|4.||Asthma (Bronchial Asthma)
|1.||Wormald, Peter-John: 13 articles (03/2014 - 12/2004)|
|2.||Borish, Larry: 13 articles (10/2013 - 04/2002)|
|3.||Steinke, John W: 12 articles (10/2013 - 02/2003)|
|4.||Wald, Ellen R: 9 articles (01/2014 - 11/2002)|
|5.||Brook, Itzhak: 9 articles (11/2011 - 04/2004)|
|6.||Ferguson, Berrylin J: 8 articles (04/2012 - 06/2004)|
|7.||Hwang, Peter H: 7 articles (12/2013 - 10/2002)|
|8.||Keating, Gillian M: 7 articles (01/2005 - 01/2002)|
|9.||Zhanel, George G: 6 articles (10/2014 - 01/2002)|
|10.||Lee, Sang Hag: 6 articles (05/2014 - 02/2002)|
|1.||Anti-Bacterial Agents (Antibiotics)IBA
01/01/2008 - "We examined whether antibiotics are effective in treating acute sinusitis, and if so, which antibiotic classes are the most effective. "
11/01/2015 - "Sinusitis is a very common disease and improved diagnostic tools are desirable also in view of reducing over-prescription of antibiotics. "
02/01/2015 - "Both patients' symptoms resolved completely after approximately 1 month of oral antibiotics for sinusitis. "
01/01/2010 - "The addition of INCSs to oral antibiotics has been proven to be more effective than antibiotics alone for achieving symptomatic improvement in patients with acute rhino sinusitis. "
12/01/1996 - "Antibiotics remain the primary therapeutic agent of choice in pediatric sinusitis, with other therapeutic modalities having little proven efficacy."
|2.||Amoxicillin (Wymox)FDA LinkGeneric
11/01/2014 - "High-dose amoxicillin with saline nasal irrigation relieved acute sinusitis symptoms faster and more often than saline nasal irrigation alone. "
01/01/1995 - "Our results indicate that 1000 mg amoxicillin administered twice daily produces tissue concentrations high enough to be clinically effective in patients with either acute or chronic sinusitis."
11/01/2014 - "A comparison of the efficacy of amoxicillin and nasal irrigation in treatment of acute sinusitis in children."
11/01/2014 - "This study aimed to compare the efficacies of amoxicillin with nasal irrigation and nasal irrigation alone for acute sinusitis in children. "
07/01/2013 - "Care patterns for the medical treatment of acute adult sinusitis have changed after guideline publication, with an increase in oral antibiotic prescription rates in cases of acute sinusitis and increase in the use of amoxicillin as the first-line antimicrobial agent. "
|3.||Adrenal Cortex Hormones (Corticosteroids)IBA
12/01/2015 - "Intranasal corticosteroids (INS) have been proven effective in controlling postnasal drip, decreasing inflammatory response, reducing nasal swelling, and increasing aeration of the sinuses such that INS are recommended as treatment of sinusitis. "
01/01/2011 - "High quality trials assessing the efficacy of systemic corticosteroids both as an adjuvant and a monotherapy in primary care patients with acute sinusitis should be initiated."
11/01/2004 - "Nasal corticosteroids also may be beneficial in treating chronic sinusitis. "
03/24/2015 - "Oral corticosteroids as monotherapy are not associated with improved clinical outcomes in adults with clinically diagnosed acute sinusitis."
01/01/2013 - "We examined whether intranasal corticosteroids (INCS) are effective in relieving symptoms of acute sinusitis in adults and children. "
06/01/1997 - "Low-dose and long-term administration of 14-lactone-ring macrolides (macrolide therapy) has been reported to be very effective in the treatment of chronic sinusitis, including the sinobronchial syndrome. "
07/01/2006 - "I administered macrolides antimicrobial agent to the 2 acute pediatric sinusitis cases and attained good outcomes without recurrence. "
12/01/1999 - "In the other patients, medical therapy, mainly long-term treatment with low doses of macrolides, now regarded as a standard regimen for intractable chronic sinusitis in Japan, was effective in alleviating symptoms regardless of the cause."
01/01/2010 - "[New macrolides or a promise for noninvasive treatment in patients with acute bacterial sinusitis]."
