|1.||Wounds and Injuries (Trauma)
|4.||Multiple Organ Failure (MODS)
|1.||Huang, Zong-hai: 7 articles (09/2006 - 01/2003)|
|2.||Moore, Frederick A: 6 articles (10/2014 - 12/2002)|
|3.||Ward, Kevin R: 6 articles (07/2011 - 12/2006)|
|4.||Bahrami, Soheyl: 5 articles (01/2012 - 09/2003)|
|5.||Sun, Ying-gang: 5 articles (01/2004 - 01/2003)|
|6.||Redl, Heinz: 4 articles (11/2011 - 09/2003)|
|7.||White, Nathan J: 4 articles (07/2011 - 01/2010)|
|8.||McKinley, Bruce A: 4 articles (11/2009 - 12/2002)|
|9.||Kozhevnikova, L M: 4 articles (05/2009 - 05/2006)|
|10.||Avdonin, P V: 4 articles (05/2009 - 05/2006)|
|1.||Platelet Activating FactorIBA
01/01/1988 - "Protective effects of a platelet activating factor (PAF) antagonist and its combined treatment with prostaglandin (PG) E1 in traumatic shock."
11/01/1988 - "The purpose of this study was to determine if platelet-activating factor (PAF) is formed in the peritoneal fluid of rats following traumatic shock. "
11/01/1988 - "These findings are consistent with the formation of PAF in traumatic shock, and along with previous data of PAF antagonists ameliorating traumatic shock, support a role of platelet-activating factor in the pathogenesis of traumatic shock."
11/01/1988 - "Detection of platelet-activating factor during traumatic shock."
02/01/1998 - "Unexpected action of platelet activating factor antagonism after fluid resuscitation from traumatic shock."
|2.||Aprotinin (Trasylol)FDA Link
10/01/1979 - "Protective actions of aprotinin in acute traumatic shock."
05/01/1978 - "[Effect of combined use of aprotinin and corticosteroid in traumatic shock rats (author's transl)]."
10/01/1985 - "Aprotinin at a dose of 50,000 U/kg improved only endotoxin shock and showed a moderate but not significant effect on burn and traumatic shock. "
10/01/1979 - "Aprotinin has a beneficial effect on traumatic shock in rats possibly by its potent inhibitory action on MDF formation."
10/01/1979 - "The effect of the protease inhibitor, aprotinin, was examined in rats during traumatic shock. "
|3.||Alprostadil (Muse)FDA LinkGeneric
08/01/1987 - "PGE1 (1.2 micrograms/kg X min) significantly improved survival time during traumatic shock (191 +/- 29 vs. 108 +/- 19 min), drug vs. vehicle, respectively (p less than .03). "
01/01/1988 - "Moreover, combination therapy using a PAF antagonist and PGE1 may be useful for the treatment of traumatic shock."
08/01/1987 - "The effects of prostaglandin E1 (PGE1) were studied in a standardized model of traumatic shock in rats. "
08/01/1987 - "Beneficial effects of prostaglandin E1 infusion in experimental traumatic shock."
08/01/1987 - "In addition, PGE1 significantly attenuated plasma MDF activity during traumatic shock (58 +/- 10 vs. 27 +/- 7 U/ml), vehicle vs. drug, respectively (p less than .02). "
|4.||WEB 2086 (apafant)IBA
05/01/1997 - "In the absence of traumatic shock, WEB-2086 was associated with reduced mortality (four of five WEB-2086 treated pigs versus two of five vehicle pigs survived 5 hours; p = 0.07) and improved arterial PO2 (p = 0.05) and base excess (p = 0.04) 60 minutes after LPS administration. "
05/01/1997 - "LPS was then administered without an earlier episode of traumatic shock to animals treated with WEB-2086 or vehicle. "
02/01/1989 - "Protective effects of a specific platelet activating factor (PAF) antagonist, WEB 2086, in traumatic shock."
