Sex Hormone-Binding Globulin

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927 relevant articles (12 outcomes, 106 trials/studies) found for this Bio-Agent

Description: A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Sex hormone-binding protein has the same amino acid sequence as ANDROGEN-BINDING PROTEIN. They differ by their sites of synthesis and post-translational oligosaccharide modifications.

Also Known As:

Binding Globulin, Testosterone-Estradiol; Globulin, Sex Hormone-Binding; Globulin, Testosterone-Estradiol Binding; Hormone-Binding Globulin, Sex; Sex Hormone Binding Globulin; Sex Steroid Binding Protein; Steroid-Binding Protein, Sex; Testosterone Estradiol Binding Globulin; Sex Steroid-Binding Protein; Testosterone-Estradiol Binding Globulin

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins

Proteins: 58433

Carrier Proteins: 7795

Sex Hormone-Binding Globulin: 927

Blood Proteins: 3862

Serum Globulins: 74

Beta-Globulins: 144

Sex Hormone-Binding Globulin: 927

Globulins: 305

Serum Globulins: 74

Beta-Globulins: 144

Sex Hormone-Binding Globulin: 927

Experts

1.	Catalano, M G: 4 articles (04/2006 - 02/2001)
2.	Fortunati, N: 4 articles (04/2006 - 02/2001)
3.	Sherman, Mark E: 3 articles (01/2007 - 07/2005)
4.	Frairia, R: 3 articles (01/2005 - 02/2001)
5.	Tsatsoulis, Agathocles: 2 articles (06/2008 - 12/2003)
6.	Georgiou, Ioannis: 2 articles (06/2008 - 12/2003)
7.	Xita, Nectaria: 2 articles (06/2008 - 12/2003)
8.	Cai, Hui: 2 articles (04/2007 - 05/2005)
9.	Zheng, Wei: 2 articles (04/2007 - 05/2005)
10.	Cai, Qiuyin: 2 articles (04/2007 - 05/2005)