01/01/1996 - "We performed an immunohistological study of subepithelial inflammatory cells in the paranasal mucosa from the patients of chronic sinusitis treated with low-dose, long-term administration of macrolides, and obtained the following results. "
|5.||moxifloxacin (Avelox)FDA Link
01/01/2004 - "Moxifloxacin is a very effective and safe treatment for patients with acute sinusitis in general practice and is highly regarded by both physicians and patients because of rapid symptom improvement and good tolerability."
04/01/2000 - "Three comparative, prospective, randomized, double-blind studies in the treatment of community acquired sinusitis, AECB and CAP demonstrated equal or higher efficacy of moxifloxacin in comparison to standard antibiotic therapies."
01/01/2004 - "Efficacy and tolerability of moxifloxacin in patients with sinusitis treated in general practice : results of a post-marketing surveillance study."
05/01/2002 - "A pharmacokinetic study was carried out to determine moxifloxacin concentrations in sinus tissue, after oral moxifloxacin 400 mg once daily for 5 days to patients with chronic sinusitis, undergoing elective sinus surgery. "
07/01/2013 - "Data were used from a phase III clinical trial designed to evaluate the efficacy and safety of moxifloxacin 400 mg once daily for 5 consecutive days in the treatment of acute bacterial sinusitis. "
|6.||Erythromycin (Erycette)FDA LinkGeneric
06/01/1994 - "Low-dose and long-term administration of erythromycin (EM therapy) has been reported to be very effective for patients with intractable chronic sinusitis including sinobronchial syndrome. "
05/01/2002 - "The present study suggests that long-term, low-dose treatment with erythromycin is effective in persistent chronic sinusitis that does not respond to sinus surgery or systemic steroid/antibiotic treatment. "
01/01/1996 - "Long-term erythromycin therapy has been reported as effective in the treatment of various chronic respiratory diseases, including chronic sinusitis. "
05/01/2002 - "In 17 patients with chronic sinusitis persistent after sinus surgery, long-term, low-dose erythromycin therapy was tested. "
01/01/2001 - "The anti-inflammatory effect of erythromycin and its derivatives, with special reference to nasal polyposis and chronic sinusitis."
01/01/2011 - "Long-term macrolide therapy is an effective treatment for chronic sinusitis and diffuse panbronchiolitis. "
01/01/2005 - "Diffuse panbronchiolitis (DPB) is a progressive inflammatory disease, well recognized in Japan, that is characterized by chronic sinusitis and obstructive small airway disease. "
02/01/1995 - "They also suggest that the patients with chronic sinusitis may be seen as a mild or incomplete type of diffuse panbronchiolitis."
02/01/1995 - "These results indicate that patients with chronic sinusitis only and those with diffuse panbronchiolitis have similar genetic background. "
02/01/1995 - "In the diffuse panbronchiolitis group, 50% of families suffered from chronic sinusitis, in contrast to 18.9% of families in the control group. "
|8.||Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric
01/01/2010 - "Amoxicillin/potassium clavulanate is effective treatment for acute bacterial sinusitis in children."
04/01/2003 - "In a randomized double-blind trial 251 adults with sinusitis-like symptoms were given amoxicillin/clavulanate or placebo for 6 days. "
10/01/1999 - "We carried out clinical and bacteriological studies on clavulanic acid/amoxicillin and amoxicillin in pediatric sinusitis at 11 general practice settings. "
10/01/1999 - "[A clinicobacteriologic study on clavulanic acid/amoxicillin in pediatric sinusitis]."
12/01/2013 - "Current guidelines recommend that acute bacterial sinusitis be treated with amoxicillin-clavulanate. "
|9.||cefuroxime axetil (Ceftin)FDA LinkGeneric
09/01/1996 - "A study of the efficacy of cefuroxime axetil was conducted for the treatment of acute sinusitis in childhood. "
09/01/1998 - "were compared with those of cefuroxime axetil (CA) 250 mg b.i.d., each given for 10 days, in a nationwide, open, prospective, randomized trial of 1414 adults with acute sinusitis. "
02/01/1994 - "A review of all clinical data published to date demonstrates that cefuroxime axetil has been evaluated in the treatment of acute sinusitis and acute exacerbations of chronic sinusitis ("acute-on-chronic sinusitis") in 18 clinical trials involving 1516 assessable patients. "
09/01/2005 - "A 10-d course of cefuroxime axetil offered no clinical benefit to children with an acute respiratory illness and imaging evidence of acute sinusitis."
09/01/1996 - "It was found that cefuroxime axetil was efficaceous for the treatment of sinusitis in childhood."
|10.||Nasal Decongestants (Decongestants)IBA
05/01/1996 - "The results of this study suggest that the administration of decongestants may cause ciliary loss with subsequent sinusitis."