02/01/1989 - "We have investigated the role of platelet activating factor (PAF) in the pathogenesis of a murine model of traumatic shock using WEB 2086, a specific antagonist of PAF. "
01/01/2009 - "A package of medical measures that promote improved oxygen and acid-base balance in children with traumatic shock is stated."
04/01/2005 - "Our recent experimental study showed that peripheral muscle tissue oxygen saturation (StO2), determined noninvasively by near-infrared spectroscopy (NIRS), was more reliable than systemic hemodynamics or invasive oxygenation variables as an index of traumatic shock. "
07/01/2011 - "Traumatic shock can result in oxygen debt (O(2)D) accumulation that is fatal. "
01/01/2010 - "We hypothesize that oxygen transport measurements will be associated with clot strength during traumatic shock, and test this hypothesis using a swine model of controlled traumatic shock. "
01/01/2009 - "The time course of changes in oxygen and acid-base homeostatic parameters was studied in children with grades 1, 2, 3, and 4 traumatic shock. "
|6.||Sodium Chloride (Saline Solution)FDA LinkGeneric
06/01/1980 - "[Therapeutic effect of saline solution infusions in the late period of traumatic shock (an experimental study)]."
01/01/2009 - "The authors have studied influence of infusion of 800 ml RHEOSORBILACTUM, 500 ml VENOFUNDIN and 800 ml of 0,9% isotonic solution of sodium chloride with speed of 50-55 ml/mines on hemostasis, the maintenance of a liquid in the thorax, hemodynamic parameters in 60 patients with traumatic shock. "
03/01/1987 - "[Therapeutic effect of a hypertonic solution of sodium chloride in experimental traumatic shock]."
10/01/1990 - "Analysis of potential risks associated with 7.5% sodium chloride resuscitation of traumatic shock."
02/01/1996 - "Hypertonic sodium chloride/dextran solution is safe and effective for resuscitating dogs in traumatic shock. "
|7.||Dextrans (Dextran)FDA Link
01/01/1989 - "Perspectives on clinical trials for hypertonic saline/dextran solutions for the treatment of traumatic shock."
04/01/1986 - "[Comparative evaluation of the effectiveness of the action of dextran preparations in the combined therapy of traumatic shock]."
05/01/1968 - "[On the therapeutic effectiveness of the solution of dry polyglucin in traumatic shock and acute blood loss]."
10/01/2001 - "Infusions of hyperosmotic-hyperoncotic solutions such as hypertonic saline dextran (HSD) are used in Europe for resuscitation of traumatic shock and perioperative volume support as an adjunct to conventional isotonic crystalloids. "
10/01/1965 - "[The use of polyglucin in the treatment of traumatic shock by a specialized first aid team]."
07/01/1962 - "[Alkaline and acid phosphatase activity of the liver during experimental traumatic shock (histochemical study)]."
07/01/1970 - "[Acid phosphatase activity in rat liver and kidney tissue in experimental traumatic shock]."
01/01/1969 - "[Acid phosphatase activity of liver cells as an index of activity of the reticuloendothelial system during traumatic shock in rabbits]."
05/01/1965 - "[Acid phosphatase (phosphomonoesterase II) activity in the brain of rats under traumatic shock]."
10/01/1962 - "Similarly, circulating levels of acid phosphatase and beta glucuronidase were increased during traumatic shock in rats and rabbits, and during endotoxin shock in rats. "
01/01/1985 - "Protective effects of a new LTD4 antagonist (LY-171883) in traumatic shock."
01/01/1985 - "The beneficial effect of LTD4 antagonism in the present study is consistent with the concept that peptide leukotrienes are important mediators of the pathogenesis of traumatic shock."
