|5.||Wounds and Injuries (Trauma)
|1.||Deitch, Edwin A: 66 articles (12/2014 - 05/2002)|
|2.||Cuzzocrea, Salvatore: 56 articles (06/2012 - 03/2002)|
|3.||Lingeman, James E: 42 articles (01/2016 - 01/2002)|
|4.||Alam, Hasan B: 39 articles (12/2015 - 08/2002)|
|5.||Lu, Qi: 36 articles (07/2012 - 01/2002)|
|6.||Li, Tao: 35 articles (12/2015 - 11/2005)|
|7.||Xu, Da-Zhong: 35 articles (12/2011 - 06/2002)|
|8.||Moore, Ernest E: 34 articles (12/2015 - 07/2002)|
|9.||Radermacher, Peter: 34 articles (12/2015 - 01/2003)|
|10.||Nakai, Akira: 34 articles (01/2015 - 08/2002)|
04/01/2015 - "Among the four concentrations of AVP, 5 × 10 U/mL had the best effect: it significantly improved hemodynamics and increased cardiac function, oxygen delivery, as well as hepatic blood flow and hepatic function in the shock rats. "
09/01/2004 - "Thus, the oxygen-carrying macromolecues are extremely effective in the treatment of shock patients. "
06/01/2005 - "There is also evidence that central venous oxygen saturation measurement is beneficial in other types of shock. "
06/01/2003 - "The presence of 0.9 g/dL of high oxygen affinity MalPEG-Hb improves microvascular blood flow and oxygen transport during shock to a significantly greater extent than that attainable with blood or HES."
01/12/2009 - "Study group patients with postresuscitation shock vs corresponding controls had improved survival to hospital discharge (8 of 27 patients [30%] vs 0 of 15 [0%]; P = .02), improved hemodynamics and central venous oxygen saturation, and more organ failure-free days. "
09/01/2012 - "The major hemodynamic difference between the two groups was a significant reduction in heart rate in the patients treated with vasopressin (P <.0001), and this was most pronounced in the less severe shock stratum (treatment × shock stratum interaction, P =.03). "
01/01/2008 - "The use of vasopressin is an alternative therapy for vasodilatory shock with better outcome. "
04/01/2008 - "Any therapeutic efficacy of infusion of vasopressin for post-cardiotomy shock in children is likely due to reasons other than physiologic replacement."
08/01/2007 - "Examples of types of shock resistant to catecholamine pressors in which exogenous vasopressin was effective in restoring arterial pressure continued to accumulate. "
06/01/2000 - "Vasopressin effective in reversing catecholamine-resistant vasodilatory shock."
|3.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/15/2015 - "The present study was designed to evaluate the protective effects of Ag-nps and heat shock treatment on tumor necrosis factor-α (TNF-α)-induced cell damage in Clone 9 cells. "
11/15/2005 - "Anti-TNF-alpha pretreatment was protective against shock whereas anti-IFN gamma pretreatment and delayed anti-TNF-alpha treatment were not. "
04/01/1994 - "The data presented in this report strongly suggest that LZM-LPS complex formation completely abrogates tumor necrosis factor production and the mortality caused by LPS and that LZM may be useful for the treatment of endotoxin shock."
03/01/2000 - "TNF-alpha neutralization improved cardiac function by 50% in the combined shock and clamp rats. "
06/30/1999 - "The increase in myocardial TNF-alpha was blunted by prior heat shock and the reduced myocardial TNF-alpha level was correlated with improved cardiac functional recovery. "
|4.||Adenosine Triphosphate (ATP)IBA
10/01/1993 - "3. Comparison of the concentrations of high-energy phosphate metabolites before and after electric shock using 31P-NMR revealed a marked decrease in beta-ATP and an increase in that of Pi. "
06/01/2000 - "Heat-shock preconditioning significantly improved the survival rate, suppressed the increase in liver-related enzyme levels and maintained adenosine triphosphate levels (P<0.01 each). "
01/01/1996 - "Administration of Lip-ATP significantly improved hepatic blood flow during shock (13.2 +/- 1.7 ml/min/100 g tissue in the Lip-ATP group vs. 9.4 +/- 2.2, in the control group, and 8.9 +/- 2.9 in the free ATP group) and during reperfusion (20.9 +/- 2.3, 16.3 +/- 2.2, and 16.2 +/- 1.8 ml/min/100 g tissue, respectively). "
09/01/1977 - "It has been shown that infusion of ATP-MgCl2 proved beneficial in the treatment of shock; however, it is not known whether this effect is due to improvement in the microcirculation or direct provision of energy or a combination of the above or other effects. "
09/01/2008 - "Before discharge from the hospital each patient had an electrophysiological study (EPS) performed through the device, to assess the efficacy of ATP and low-joule shock at terminating VFVT. "
|5.||Naloxone (Narcan)FDA LinkGeneric
06/01/2002 - "Pretreatment with naloxone before HS attenuated the protective effects in a dose-dependent fashion, with significant attenuation of protection occurring at 15 mg/kg naloxone versus heat shock (42 +/- 6 vs. 16 +/- 3%, P < 0.001). "
11/01/1988 - "Naloxone treatment improved blood pressure significantly during endotoxin shock, as would be expected with the observed increase in total peripheral vascular resistance and no significant change in cardiac output. "
08/01/1980 - "In endotoxin shock in rats, naloxone's effects were stereospecific and were observed with intravenous (iv) doses as low as 0.1 mg/kg. In endotoxin shock in dogs, naloxone treatment significantly improved both cardiovascular parameters and survival. "
01/01/2003 - "Many case reports have suggested that naloxone (an opiate antagonist) might be an effective treatment for shock in humans, but others have not supported such a point of view. "
10/01/1989 - "Naloxone and shed blood were equally effective in improving hepatic and renal blood flow; gastric, intestinal, pancreatic, and splenic blood flow remained unchanged from shock values in both groups. "
|6.||Epinephrine (Adrenaline)FDA LinkGeneric
01/01/1981 - "There was significantly greater regional flow to spleen, gastrointestinal tract, and pancreas during shock in the epinephrine-tolerant group."