03/01/2011 - "Compared with AR subjects with no SHS exposure, subjects with AR and SHS were more likely to report a family history of chronic sinusitis (p = 0.04) and use nasal decongestants (p = 0.012). "
10/01/2002 - "The initial management of acute sinusitis should be directed toward the relief of symptoms with a 7-day course of decongestants and mucoevacuents. "
08/01/1996 - "Proper therapy, with antimicrobial and decongestants combined when indicated with surgical drainage and correction of pathology, constitutes the cornerstone of management of sinusitis."
07/01/1996 - "The treatment of sinusitis is based on the removal of all nasal tubes, topical decongestants, and maxillary sinus drainage and lavage. "
10/01/2008 - "All studies showed that sinusitis symptoms or outcomes improved in half or more patients after adenoidectomy. "
05/01/1989 - "Overall, adenoidectomy appeared effective in reducing the incidence of OME and sinusitis, and in improving the active ventilatory function of the ET without causing changes in the tubal passage. "
01/01/1988 - "In addition, adenoidectomy improved nasal sinusitis, and in such patients, their active tubal function was satisfactory. "
06/01/2008 - "Adenoidectomy is effective treatment for sinusitis in children."
01/01/1997 - "These findings may indicate that adenoidectomy is effective for sinusitis in children."
02/01/2013 - "After treatment, the total sinusitis symptom score improved from 12 to 0 and the CT scan showed almost complete disease resolution. "
02/01/2012 - "After treatment, both groups improved significantly on the Sinusitis Symptoms Score. "
10/01/2014 - "After treatment, the sense of smell was restored in all cases with a concomitant improvement in sinusitis as confirmed by computerized tomography. "
07/01/2000 - "We studied the association between the severity of pretreatment CT scan findings and the improvement in symptoms of chronic sinusitis after treatment. "
01/01/1984 - "The course of the GN may be improved after treatment of the sinusitis and the allergic disposition. "
|3.||Drug Therapy (Chemotherapy)
04/01/2003 - "[Efficacy of combined drug therapy using a macrolide antibiotic and an antihistamine for adult patients with chronic paranasal sinusitis]."
08/01/2013 - "Management of invasive fungal sinusitis includes both surgery and antifungal chemotherapy. "
01/01/2006 - "We report a case of sinusitis due to Absidia corymbifera occurring during chemotherapy-induced bone marrow aplasia in a patient with acute leukaemia. "
04/01/2000 - "Pharmacotherapy of acute sinusitis in children."
04/01/1990 - "Three cases of fulminant fungal sinusitis in patients undergoing intensive chemotherapy for haematological malignancies are described. "
05/01/2010 - "Allergic fungal sinusitis was recently further classified using a radiologic staging system and was proven to have symptomatic improvement with the concomitant use of surgery and immunotherapy. "
12/01/2012 - "However, because the number of patients treated has been small and one study suggested that fungal immunotherapy administered before removal of fungal contents from the sinuses could worsen sinusitis, controlled studies are essential to moving forward."
10/01/1997 - "Nevertheless, an even longer period of study will be necessary to provide the final answer regarding the role of immunotherapy in the treatment of allergic fungal sinusitis."
10/01/2015 - "Sublingual Immunotherapy for Allergic Fungal Sinusitis."
01/01/2013 - "Immunotherapy in allergic fungal sinusitis: The controversy continues. "
04/01/2015 - "The aim of this study was to determine the usefulness of routine sinonasal evaluation before LT and pre-transplant treatment of sinusitis. "
03/01/2015 - "The objective of this study was to evaluate pretransplant sinus computed tomography (CT) as predictor of post-hematopoietic stem cell transplant sinusitis. "
08/01/2015 - "The results were overwhelmingly positive, with 17 of 19 buccal advancement flaps showing no dehiscence or chronic sinusitis and all 24 buccal fat pad grafts showing no dehiscence, with no continued sinus complaints. "
08/01/2015 - "Forty-three patients with chronic sinusitis from 2007 to 2013 were evaluated after combined functional endoscopic sinus surgery and closure of oroantral communication with a buccal fat pad graft or buccal advancement flap for persistent oroantral communication. "
01/01/2014 - "The risk for postoperative rhinosinusitis was found to be higher in patients who suffer from chronic sinusitis and in cases in which a large amount of graft was utilized for sinus lifting. "