01/01/1985 - "We studied the effects of a selective antagonist of LTD4 (LY-171883, 2 and 4 mg/kg) in traumatic shock. "
10/01/1984 - "The increased survival time and reduced MDF activity afforded by these inhibitors suggest a significant role for lipoxygenase metabolites, particularly LTC4 and LTD4, in the pathogenesis of traumatic shock."
|10.||Insulin (Novolin)FDA Link
04/01/2011 - "The results suggest early treatment with intensive insulin therapy is effective for traumatic shock combined with MODS and can decrease the length of hospital stay and the mortality."
04/01/2011 - "The therapeutic effects of intensive insulin therapy in treatment of traumatic shock combined with multiple organ dysfunction syndrome (MODS) were investigated. "
04/01/2011 - "Clinical effects of intensive insulin therapy treating traumatic shock combined with multiple organ dysfunction syndrome."
01/01/1979 - "Since alterations in insulin responsiveness, especially insulin resistance, have been related to the metabolic sequelae of shock, the present study evaluated insulin responsiveness in traumatic shock. "
04/01/2011 - "A total of 114 patients with traumatic shock combined with MODS were randomly divided into two groups: control group (n=56) treated with conventional therapy, and intensive insulin therapy group (n=58) treated with conventional therapy plus continuous insulin pumping to control the blood glucose level at range of 4.4-6.1 mmol/L. "
07/01/2000 - "It is associated with improved base deficit clearance and a lower rate of organ dysfunction after resuscitation from traumatic shock."
03/01/1991 - "This work underscores the importance of prolonged periods of study when evaluating brain resuscitation from traumatic shock."
11/01/2015 - "We examined H2S as a pharmacologic adjunct to resuscitation in a porcine model of severe traumatic shock. "
07/01/2015 - "Impaired hemostasis frequently occurs after traumatic shock and resuscitation. "
01/01/2015 - "The recognition of the association between the development of ACS and resuscitation urged the need for new approach in traumatic shock management. "
|2.||Intensive Care (Surgical Intensive Care)
01/01/1995 - "Use of ASO in a complex of intensive care measures for the treatment of traumatic shock at the prehospital stage is physiological and conducive to optimization of medical care rendered to victims at the early stages of treatment."
01/01/1995 - "The mechanisms of antihypotensive action of antishock overalls (ASO) were studied on the basis of comparison of 30 patients with traumatic shock at the prehospital stage of medical care; in 15 of these ASO was used, in the other 15 traditional antishock intensive care. "
01/01/1993 - "Surgical operations with the exception of urgent ones which form part of urgent intensive care must be postponed to the time when clinical manifestations of traumatic shock have completely subsided. "
05/01/1994 - "High efficacy of ASO use for stabilization of hemodynamic parameters in patients with severe trauma complicated with shock has been demonstrated and the advisability of its use in the complex of intensive care procedures in traumatic shock at prehospital stage has been proved."
05/01/1994 - "The efficacy of the early use of antishock overalls (ASO) as part of intensive care for traumatic shock is assessed in the clinical study performed in 15 patients with severe mechanical trauma complicated with shock. "
03/01/1989 - "The efficacy of hyperbaric oxygenation (HBO, 2 atm, 1 h, altitude chamber "Irtysh-MT") has been studied in acute experiments on 56 adult dogs with hemorrhagic and traumatic shock. "
11/01/1978 - "[Extracorporeal perfusion and hyperbaric oxygenation in the treatment of severe traumatic shock]."
09/01/1964 - "THE EFFECT OF HYPERBARIC OXYGENATION (OHP) ON THREE FORMS OF SHOCK--TRAUMATIC, HEMORRHAGIC, AND SEPTIC."
|4.||Positive-Pressure Respiration (PEEP)
09/01/1986 - "[O2 transport as a criterion of the efficacy of artificial pulmonary ventilation using positive end-expiratory pressure in traumatic shock patients]."
11/01/2011 - "In low perfusion states, such as cardiac arrest and traumatic shock, the rise in intrathoracic pressure that accompanies positive-pressure ventilation can significantly impede venous return and lead to a decrease in cardiac output. "