Sodium Chloride (Saline Solution)

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2984 relevant articles (107 outcomes, 261 trials/studies) found for this Drug

Description: A ubiquitous sodium salt that is commonly used to season food. It plays an important biological role in maintaining the osmotic tension of blood and tissues. The OSMOLAR CONCENTRATION this and other SALTS accounts for SALINITY which influences the types of organisms that live in an ENVIRONMENT.

Also Known As:

Saline Solution; Sodium Chloride, (22)Na; Sodium Chloride, (24)NaCl; Sodium chloride (NaCl)

Relationship Network

Drug Context: Research Results

Inorganic Chemicals: 6

Experts

1.	Tekol, Yalcin: 2 articles (01/2008 - 01/2006)
2.	Valeri, C R: 2 articles (11/2000 - 11/2000)
3.	Ragno, G: 2 articles (11/2000 - 11/2000)
4.	Pivacek, L E: 2 articles (11/2000 - 11/2000)
5.	Cassidy, G P: 2 articles (11/2000 - 11/2000)
6.	Reim, Martin: 1 article (11/2008)
7.	Rihawi, Safwan: 1 article (11/2008)
8.	Frentz, Markus: 1 article (11/2008)
9.	Schrage, Norbert Franz: 1 article (11/2008)
10.	Okuyama, Yuji: 1 article (10/2008)