02/01/1966 - "[Experimental studies on the shock induced by the injection of epinephrine into the palate and the prevention against it]."
04/01/2015 - "He was afterwards treated with an epinephrine drip for distributive shock. "
09/01/2013 - "Similarly, all 15 children in cold shock were initially commenced on adrenaline. "
07/01/2011 - "On transfer to the hospital, she developed shock refractory to multiple vasopressors, which responded to continuous infusions of epinephrine. "
|7.||Dopamine (Intropin)FDA LinkGeneric
10/26/2007 - "Exposure to mild foot shock stimulated basal dopamine efflux in saline-treated groups only, although the effect was significantly greater in isolation-reared rats. "
09/01/1993 - "Dopamine is widely used for the treatment of cardiogenic and hypovolemic shock. "
08/01/2002 - "To investigate the protective effects of small dose of dopamine on the intestinal mucosa of scalded rats in shock stage. "
08/01/2002 - "[The protective effects of small dose of dopamine on the intestinal mucosa of scalded rats in shock stage]."
08/01/1985 - "Dopamine improved the circulation in seven animals; one animal died in refractory shock during dopamine infusion. "
|8.||Proteins (Proteins, Gene)IBA
07/01/2012 - "High level expression of YnaI, YbiO or YjeP proteins from a multicopy plasmid in the Δ7 strain (MJFGH) leads to substantial protection against hypoosmotic shock. "
02/01/2010 - "Heat shock is a well-known stress response characterized by a rapid synthesis of a set of proteins which are responsible for protection against stress. "
10/01/2004 - "This then initiates the transcription of a series of heat shock genes (hsp genes) that encode chaperone proteins protective against heat stress. "
06/01/2010 - "These results suggest that transient heat shock lessens Abeta toxicity by diminishing Abeta oligomerization, which provides a link between up regulation of endogenous chaperone proteins and protection against Abeta proteotoxicity in vivo."
08/01/2009 - "Hence, our findings demonstrate that NFkappaB-induced autophagy during heat shock recovery is an additional cell response to HS-induced protein denaturation/aggregation; this mechanism increases cell survival, probably through clearance of irreversibly damaged proteins."
|9.||Heat-Shock Proteins (Heat-Shock Protein)IBA
07/01/1989 - "The clone has a length of 1.1 kb and codes for the complete heat-shock protein which was reported to be associated with the grana region of the thylakoid membranes and ascribes protection against photoinhibition during heat-shock. "
05/01/2004 - "This screening yielded three promoters of genes belonging to the heat shock regulon (dnaK, lon, clpPX), suggesting a role for heat shock proteins in protection against, and/or repair of, damage caused by high pressure. "
02/01/2005 - "Indeed, there is experimental evidence that overexpression of specific heat shock proteins or heat shock factors produce protective effects similar to those observed after stress preconditioning. "
12/01/1995 - "Recent studies have shown that improved myocardial salvage after heat-shock pretreatment correlates with the amount of induced cardiac heat-shock protein (HSP)72. "
06/01/2010 - "Expression of heat shock factors and subsequent heat shock protein plays a role in protection against proteotoxicity in invertebrate and vertebrate models. "
11/01/2007 - "However, the plants exposed to dark treatment plus heat shock showed a significant reduction in the CO(2) assimilation rate and also in the values of V(cmax) and J(max). "
03/01/2012 - "The poor yield of soluble recombinant protein was improved by various strategies including cold shock expression, chaperone co-expression, and employment of mutant E. "
07/01/2007 - "The SIN-1-induced improvement in the P(CO(2)) gap was accompanied by an increase in serosal muP(O(2)) above shock levels. "
07/15/2006 - "Pretreatment with a carbon monoxide donor improved PDR(ICG) (DCM/Shock: 18 +/- 3.19%/min, p = 0.022) compared with Vehicle/Shock. "
06/01/1997 - "DOB (2.5 to 10.0 micrograms/kg/min) with and without shock improved CO, LV dP/dt, SVR and SvO2. "
|1.||Lithotripsy (Extracorporeal Shockwave Lithotripsy)
03/01/2015 - "Extracorporeal shock wave lithotripsy is a highly effective and safe treatment of stones of a solitary kidney. "
01/01/2012 - "The best treatment modalities for large proximal ureteral stones are controversial, and include extracorporeal shock wave lithotripsy, ureterolithotripsy, percutaneous nephrolithotripsy, laparoscopic ureterolithotomy and open surgery. "
03/01/2011 - "When stone removal is indicated SWL (Shock Wave Lithotripsy) and ureteroscopy (URS) are the two most commonly offered interventional procedures and they are both acceptable as first-line treatment. "
06/01/2005 - "Since 1980, extra corporeal shock wave lithotripsy (ESWL) has become the first line treatment for most stones in adults and children. "
10/01/2001 - "Although ureteroscopy and shock wave lithotripsy are highly effective for treatment of distal ureteral stones, we believe that HM3 shock wave lithotripsy, albeit slightly more costly, is preferable to manipulation with ureteroscopy since it is equally efficacious, more efficient and less morbid."
