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Sjogren's Syndrome (Sjogren Syndrome)

Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.
Also Known As:
Sjogren Syndrome; Syndrome, Sicca; Sjogrens Syndrome; Syndrome, Sjogren's; Sicca Syndrome
Networked: 1409 relevant articles (55 outcomes, 134 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Dry Eye Syndromes (Dry Eye Syndrome)
2. Xerostomia
3. Inflammation (Inflammations)
4. Oral Lichen Planus
5. Xerophthalmia

Experts

1. Moutsopoulos, Haralampos M: 14 articles (02/2021 - 06/2002)
2. Mavragani, Clio P: 12 articles (02/2022 - 06/2007)
3. Tzioufas, Athanasios G: 11 articles (02/2021 - 06/2002)
4. Suresh, Lakshmanan: 9 articles (03/2017 - 12/2012)
5. Ambrus, Julian L: 8 articles (03/2017 - 12/2012)
6. Malyavantham, Kishore: 8 articles (03/2017 - 12/2012)
7. Shen, Long: 8 articles (03/2017 - 12/2012)
8. Nezos, Adrianos: 7 articles (02/2022 - 06/2014)
9. Sakarellos, Constantinos: 7 articles (09/2008 - 06/2002)
10. Sakarellos-Daitsiotis, Maria: 7 articles (09/2008 - 06/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Sjogren's Syndrome:
1. Rituximab (Mabthera)FDA Link
2. Immunoglobulin A (IgA)IBA
3. Hydroxychloroquine (Plaquenil)FDA LinkGeneric
4. SS-B antibodiesIBA
5. LipidsIBA
6. cevimeline (Evoxac)FDA Link
7. CholesterolIBA
8. SteroidsIBA
9. Pilocarpine (Ocusert)FDA LinkGeneric
10. Lubricant Eye Drops (Artificial Tears)IBA

Therapies and Procedures

1. Therapeutics
2. Immunotherapy
3. Aftercare (After-Treatment)
4. Radiotherapy
5. Resistance Training