Traumatic Shock

01/01/2017 - "Background: Many strategies have been utilized to treat traumatic shock via improved oxygen delivery (DO2), while fewer have been used to in an attempt to reduce oxygen demand (VO2). "
01/01/2009 - "A package of medical measures that promote improved oxygen and acid-base balance in children with traumatic shock is stated."
01/01/2022 - "Imbalance in RP reflects systemic oxidative stress, and whole blood RP measures have been shown to correlate with oxygen debt level over time in swine traumatic shock. "
07/01/2011 - "Traumatic shock can result in oxygen debt (O(2)D) accumulation that is fatal. "
12/07/2010 - "We hypothesize that oxygen transport measurements will be associated with clot strength during traumatic shock, and test this hypothesis using a swine model of controlled traumatic shock. "

04/01/1976 - "[Field study on the therapeutic value of trasylol in traumatic shock]."
01/01/1976 - "[Results of a field study on the therapeutic value of aprotinin in traumatic shock (author's transl)]."
10/01/1979 - "Protective actions of aprotinin in acute traumatic shock."
04/01/1976 - "A report of the results of a multicenter study including 4686 patients concerning the therapeutic value of Trasylol (Aprotinin) in traumatic shock. "
04/01/1976 - "The importance of a time factor in shock treatment and the effects of Trasylol in traumatic shock are emphasized."

11/01/1988 - "The purpose of this study was to determine if platelet-activating factor (PAF) is formed in the peritoneal fluid of rats following traumatic shock. "
11/01/1988 - "These findings are consistent with the formation of PAF in traumatic shock, and along with previous data of PAF antagonists ameliorating traumatic shock, support a role of platelet-activating factor in the pathogenesis of traumatic shock."
11/01/1988 - "Detection of platelet-activating factor during traumatic shock."
02/01/1998 - "Unexpected action of platelet activating factor antagonism after fluid resuscitation from traumatic shock."
05/01/1997 - "Unexpected action of platelet activating factor antagonism after fluid resuscitation from traumatic shock."

09/01/1979 - "Protective effects of a novel thromboxane analog in lethal traumatic shock."
01/01/1980 - "Beneficial actions of a new thromboxane analog in traumatic shock."
01/01/1989 - "Protective effects of a combination thromboxane synthesis inhibitor-receptor antagonist, R-68070, during murine traumatic shock."
02/01/1990 - "These results indicate that PDT-induced lethality is consistent with a traumatic shock syndrome and suggest that endogenous vasoactive mediators of shock such as prostaglandins, thromboxanes, and histamine are associated with the lethality induced by localized PDT in mice."

08/01/1987 - "PGE1 (1.2 micrograms/kg X min) significantly improved survival time during traumatic shock (191 +/- 29 vs. 108 +/- 19 min), drug vs. vehicle, respectively (p less than .03). "
08/01/1987 - "The effects of prostaglandin E1 (PGE1) were studied in a standardized model of traumatic shock in rats. "
08/01/1987 - "Beneficial effects of prostaglandin E1 infusion in experimental traumatic shock."
01/01/1988 - "Moreover, combination therapy using a PAF antagonist and PGE1 may be useful for the treatment of traumatic shock."
08/01/1987 - "In addition, PGE1 significantly attenuated plasma MDF activity during traumatic shock (58 +/- 10 vs. 27 +/- 7 U/ml), vehicle vs. drug, respectively (p less than .02). "

05/01/1997 - "In the absence of traumatic shock, WEB-2086 was associated with reduced mortality (four of five WEB-2086 treated pigs versus two of five vehicle pigs survived 5 hours; p = 0.07) and improved arterial PO2 (p = 0.05) and base excess (p = 0.04) 60 minutes after LPS administration. "
05/01/1997 - "LPS was then administered without an earlier episode of traumatic shock to animals treated with WEB-2086 or vehicle. "
02/01/1989 - "Protective effects of a specific platelet activating factor (PAF) antagonist, WEB 2086, in traumatic shock."
02/01/1989 - "We have investigated the role of platelet activating factor (PAF) in the pathogenesis of a murine model of traumatic shock using WEB 2086, a specific antagonist of PAF. "

01/01/1989 - "Perspectives on clinical trials for hypertonic saline/dextran solutions for the treatment of traumatic shock."
10/01/2001 - "Infusions of hyperosmotic-hyperoncotic solutions such as hypertonic saline dextran (HSD) are used in Europe for resuscitation of traumatic shock and perioperative volume support as an adjunct to conventional isotonic crystalloids. "
04/01/1986 - "[Comparative evaluation of the effectiveness of the action of dextran preparations in the combined therapy of traumatic shock]."
10/01/1965 - "[The use of polyglucin in the treatment of traumatic shock by a specialized first aid team]."
05/01/1968 - "[On the therapeutic effectiveness of the solution of dry polyglucin in traumatic shock and acute blood loss]."

