Shy-Drager Syndrome

120  relevant articles (3 outcomes, 5 trials/studies) found for this Disease

Dysautonomia-Orthostatic Hypotension Syndrome; Syndrome, Dysautonomia-Orthostatic Hypotension; Autonomic Failures, Progressive; Dysautonomia Orthostatic Hypotension Syndrome; Dysautonomia-Orthostatic Hypotension Syndromes; Dysautonomic Orthostatic Hypotension; Dysautonomic Orthostatic Hypotensions; Failure, Progressive Autonomic; Failures, Progressive Autonomic; Hypotension Syndrome, Dysautonomia-Orthostatic; Hypotension Syndromes, Dysautonomia-Orthostatic; Hypotension, Dysautonomic Orthostatic; Hypotensions, Dysautonomic Orthostatic; Idiopathic Orthostatic Hypotension, Shy Drager Type; Orthostatic Hypotensions, Dysautonomic; Progressive Autonomic Failure; Progressive Autonomic Failures; Shy Drager Syndrome; Syndrome, Dysautonomia Orthostatic Hypotension; Syndrome, Shy-Drager; Syndromes, Dysautonomia-Orthostatic Hypotension; Autonomic Failure, Progressive; Idiopathic Orthostatic Hypotension, Shy-Drager Type; Orthostatic Hypotension, Dysautonomic

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Orthostatic Hypotension (Postural Hypotension)
2.	Multiple System Atrophy
3.	Parkinson Disease (Parkinson's Disease)
4.	Syndrome
5.	Hypertension (High Blood Pressure)

Experts

1.	Shigematsu, Kenji: 1 article (07/2005)
2.	Higa, Kazuo: 1 article (07/2005)
3.	Shono, Shinjiro: 1 article (07/2005)
4.	Hamada, Takamitsu: 1 article (07/2005)
5.	Vallejo, Ricardo: 1 article (07/2002)
6.	DeSouza, Gerard: 1 article (07/2002)
7.	Lee, Jong: 1 article (07/2002)
8.	Hanaoka, K: 1 article (01/2001)
9.	Hashimoto, H: 1 article (01/2001)
10.	Nakajima, H: 1 article (01/2001)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Shy-Drager Syndrome:

1.	Propranolol (Inderal)FDA LinkGeneric 11/01/1981 - "Effective treatment of orthostatic hypotension by propranolol in the Shy-Drager syndrome." 05/01/1982 - "Indomethacin and propranolol combined treatment for Shy-Drager syndrome." 01/01/1986 - "Shy-Drager syndrome: description of a clinical case which failed to respond to propranolol, ergotamine and indomethacin]" Order ALL the reference details at left...
2.	Midodrine (Midon)FDA LinkGeneric 06/01/1993 - "Therefore, a recent multicenter study evaluated the safety and efficacy of midodrine therapy in 97 patients with neurogenic orthostatic hypotension due to various etiologies: Shy Drager syndrome (No. 18); Bradbury Eggleston syndrome (idiopathic orthostatic hypotension) (No. 20); diabetic autonomic neuropathy (No. 27); Parkinson's disease (No. 22); and miscellaneous (No. 10)" 07/01/1981 - "Five patients with idiopathic orthostatic hypotension, two of whom had central nervous system manifestations (Shy-Drager syndrome), were treated with midodrine, an investigational alpha-adrenergic agonist, in a dosage of 2.5 to 5 mg three times daily" 11/01/1992 - "In order to increase CO and VR, we orally administered both denopamine 10 mg (a selective beta 1-adrenergic agonist) and midodrine HCl 4 mg (a selective alpha 1-adrenergic agonist) to six patients with progressive autonomic failure (AF)" Order ALL the reference details at left...
3.	Trimethaphan (Trimetaphan)IBA 05/01/2002 - "In patients with multiple system atrophy (Shy-Drager syndrome), supine hypertension is explained by residual sympathetic tone because it can be eliminated with the ganglionic blocker trimethaphan" Order ALL the reference details at left...
4.	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/01/1998 - "We conclude that ambulatory noradrenaline infusion is a new valuable tool for long-term treatment of advanced Shy-Drager syndrome." 01/01/1998 - "Ambulatory infusion of noradrenaline for long-term treatment of Shy-Drager syndrome." 03/01/1995 - "The Schellong test revealed deficient sympathetic orthostatic pressure response without an increase of plasma norepinephrine; therefore, a Shy-Drager syndrome was diagnosed" 02/01/1995 - "At this point, after an extensive survey of the literature, the diagnosis of Shy-Drager syndrome was proposed and proved by monitoring ECG and serum levels of noradrenaline during postural changes" 04/16/1985 - "Ambulatory noradrenaline infusion in refractory Shy-Drager syndrome]" Order ALL the reference details at left...
5.	Dopamine (Intropin)FDA LinkGeneric 05/01/1993 - "We report the case of an elderly woman with severe dysautonomic orthostatic hypotension in whom a deficit in dopamine B hydroxylase has been established" 05/01/1993 - "Dopamine B hydroxylase deficiency responsible for severe dysautonomic orthostatic hypotension in an elderly patient." 04/01/1976 - "Subsensitivity to dopamine was observed in patients with Parkinson's disease, but supersensitivity in those with the Shy-Drager syndrome." 10/02/1989 - "In both patients with Shy-Drager syndrome, basal plasma concentrations of epinephrine and dopamine were low under resting conditions and could not be stimulated in the upright position" 04/01/1976 - "Studies of pulse rate and blood pressure responses to graded intravenous infusions of noradrenaline and dopamine were performed on five patients with Parkinson's disease, five with the Shy-Drager syndrome and seven healthy subject" Order ALL the reference details at left...
6.	SASIBA 02/01/1978 - "Autopsy confirmed the Shy-Drager syndrome and multiple areas of degeneration were observed in areas of the CNS outside the medullary respiratory centers, suggesting their importance in the origin of the respiratory abnormalities in SAS." 02/01/1978 - "A patient with autonomic insufficiency and extrapyramidal signs (Shy-Drager syndrome) and sleep apnea syndrome (SAS) underwent hemodynamic studies" 03/01/2004 - "Although SAS is frequently associated with Shy-Drager syndrome but not with PAF, patients with PAF had been reported to have degenerative changes in the central nervous system overlapping with Shy-Drager syndrome or Lewy body disease" Order ALL the reference details at left...
7.	Dopamine Agonists (Dopamine Agonist)IBA 04/01/1981 - "In a controlled trial lisuride, an ergolene derivative with dopamine receptor agonist properties was given maximum tolerated doses (2.4 mg/day) to seven patients with multiple system atrophy with autonomic failure (Shy-Drager syndrome)" Order ALL the reference details at left...
8.	XenonIBA 01/01/1979 - "The experimental study of the autoregulation of cerebral blood flow (CBF), of the cerebrovascular reactivity and of their interaction is performed in a confirmed case of Shy-Drager syndrome, by means of the xenon-clearance technique" Order ALL the reference details at left...
9.	GABA-A Receptors (GABA(A) Receptor)IBA 08/01/1995 - "We used positron emission tomography with [11C]flumazenil to study gamma-aminobutyric acid type A/benzodiazepine receptor binding quantitatively in the cerebral hemispheres, basal ganglia, thalamus, cerebellum, and brainstem of 72 subjects, including 14 with multiple system atrophy of the ataxic (olivopontocerebellar atrophy) type, 5 with multiple system atrophy of the extrapyramidal/autonomic (Shy-Drager syndrome) type, 18 with sporadic olivopontocerebellar atrophy, 15 with dominantly inherited olivopontocerebellar atrophy, and 20 normal control subjects with similar age and sex distributions" Order ALL the reference details at left...
10.	LisurideIBA 04/01/1981 - "The use of lisuride in the treatment of multiple system atrophy with autonomic failure (Shy-Drager syndrome)." 04/01/1981 - "In a controlled trial lisuride, an ergolene derivative with dopamine receptor agonist properties was given maximum tolerated doses (2.4 mg/day) to seven patients with multiple system atrophy with autonomic failure (Shy-Drager syndrome)" Order ALL the reference details at left...