Related Diseases

1.	Hirsutism 07/01/1992 - "This study was designed to investigate the most important factors affecting serum concentrations of sex hormone-binding globulin (SHBG) in women with hirsutism. " 01/01/2008 - "We investigated 252 non-obese female subjects aged 13-39 years to evaluate if an exaggerated descent of sex hormone binding globulin (SHBG) levels during adolescence can play a role in the development of hirsutism. " 01/01/2008 - "Sex hormone binding globulin decrease as a potential pathogenetic factor for hirsutism in adolescent girls." 02/01/2006 - "MAIN OUTCOME MEASURE(S): Hirsutism score, lipid, androgen, and sex hormone-binding globulin (SHBG) levels were evaluated at baseline. " 06/01/2002 - "This could be an advantage in cases with low plasma levels of sex hormone-binding globulin (SHBG) as low levels of SHBG may promote androgenic stigmata such as hirsutism and a lowering of the voice. " Order ALL the reference details at left...
2.	Weight Loss (Weight Reduction) 04/01/2002 - "Sex hormone-binding globulin levels and cardiovascular risk factors in morbidly obese subjects before and after weight reduction induced by diet or malabsorptive surgery." 12/01/1989 - "The significant rise in sex-hormone binding globulin was most probably associated with the weight reduction of 3.1 +/- 1.2 kg per week. " 01/01/1997 - "OBJECTIVE: To investigate the effects of weight loss on sex hormone-binding globulin (SHBG) in massively obese males and whether normal SHBG concentrations could be obtained regardless or not of the achievement of normal body weight values. " 01/01/2007 - "OBJECTIVE: The aim of this study was to assess the impact of insulin sensitivity on the relationship between sex hormone-binding globulin (SHBG) and insulin levels during active weight loss in euthyroid obese women. " 01/01/2007 - "Relationship between insulin and sex hormone-binding globulin levels during weight loss in obese women." Order ALL the reference details at left...
3.	Acne Vulgaris 01/01/2004 - "Hirsutism and acne severity correlated negatively with serum sex hormone-binding globulin (SHBG) levels (p<0.05). " 11/01/1993 - "RESULTS: Patients with acne and those with isolated hirsutism showed significantly decreased sex hormone binding globulin plasma levels. " 07/01/1981 - "Reduced circulating sex hormone binding globulin (SHBG) levels were found in 54% of a group of women with moderate to severe acne and in 60% of another group of twenty-three women who had acne complicated by hirsutism and/or irregular menstrual cycles. " 09/01/1989 - "Clinical evidence from several trials confirms that sex hormone-binding globulin levels are increased, plasma androgen levels are decreased, and acne is markedly improved with the use of Triphasil and Nordette, suggesting a non-androgenic profile." 01/01/1986 - "This study investigated pituitary function in male acne patients and serum levels of dehydroepiandrosterone sulphate (DHEA-S), sex hormone binding globulin (SHBG), and other biochemical parameters in male acne patients and in female acne patients before and after oral contraceptive (OC) treatment. " Order ALL the reference details at left...
4.	Insulin Resistance 09/17/2009 - "BACKGROUND: Circulating sex hormone-binding globulin levels are inversely associated with insulin resistance, but whether these levels can predict the risk of developing type 2 diabetes is uncertain. " 02/01/2009 - "It was significantly correlated with numerous risk factors, above all body mass index and waist girth (r > or = 0.6), homeostatic model-assessed insulin resistance, blood pressure and, inversely, with smoking status and sex hormone-binding globulin. " 12/01/2001 - "AIMS: To assess whether sex hormone binding globulin (SHBG) is a potential marker for hyperinsulinaemia/insulin resistance in prepubertal obese children. " 01/01/2000 - "An association between sex hormone-binding globulin (SHBG) and insulin resistance expressed by the homeostasis model (HOMA-R), and the significance of both variables as risk factors for the development of type 2 diabetes were investigated in 483 Japanese-American subjects. " 01/01/2000 - "Association of sex hormone-binding globulin and insulin resistance among Japanese-American subjects." Order ALL the reference details at left...
5.	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 08/01/2008 - "TAAAAn polymorphism in sex hormone-binding globulin (SHBG) gene has been found to influence the transcriptional activity of SHBG gene in vitro, and several studies have reported variable associations of this polymorphism with serum SHBG levels in women with polycystic ovary syndrome (PCOS). " 04/01/2007 - "Role of D327N sex hormone-binding globulin gene polymorphism in the pathogenesis of polycystic ovary syndrome." 02/01/2007 - "Sex hormone-binding globulin expression in the endometria of women with polycystic ovary syndrome." 12/01/2003 - "Association of the (TAAAA)n repeat polymorphism in the sex hormone-binding globulin (SHBG) gene with polycystic ovary syndrome and relation to SHBG serum levels." 01/01/1996 - "OBJECTIVE: To quantify the actual serum free T with a specific new reference method in women with polycystic ovary syndrome (PCOS) and to analyze the effects of serum free T, total T, and the T:sex hormone-binding globulin (SHBG) ratio on the diagnosis of PCOS. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Testosterone (Sustanon)
2.	Insulin (Novolin)
3.	Androstenedione (4 Androstene 3,17 dione)
4.	Hormones
5.	Androgens
6.	Glucose (Dextrose)
7.	Gonadotropins
8.	Dehydroepiandrosterone Sulfate
9.	Gonadal Steroid Hormones (Sex Hormones)
10.	Dehydroepiandrosterone (DHEA)

Related Therapies and Procedures

1.	Vegetarian Diet (Vegetarianism)
2.	Transplantation (Transplant Recipients)
3.	Orchiectomy (Orchidectomy)
4.	Aftercare (After-Treatment)
5.	Drug Therapy (Chemotherapy)

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