07/01/1962 - "[Alkaline and acid phosphatase activity of the liver during experimental traumatic shock (histochemical study)]."
07/01/1970 - "[Acid phosphatase activity in rat liver and kidney tissue in experimental traumatic shock]."
01/01/1969 - "[Acid phosphatase activity of liver cells as an index of activity of the reticuloendothelial system during traumatic shock in rabbits]."
05/01/1965 - "[Acid phosphatase (phosphomonoesterase II) activity in the brain of rats under traumatic shock]."
10/01/1962 - "Similarly, circulating levels of acid phosphatase and beta glucuronidase were increased during traumatic shock in rats and rabbits, and during endotoxin shock in rats. "

01/01/2022 - "Traumatic shock was constructed in rats as experimental model, and liquid resuscitation was performed using HES and lactated Ringer's (LR). "
01/01/2019 - "To produce traumatic shock, the rats were subjected to bilateral femoral traumatic fracture and blood withdrawal from the femoral artery to decrease mean arterial pressure (MAP) to 35 mm Hg. Hypovolemic status (at a MAP of 35 to 40 mm Hg) was sustained for 1 hour followed by fluid resuscitation with shed blood and 20 mL/kg of lactated Ringer's solution. "
09/01/1999 - "Twenty-eight male baboons (Papio ursinus), 18 to 29 kg. Hemorrhagic-traumatic shock was created by complement activation with cobra venom factor, followed by withdrawal of blood to a mean arterial pressure of 35 to 45 mm Hg. Blood and lactated Ringer's solution were reinfused. "
01/01/2004 - "In series I, 36 rats were equally divided into six groups: sham-operated, untreated (traumatic shock without fluid infusion), and with lactated Ringer's resuscitation (LR) of 1.0, 1.5, 2.0 or 3.0 times the shed blood (1, 1.5, 2, 3 vol LR group). "
02/01/1989 - "Permeability studies in a hypovolemic traumatic shock model: comparison of Ringer's lactate and albumin as volume replacement fluids."

09/01/2003 - "Plasma D-lactate may be a useful marker of intestinal injury after hemorrhagic/traumatic shock."
09/01/2003 - "Our data suggest that hemorrhagic/traumatic shock is associated with mucosal damage and increased plasma D-lactate levels. "
09/01/2003 - "Increased plasma D-lactate is associated with the severity of hemorrhagic/traumatic shock in rats."
09/01/2003 - "Plasma D-lactate levels were already significantly increased at the end of severe hemorrhagic/traumatic shock and remained high during inadequate resuscitation. "
09/01/2003 - "The present study was designed to determine the kinetics of circulating D-lactate levels and to examine whether the severity of shock affects circulating D-lactate levels in rats subjected to hemorrhagic/traumatic shock. "

07/01/2000 - "It is associated with improved base deficit clearance and a lower rate of organ dysfunction after resuscitation from traumatic shock."
01/01/2022 - "A large number of studies have shown that effective volumetry resuscitation on the basis of controlled injury can not only increase the success rate of early resuscitation but also reduce systemic inflammatory response and improve the cure rate of severe traumatic shock. "
01/01/2019 - "The aim of the present study was to investigate the dynamic change of BBB changes during traumatic shock and resuscitation as well as the mechanisms involved. "
02/01/2018 - "The present study aimed to assess whether different fluid resuscitation strategies had an influence on aged patients with traumatic shock.A total of 219 patients with traumatic shock were recruited retrospectively. "
10/01/2015 - "The aim of this study is to investigate the effect of different resuscitation fluid compositions on the emergency resuscitation for patients with traumatic shock. "

10/01/1953 - "Experimental studies on the use of large volumes of saline in the therapy of traumatic shock."
01/01/2013 - "Treatment is primarily supportive; however, research into novel therapeutics for traumatic shock is ongoing and promises some direction for future care."
12/01/2011 - "The purpose of this report is to review the most important advances in traumatic shock therapy in the last five years. "
06/01/2009 - "The patients were divided into two groups: patients with traumatic shock based on standard program of intensive therapy and patients with traumatic shock based on standard program of intensive therapy plus Plaferone LB. "
01/01/2009 - "[Application of Rheosorbilactum in the therapy of traumatic shock: comparative study]."

12/01/2017 - "Efficacy of Uncross-Matched Type O Packed Red Blood Cell Transfusion to Traumatic Shock Patients: a Propensity Score Match Study."

03/01/1955 - "[Further therapeutic utilization of intravenous administration of novocaine in experimental traumatic shock]."
04/01/1953 - "[Intravenous administration of novocain as a preventive measure in traumatic shock]."
01/01/1990 - "In acute experiment on 86 adult rabbits with traumatic shock modelled according to Cannon, it was established that intravenous administration of Nalorphine at the doses of 0.5 and 2 mg/kg of weight at the early period of shock contributed to prolongation of lifetime of the majority of animals. "
09/01/1973 - "[Moderate cranio-cerebral hypothermia and intravenous administration of novocaine in traumatic shock]."
11/01/2005 - "Meanwhile, intravenous administration of delta and kappa opioid receptor antagonists ICI174,864 and Nor-BNI also significantly increased the mean arterial blood pressure, improved the hemodynamic parameters, and prolonged the survival rate of traumatic shock rats. "

01/01/1995 - "Use of ASO in a complex of intensive care measures for the treatment of traumatic shock at the prehospital stage is physiological and conducive to optimization of medical care rendered to victims at the early stages of treatment."
01/01/1995 - "The mechanisms of antihypotensive action of antishock overalls (ASO) were studied on the basis of comparison of 30 patients with traumatic shock at the prehospital stage of medical care; in 15 of these ASO was used, in the other 15 traditional antishock intensive care. "
01/01/1993 - "Surgical operations with the exception of urgent ones which form part of urgent intensive care must be postponed to the time when clinical manifestations of traumatic shock have completely subsided. "
01/01/2009 - "Battlefield trauma, traumatic shock and consequences: war-related advances in critical care."
05/01/1994 - "High efficacy of ASO use for stabilization of hemodynamic parameters in patients with severe trauma complicated with shock has been demonstrated and the advisability of its use in the complex of intensive care procedures in traumatic shock at prehospital stage has been proved."