|1.||Kligerman, A D: 2 articles (11/2000 - 02/2000)|
|2.||Tennant, A H: 2 articles (11/2000 - 02/2000)|
|3.||Doerr, C L: 2 articles (11/2000 - 02/2000)|
|4.||Iyer, Poorni: 1 article (08/2014)|
|5.||Silva, Marilyn: 1 article (08/2014)|
|6.||Bae, Jeehyeon: 1 article (01/2012)|
|7.||Park, Ho-Oak: 1 article (01/2012)|
|8.||Li, Weiwei: 1 article (09/2011)|
|9.||Peng, Hong: 1 article (09/2011)|
|10.||Chen, Shiheng: 1 article (09/2011)|
|2.||Chromosome Aberrations (Chromosome Abnormalities)
11/20/2000 - "Although there are several contradictory genotoxicity studies in the literature, our previous in vitro studies with human lymphocytes showed that atrazine, simazine, and cyanazine did not induce sister chromatid exchanges (SCEs) or chromosome aberrations (CAs) up to the limits of solubility in aqueous medium using 0.5% dimethyl sulfoxide. "
02/16/2000 - "Because of this and the prevalence of contradictory cytogenetic studies in the literature on atrazine, simazine, and cyanazine, a series of in vitro experiments was performed to investigate the ability of these three triazines to induce sister chromatid exchanges (SCEs) and chromosome aberrations (CAs) in human lymphocyte cultures. "
08/01/2014 - "Fetal developmental delays, endocrine disruption, and mammary tumors resulted from simazine treatment. "
08/01/2014 - "Simazine causes neuroendocrine disruption and mammary cancer in test animals. "
04/01/2011 - "Chronic studies of atrazine and simazine and their common metabolites show an elevated incidence of mammary tumors only in female Sprague Dawley (SD) rats. "
09/01/1999 - "Although they possess a very low acute toxicity in animals, a mammary tumor response has been consistently observed in Sprague-Dawley (SD) female rats following chronic oral dosing of atrazine and simazine at and above maximum tolerated doses. "
11/01/2000 - "Chloro-S-triazine herbicides [cyanazine (CZ), atrazine (AZ), simazine (SZ)] increase mammary tumors in Crl:CD BR rats but not in F-344 rats or in mice. "
|4.||Body Weight (Weight, Body)
01/01/2012 - "In the present study, pregnant mice were orally exposed to low doses (0, 5, 50, or 500 µg/kg body weight per day) of simazine during gestation and lactation, during which no overt maternal toxic response was detected, and their offspring was assessed. "
06/27/2003 - "Body weight and spleen and thymus weight decreased generally in simazine-treated mice, while the weight of adrenal glands was higher than in the control. "
10/01/1994 - "A maximum tolerated dose (MTD: > or = 10% body weight reduction) was estimated to be 100 mg/kg for atrazine and 300 mg/kg for simazine for both stains. "
06/27/2003 - "Male C57Bl/6 mice were treated with vehicle or 300 or 600 mg/kg body weight (bw) simazine daily orally for 4 wk. The immune system was evaluated by the antibody response to sheep red blood cells (SRBC; plaque assay and serum immunoglobulin G), natural killer (NK) and macro-phage activities, lymphocyte subpopulations in the spleen and thymus, and concanavalin A (Con A)- and lipopolysaccharide (LPS)-stimulated lymphocyte proliferation using splenocytes. "
|5.||Prostatic Neoplasms (Prostate Cancer)
02/01/2011 - "The significant association between prostate cancer risk and exposure to DDT (OR = 1.68; 95% CI: 1.04-2.70 for high exposure), simazine (OR = 1.89; 95% CI: 1.08-3.33 for high exposure), and lindane (OR = 2.02; 95% CI: 1.15-3.55 for high exposure) is in keeping with those previously reported in the literature. "
06/01/2011 - "In comparison with unexposed persons, increased risks of prostate cancer were observed among persons exposed to compounds which may have prostate-specific biologic effects (methyl bromide (odds ratio = 1.62, 95% confidence interval: 1.02, 2.59) and a group of organochlorines (odds ratio = 1.64, 95% confidence interval: 1.02, 2.63)) but not among those exposed to other compounds that were included as controls (simazine, maneb, and paraquat dichloride). "
03/01/2003 - "We concluded that Hispanic farm workers with relatively high levels of exposure to organochlorine pesticides (lindane and hepatachlor), organophosphate pesticides (dichlorvos), fumigants (methyl bromide), or triazine herbicides (simazine) experienced elevated risk of prostate cancer compared to workers with lower levels of exposure."
|4.||Dimethyl Sulfoxide (DMSO)
|8.||methyl bromide (bromomethane)
|9.||Vitamin A (Retinol)