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Serum Sickness

Immune complex disease caused by the administration of foreign serum or serum proteins and characterized by fever, lymphadenopathy, arthralgia, and urticaria. When they are complexed to protein carriers, some drugs can also cause serum sickness when they act as haptens inducing antibody responses.
Also Known As:
Serum Sicknesses; Sickness, Serum; Sicknesses, Serum
Networked: 620 relevant articles (18 outcomes, 44 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Hypersensitivity (Allergy)
2. Anaphylaxis (Anaphylactic Shock)
3. Infection
4. Fever (Fevers)
5. Arthralgia (Joint Pain)

Experts

1. Quigg, Richard J: 7 articles (05/2015 - 01/2005)
2. Alexander, Jessy J: 6 articles (05/2015 - 01/2005)
3. Chang, Anthony: 5 articles (05/2015 - 04/2007)
4. Jacob, Alexander: 4 articles (05/2015 - 04/2007)
5. Haas, Mark: 4 articles (09/2010 - 01/2005)
6. Isbister, Geoffrey K: 3 articles (01/2016 - 04/2005)
7. Ryan, Nicole M: 2 articles (01/2016 - 12/2015)
8. Chaves, Lee: 2 articles (07/2013 - 11/2012)
9. Mariette, Xavier: 2 articles (06/2013 - 03/2007)
10. Gottenberg, Jacques-Eric: 2 articles (06/2013 - 03/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Serum Sickness:
1. Antigen-Antibody Complex (Immune Complex)IBA
2. rituximab (Mabthera)FDA Link
3. Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA
4. AntibodiesIBA
5. MethylprednisoloneFDA LinkGeneric
6. Penicillins (Penicillin)FDA Link
7. Immunoglobulin M (IgM)IBA
8. Complement System Proteins (Complement)IBA
9. infliximab (Remicade)FDA Link
10. SteroidsIBA

Therapies and Procedures

1. Homologous Transplantation (Allograft)
2. Transplants (Transplant)
3. Platelet Transfusion (Blood Platelet Transfusions)
4. Injections
5. Immunotherapy