|1.||Agarwal, Shweta: 1 article (11/2015)|
|2.||Mehrotra, Ranjana: 1 article (11/2015)|
|3.||Ray, Bhumika: 1 article (11/2015)|
|4.||Mao, Qing: 1 article (04/2014)|
|5.||Wang, Xiang: 1 article (04/2014)|
|6.||You, Chao: 1 article (04/2014)|
|7.||Liu, Jin-Ping: 1 article (04/2014)|
|8.||Liu, Yan-Hui: 1 article (04/2014)|
|9.||Chen, Jin-Xiu: 1 article (04/2014)|
|10.||Sun, Jian: 1 article (01/2013)|
11/01/1976 - "Phase II study of methyl-CCNU in the treatment of advanced pancreatic carcinoma."
09/15/1984 - "Five of 53 patients with gallbladder carcinoma (2/18 [11%] on 5-FU, 2/16 [12%] on 5-FU + Stz, and 1/19 [5%] on 5-FU + MeCCNU) had objective response to treatment. "
12/15/1981 - "Semustine should be considered in the treatment of metastatic cloacogenic carcinoma."
12/15/1981 - "Response of metastatic cloacogenic carcinoma to treatment with semustine."
11/01/1977 - "5-Flourouracil (5-FU) and methyl-CCNU have demonstrated separate sensitivities in carcinoma of the large bowel. "
|2.||Rectal Neoplasms (Rectal Cancer)
04/01/1992 - "We conclude that MeCCNU is not an essential component of effective postoperative combined modality treatment of adjuvant rectal cancer."
08/01/1991 - "A large adjuvant trial in rectal cancer demonstrated improved survival and decreased local recurrences when fluorouracil and methyl-CCNU were added to radiation therapy."
01/01/1993 - "Postoperative administration of a combination of radiotherapy and chemotherapy (5-FU, methyl CCNU) also improved the survival rate and disease-free interval in patients operated for rectal cancer. "
02/01/1991 - "Several trials in rectal cancer show an advantage for 5-FU combined with semustine and radiation therapy in terms of disease-free survival, overall survival, or both; the contribution of semustine has been questioned and is currently being investigated. "
12/01/1989 - "Adjuvant therapy for rectal cancer: is 5-FU effective without MeCCNU."
|3.||Colorectal Neoplasms (Colorectal Cancer)
12/01/1977 - "This therapeutic trial of combined FU and MeCCNU, employing a dose-schedule distinct from but comparable to previous studies has failed to confirm the substantial response rate reported by other investigators and reinforces the need for exploring new drugs and combinations of drugs in advanced colorectal cancer. "
09/01/1979 - "Phase I-II study of ftorafur and methyl-CCNU in advanced colorectal cancer."
08/01/1979 - "Phase II evaluation of diglycoaldehyde, VP-16-213, and the combination of methyl-CCNU and beta-2'-deoxythioguanosine in previously treated patients with colorectal cancer: an Eastern Cooperative Oncology Group study (EST-1275)."
11/01/1977 - "This study was an attempt to see if methyl-CCNU versus methyl-CCNU plus 5-FU would demonstrate different responses in advanced colorectal carcinoma. "
04/01/1984 - "Patients with residual disease after palliative resection of colorectal cancer were randomly allocated to receive methyl CCNU and 5-Fluorouracil or followed conventionally. "
06/01/1983 - "A phase I study of weekly semustine was conducted in 32 patients with advanced cancer. "
12/01/1982 - "Nephrotoxicity in cancer patients who had received methyl-CCNU was not confirmed until about 6 years after clinical trials began. "
05/01/1985 - "Five of the six tumor lines examined showed either no response to MeCCNU or regrowth after an incomplete response. "
12/01/1983 - "Semustine is an investigational cancer chemotherapeutic agent in widespread use. "
01/01/1982 - "The oncostatic effect of methyl-CCNU on various experimental lymphoreticular neoplasms."
09/01/1977 - "A controlled study of 5-fluorouracil versus 5-fluorouracil and methyl-CCNU in advanced gastrointestinal adenocarcinoma."
04/01/1992 - "Radiation therapy and fluorouracil with or without semustine for the treatment of patients with surgical adjuvant adenocarcinoma of the rectum. "
01/01/1984 - "This prospective evaluation of 5-FU and methyl-CCNU administered in combination to patients with curative surgery for histologically proved colorectal adenocarcinoma is based upon 645 patients randomized between August 1973 and July 1979. "
09/15/1983 - "This prospective evaluation of 5-fluorouracil (5-FU) and methyl-CCNU administered in combination to patients with surgery for histologically proved gastric adenocarcinoma is based upon 312 patients randomized between August 1974 and May 1980. "
09/01/1979 - "Methyl-CCNU and Ftorafur does not appear to be an effective combination in advanced adenocarcinoma of the colon and rectum."
|1.||Drug Therapy (Chemotherapy)
|4.||Heterologous Transplantation (Xenotransplantation)