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Siderosis

A form of pneumoconiosis resulting from inhalation of iron in the mining dust or welding fumes.
Also Known As:
Sideroses
Networked: 564 relevant articles (20 outcomes, 50 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. beta-Thalassemia (Cooley's Anemia)
2. Sensorineural Hearing Loss
3. Heart Failure
4. Cardiac Arrhythmias (Arrythmia)
5. Syringomyelia (Morvan's Disease)

Experts

1. Pennell, Dudley J: 14 articles (03/2015 - 05/2006)
2. Porter, John B: 7 articles (06/2015 - 03/2010)
3. Aydinok, Yesim: 6 articles (06/2015 - 03/2010)
4. Cappellini, Maria Domenica: 6 articles (11/2014 - 02/2002)
5. Galanello, Renzo: 6 articles (06/2013 - 05/2006)
6. Habr, Dany: 5 articles (06/2015 - 03/2010)
7. Kattamis, Antonis: 5 articles (06/2015 - 01/2005)
8. El-Beshlawy, Amal: 5 articles (06/2015 - 03/2010)
9. Piga, Antonio: 5 articles (02/2015 - 05/2006)
10. Musallam, Khaled M: 5 articles (02/2015 - 01/2011)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Siderosis:
1. IronIBA
2. deferiprone (CP20)IBA
3. Ferritins (Ferritin)IBA
4. Glucose (Dextrose)FDA LinkGeneric
01/01/2010 - "Significant reduction in signal intensity ratio (SIR) of the liver and the pancreas was shown in thalassemic patients compared to controls (P < 0.0001), Thalassemic patients with abnormal glucose tolerance; including diabetics and thalassemics with impaired glucose tolerance; displayed a higher degree of pancreatic and hepatic siderosis compared to thalassemics with normal glucose tolerance or controls (P < 0.001, P < 0.0001). "
01/01/2010 - "pancreatic siderosis can be detected by T2* gradient-echo MRI since childhood in thalassemic patients, and is more evident in patients with abnormal glucose tolerance. "
06/01/2007 - "The study aims at describing the MR features of pancreas in beta-thalassemia major, investigating the relations between MR findings and glucose disturbances and between hepatic and pancreatic siderosis. "
01/01/2013 - "All patients showed significant reduction in the signal intensity of the liver and the pancreas on T2(∗)GRD compared to controls, thalassemic patients who had abnormal glucose tolerance; diabetic and impaired glucose tolerance patients displayed a higher degree of pancreatic and hepatic siderosis and more T2(∗) drop in their signal intensity than those with normal blood sugar level. "
03/01/2010 - "Iron accumulation predominantly in hepatocyes was associated with a 1.7-fold higher risk of a fibrosis stage greater than 1 (95% confidence interval [CI]: 1.2-2.3), compared with the absence of siderosis (after adjustment for age, body mass index, glucose tolerance status, and alanine aminotransferase level). "
5. Deferoxamine (Desferal)FDA LinkGeneric
6. HemosiderinIBA
7. Isoflurophate (DFP)FDA Link
8. Interferon-alpha (Interferon Alfa)FDA Link
9. Biological Markers (Surrogate Marker)IBA
10. tau Proteins (tau Protein)IBA

Therapies and Procedures

1. Chelation Therapy (Therapy, Chelation)
2. Cochlear Implantation
3. Gastric Bypass (Roux-en-Y Gastric Bypass)
4. Lasers (Laser)
5. Cochlear Implants (Cochlear Implant)