Related Diseases

1.	Neoplasms (Cancer) 05/01/2002 - "Furthermore, a significant reduction in macroscopically visible tumor number with MDM2-AS ODN treatments (100 or 200 microg) in comparison to MDM2-SE ODN or saline solution treatment (both p=0.009) was observed for the first time. " 08/01/1987 - "All groups treated with 2-DG had a significant reduction in tumor weight of 50% to 70% when compared with saline solution-treated controls. " 11/01/1989 - "The oil suspension was more effective in tumor growth delay than was the saline solution. " 07/01/2002 - "Improved coagulation with saline solution pretreatment during radiofrequency tumor ablation in a canine model." 03/01/1999 - "In a study of nude mice with subcutaneous metastatic prostate tumors, we showed that the preoperative injection of a phosphate-buffered saline solution with 10 mg/ml antifreeze protein of type I into the tumor prior to freezing enhances destruction under thermal conditions which normally yield cell survival. " Order ALL the reference details at left...
2.	Wounds and Injuries (Trauma) 05/01/2003 - "STUDY OBJECTIVE: Irrigation, a critical component of wound management, is commonly performed with sterile normal saline solution. " 02/01/2000 - "The second trial controlled for the trauma associated with the surgical procedure by applying 0.9% saline solution in lieu of BC in four turkeys. " 03/01/2009 - "One week after inducing an open crush trauma in 34 female Sprague Dawley rats, increasing quantities of autologous MSCs (0.1 x 10(6), 1 x 10(6), 2.5 x 10(6), and 10 x 10(6) cells) or saline solution (control group) were transplanted into the left soleus muscle of the rat hind limb. " 01/01/2009 - "CONCLUSIONS: Approaches used to remove bacteria from wounds, such as irrigants other than saline solution or high-pressure devices, may not have the best clinical outcome." 01/01/2009 - "BACKGROUND: The saline solution load test helps to determine if a wound extends into the knee joint. " Order ALL the reference details at left...
3.	Hemorrhagic Shock 12/01/1986 - "Hypertonic sodium chloride solutions for the prehospital management of traumatic hemorrhagic shock: a possible improvement in the standard of care?" 07/01/1992 - "This experiment was performed to study the effects of administration of 20% saline solution 1.5 ml.kg-1 on the circulatory dynamics during the hemorrhagic shock state. " 01/01/2006 - "CONCLUSION: Both critical situations in this model, controlled hemorrhagic shock followed by Pringle's maneuver, promoted neutrophils sequestration in the interstitium renal of rat, and the physiologic saline solution demonstrated minor mean, differentiating statistically of the others solutions." 01/01/2004 - "Animals in the s+c group were randomized to receive an intravenous bolus of C5aR antagonist at 1 mg/kg or saline solution control at the end of hemorrhagic shock. " 01/01/1995 - "Hemorrhagic shock was induced using a fixed pressure (mean arterial pressure, 40 mm Hg) model and resuscitated with either saline solution or heparan. " Order ALL the reference details at left...
4.	Body Weight (Weight, Body) 08/01/2006 - "OBJECTIVE: The purpose of this study was to investigate, first, the effect on enhancement of the liver and aorta during abdominal CT of the use of saline solution as a partial substitute for or in addition to contrast medium when the dose of medium is determined by the patient's body weight and, second, whether use of a saline chaser allows a decrease in the dose of contrast medium to less than 1.5 mL/kg. SUBJECTS AND METHODS: We enrolled 407 patients undergoing abdominal exploration on MDCT, including an early arterial phase and a portal phase. " 09/01/2002 - "Intestinal washings with saline solution (1% body weight), fecal samples, and organ scrapings were collected during the study. " 07/01/1994 - "STUDY DESIGN: Rats received a permanent jugular vein cannula on day 0 of pregnancy, through which endotoxin (1.0 micrograms/kg body weight) (n = 10) or saline solution (n = 6) was infused during 1 hour on day 14 of pregnancy. " 05/01/1994 - "Ponies were selected then allocated at random and in equal numbers to 2 groups that received 1 of 2 treatments prior to induction of large-colon torsion: group 1--control (saline solution), and group 2--WEB 2086 (3 mg/kg of body weight loading dose and 3 mg/kg/h for the remainder of the study). " 10/01/1993 - "The present study compared the postweaning blood pressures and body weights of borderline hypertensive rats exposed to a high (8%) sodium chloride maternal diet either from conception to weaning or only during the weaning period with borderline hypertensive rats consistently exposed to a normal (1%) sodium chloride maternal diet. " Order ALL the reference details at left...
5.	Pain (Aches) 10/01/2009 - "Group I patients who received intravenous and peritonsillar saline solution as placebo had higher pain scores at 15th min, and 1st and 4th h than group II, and at all time intervals, than group III (P<0.05). " 01/01/2008 - "PURPOSE: to compare diagnostic hysteroscopy through vaginoscopy, using warm saline solution, with traditional technique, regarding to pain, patient satisfaction and feasibility of the procedure. " 01/01/2007 - "P 1.3 mg x kg-l (group 1), P 0.8 mg x kg-l (group 2) and sodium chloride 0,9% (group 3) and we registered the motility, the pain reaction to electrical and mechanical nociceptive stimuli, the respiratory rate and amplitude, electrocardiogram, heart rate, mean arterial blood pressure electroencephalogram and, for 2 subjects from group 1, electromyogram. " 12/01/2003 - "The purpose of this double-blind study was to evaluate the effects of iontophoresis with dexamethazone to iontophoresis with saline solution on patients who had acute (less than 3 months) pain from the Achilles tendon, in terms of range of motion, muscular endurance, pain and symptoms. " 03/01/1999 - "CONCLUSION: Intradermal unpreserved saline solution contributes to greater pain intensity and distress, greater insertion difficulty, and a higher failure rate than the use of music or routine IV insertion. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Sodium Bicarbonate (Baking Soda)
2.	Dextrans (Dextran)
3.	Potassium
4.	crystalloid solutions
5.	Glucose (Dextrose)
6.	Calcium
7.	Lidocaine (Xylocaine)
8.	Urea (Carbamide)
9.	Renin
10.	Mannitol (Osmitrol)

Related Therapies and Procedures

1.	Induced Heart Arrest (Cardioplegia)
2.	Injections
3.	Intravenous Infusions
4.	Drug Therapy (Chemotherapy)
5.	Baths

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