Therapies and Procedures

1.	Anesthesia 01/01/2001 - "Anesthesia for emergency surgery in a patient with Shy-Drager syndrome]" 10/01/1992 - "Anesthesia in Shy-Drager syndrome." 08/01/1979 - "Shy-Drager syndrome and anesthesia]" 06/01/1989 - "Anesthesia for Shy-Drager syndrome; effects of elastic bandage, phenylephrine, and IPPV]" Order ALL the reference details at left...
2.	Denervation 09/01/1988 - "In patients with progressive autonomic failure and multiple system atrophy, the bladder neck was incompetent in every case and the striated muscle of the urethra was affected by a process of denervation and re-innervation" 04/01/1987 - "These findings do not permit the vocal cord paralysis seen in the Shy-Drager syndrome to be explained by motorneuron loss and denervation" 01/01/1981 - "1. Denervation supersensitivity to adrenergic agonists occurs after degeneration of the sympathetic nervous system in the disease called multiple system atrophy (MSA) or the Shy Drager Syndrome.2. Supersensitivity to the chronotropic effect of i.v. isoprenaline on the heart was demonstrated in eight subjects with sympathetic nervous system degeneration and MSA.3. There was an increased number of beta-receptors present in MSA as measured by [H(3)]dihydroalprenolol ([H(3)]DHA) binding to beta-receptors on lymphocytes isolated from venous blood taken from the MSA subjects compared with [H(3)]DHA binding to lymphocytes from seven normal subjects" Order ALL the reference details at left...
3.	General Anesthesia 01/01/2001 - "A 53-year-old man with Shy-Drager syndrome underwent emergency surgery for the resection of the larynx under general anesthesia" 06/01/1989 - "A 57-year-old man with Shy-Drager syndrome underwent plastic surgery for decubitus on the buttocks under general anesthesia" 07/01/2005 - "A 61-year-old man with Shy-Drager Syndrome underwent partial pulmonary lobectomy under general anesthesia combined with thoracic epidural anesthesia" 07/01/2005 - "A patient with Shy-Drager syndrome managed under general anesthesia with thoracic epidural anesthesia]" Order ALL the reference details at left...
4.	Sympathectomy (Sympathectomies) 01/01/1997 - "Sympathetic denervation of myocardium demonstrated by 123I-MIBG scintigraphy in pure progressive autonomic failure." 10/01/1995 - "2. Eighteen subjects with chronic sympathetic denervation were studied; 12 had pure autonomic failure and six had additional neurological features of the Shy-Drager syndrome" Order ALL the reference details at left...
5.	Transplants (Transplant) 01/21/1984 - "A subgroup of patients with sleep apnoea and impairment of autonomic nervous control of the heart (heart transplants, autonomic neuropathy, Shy-Drager syndrome) did not show the cyclical heart rate pattern" Order ALL the reference details at left...