chick retina cells were submitted to 'chemical ischemia' by metabolic inhibition with sodium cyanide and iodoacetic acid, which block oxidative phosphorylation and glycolysis, respectively. "
06/01/2004 - "Overexpression of hsp10 by adenoviral infection decreased myocyte death induced by hydrogen peroxide, sodium cyanide, and simulated ischemia and reoxygenation (SI/RO). "
10/01/2012 - "For the ex vivo experiments, retinal eye cups were incubated with PBS or the chemical ischemia mixture [iodoacetic acid (5 mM)/sodium cyanide (25 mM)] in the absence or presence of SOM230 (10(-7)-10(-5) M) alone or in the presence of the sst(2) antagonist CYN-154806 (10(-7) or 10(-5) M). "
01/01/2003 - "By experiments of acute carbon-monoxide intoxication, acute nitrogen hypoxia and histotoxic hypoxia using sodium cyanide in cats, and by hemodynamic studies using plastic branch models, the following was elucidated; (1) severe tissue hypoxia, regardless of the underlying cause, and subsequent slight ischemia of the brain due to mild hypotension induce selective involvement of the cerebral white matter and pallidum, these two conditions being necessary and sufficient and this encephalopathy should be separately categorized as "hypoxic-ischemic encephalopathy" in hypoxic brain injuries, (2) the background of the selective involvement of these structures is an enormous development of the cerebrum in the brain, which induces thick white matter resulting in proper and long medullary artery, and especially small diameter ratio of the pallidal perforators to the middle cerebral artery, (3) the long course of the medullary artery produces the blood pressure drop in the deep white matter according to Hagen-Poiseuille's low, and according to that the smaller the diameter ratio, the larger the branching-loss coefficient (energy-loss co-efficient), smaller diameter ratio of the pallidal perforator, as compared with that of the putaminal perforator, induces more severe loss of the local blood flow selectively to the pallidum. "
5. Asphyxia (Suffocation)

Related Drugs and Biologics

1. Carbon Monoxide
2. Chloralose
3. Urethane (Ethyl Carbamate)
4. Myoglobin
5. Muscimol
6. Isoflurane
7. Oxygen
8. Nitrogen
9. Dithionite (Sodium Dithionite)
10. Plastics

Related Therapies and Procedures

1. Injections
2. Intravenous Injections
3. Intra-Arterial Injections
4. Denervation
5. Artificial Respiration (Mechanical Ventilation)