04/01/2015 - "Hypotensive resuscitation in combination with AVP maintenance for 3 hours significantly reduced total blood loss and fluid requirement during hypotensive resuscitation period and significantly improved the survival of shock rats as compared with hypotensive resuscitation alone. "
01/01/2015 - "The shock index before resuscitation was similar in the two groups but improved significantly following resuscitation in the SAMM group (p 0.002). "
01/01/2006 - "Metabolic activity decreased during shock and improved with resuscitation, without any significant inter-group differences. "
06/01/2004 - "We sought to confirm this to be the mechanism by which high-volume saline administration (comparable to that used in resuscitation of shock) results in improved cardiac output in normal healthy volunteers. "
10/01/2001 - "In case of shock or compulsory delayed resuscitation, rapid fluid resuscitation during early postburn stage was beneficial with critical hemodynamic monitoring. "
|3.||Cardiopulmonary Resuscitation (CPR)
01/01/2014 - "In a multivariate regression model that included study site, age, bystander CPR, shock on admission, comorbid medical conditions, witnessed arrest, and time to return of spontaneous circulation, early CC was independently associated with a significant reduction in the risk of death (OR 0.35, 95% CI 0.18-0.70, p=0.003). "
04/01/2009 - "Despite the improved median frequency in the preshock cardiopulmonary resuscitation group, 24-hour survival with favorable neurological status was significantly worse in the preshock cardiopulmonary resuscitation group (1/13) compared with the shock-first group (8/13, P=0.01). "
07/01/2011 - "In our study, CPR prior to attempted defibrillation did not present a better outcome compared with shock first as measured by either one-month survival or neurologically favorable one-month survival, after adjusting for potential confounders. "
12/01/2000 - "Although effective in improving outcome of prolonged VF, CPR preceding countershock of VF of 5-minute duration does not improve the response to the first shock, decrease the incidence of postshock pulseless electrical activity, or the rate of return of circulation. "
04/07/1999 - "Studies in animals have shown improved outcomes when cardiopulmonary resuscitation (CPR) was administered prior to an initial shock for VF of several minutes' duration. "
03/01/2013 - "The development of new ICD leads, shock algorithms, high-energy defibrillators and rapid energy supply has improved the devices. "
05/01/1988 - "Low-energy (100 J) shocks given to high-impedance (greater than or equal to 70 omega) patients had a poor success rate; in such high-impedance patients significant improvement in shock success rate was achieved by the energy-adjusting defibrillators. "
12/01/2012 - "The novel defibrillator used in this study was able to consistently deliver shocks on the upslope portion of the VF wave but did not show an improvement in shock success."
08/01/2005 - "Studies have shown that despite shock discomfort, quality of life was improved in patients with atrial defibrillators and the need for repeated hospitalizations was reduced. "
10/01/2010 - "Device technology has impressively improved, but the principal concept remained the same: automatic shock delivery to a fibrillating heart by an implanted defibrillator will restore normal heart rhythm and save the life of the patient."
|5.||Electric Countershock (Cardioversion)
09/01/2001 - "Quadruple pads external cardioversion is highly effective in converting chronic AF refractory to standard shock protocols to sinus rhythm. "
01/01/1976 - "The efficacy of DC shock and the maintenance of sinus rhythm after cardioversion was greater in patients with AF having a slower rate and a longer MAP."
12/01/2005 - "A strategy of approximately 24-hour delay in cardioversion shock timing decreased the incidence of ERAF, relative to a shock delivered within a few hours of AF onset. "
03/01/2002 - "Reversal of shock polarity does not improve transthoracic cardioversion efficacy with a standard damped sinusoidal monophasic waveform. "
01/02/2007 - "The aim of this study was to compare such a protocol with a protocol involving a high initial energy shock, anteroposterior paddle position and reversal of shock polarity, on cardioversion efficacy, total energy delivery, use of sedation and patient tolerability. "