Self Administration (Administration, Self)

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577 relevant articles (19 outcomes, 89 trials/studies) found for this Therapy

Description: Administration of a drug or chemical by the individual under the direction of a physician. It includes administration clinically or experimentally, by human or animal.

Also Known As:

Administration, Self; Administrations, Self; Self Administrations

Relationship Network

Therapy Context: Research Results

Therapeutics: 5232

Drug Therapy: 116925

Self Administration: 577

Self Care: 22

Self Administration: 577

Experts

1.	Cubells, Joseph F: 2 articles (06/2007 - 02/2006)
2.	Malison, Robert T: 2 articles (06/2007 - 02/2006)
3.	Gueorguieva, Ralitza: 2 articles (06/2007 - 02/2006)
4.	Kalayasiri, Rasmon: 2 articles (06/2007 - 02/2006)
5.	Sughondhabirom, Atapol: 2 articles (06/2007 - 02/2006)
6.	Coric, Vladimir: 2 articles (06/2007 - 02/2006)
7.	Lynch, Wendy J: 2 articles (06/2007 - 02/2006)
8.	Brady, Anne Marie: 1 article (10/2008)
9.	Ewan, Eric: 1 article (10/2008)
10.	McCallum, Sarah E: 1 article (10/2008)

Related Diseases

1.	Substance-Related Disorders (Drug Abuse) 04/01/2001 - "CONCLUSIONS: The data of this study are consistent with the view that hypnotic self-administration by insomniacs is therapy-seeking behavior and not drug abuse." 09/01/1998 - "The uniform observation of predominant inhibition among the various electrophysiology studies is consistent with the heuristic value of anesthetized and slice recording methods in identifying potential neurophysiological correlates of drug taking; however, the existence of firing patterns (e.g., phasic increases) uniquely associated with self-administration behavior (and thus absent in anesthetized and slice studies), as well as the unique presence of the primary behavior of interest in studies such as the present one, underscores the importance of conducting electrophysiological investigations of drug taking and drug addiction in the self-administering animal in parallel with anesthetized and slice studies whenever possible." 12/19/1997 - "Further, because acquisition of drug self-administration is an animal model of vulnerability to drug addiction, these inbred strains may be useful to study factors underlying such vulnerability." 05/01/1997 - "Although accumbens DA is important for drug abuse phenomena, particularly stimulant self-administration, studies that involve other reinforcers are more problematic" 10/01/1994 - "To investigate new approaches for treatment of drug abuse, subcutaneous vascular ports were implanted in rhesus monkeys (Macaca mulatta) for use in drug self-administration studies" Order ALL the reference details at left...
2.	Cocaine-Related Disorders (Cocaine Addiction) 02/01/1997 - "In the present study, the behavioral effects of PTT were evaluated in two models of cocaine abuse: drug self-administration and drug discrimination" 10/01/2003 - "One approach for studying cocaine addiction has been to permit escalating patterns of self-administration (SA) by rats by prolonging daily drug availability" 07/01/2000 - "Alterations in neuroendocrine function associated with self-administration may be related to the development of cocaine dependence and could contribute to relapse in abstinent users." 01/01/1994 - "Use of rodent self-administration models to develop pharmacotherapies for cocaine abuse." 07/01/2008 - "The present paper (1) reviews the most commonly used human self-administration procedures, (2) discusses the concordance of subjective reports and self-administration within the context of medications development for substance use disorders, focusing primarily on illustrative examples from development efforts with opioid and cocaine dependence, and (3) explores the utility of applying self-administration procedures to assess the abuse liability of novel compounds, including "abuse-deterrent" formulations (ADFs)" Order ALL the reference details at left...
3.	Pain (Aches) 08/01/1989 - "During self-administration, the number of capsules taken increased (5 +/- 1.3 to 11.4 +/- 2.4; p less than 0.001), the frequency of bowel movements decreased (3.6 +/- 1.4 to 1.6 +/- 0.7; p less than 0.05), and the pain was also relieved significantly (2.2 +/- 0.7 to 1.1 +/- 0.7; p less than 0.05) when compared with the regular dosage" 10/01/2008 - "This review article focuses on the impact that the presence of pain has on drug self-administration in rodents, and the potential for using self-administration to study both addiction and pain, as well as their interaction" 10/01/2005 - "The objective of this study was to determine the extent of use of cannabis in the community for pain and other symptom relief, and its side effects during self-administration in patients with SCD" 10/01/2008 - "Chronic pain alters drug self-administration: implications for addiction and pain mechanisms." 10/01/2008 - "This paper introduces a patient version of the PDUQ (PDUQp), a 31-item questionnaire derived from the items of the original tool designed for self-administration, and describes evidence for its validity and reliability in a sample of patients with chronic nonmalignant pain and on opioid therapy" Order ALL the reference details at left...
4.	Body Weight (Weight, Body) 07/01/2002 - "Chronic food restriction and maintenance of low body weight have long been known to increase the self-administration and motor-activating effects of abused drugs" 03/01/1990 - "During these substitution periods, responding for self-administration, food intake and body weight were recorded" 10/01/1976 - "During the drug self-administration phases there was a marked increase in locomotor behavior and stereotypy along with a decrease in body weight; the rest periods were characterized by minimal activity" 11/21/1975 - "The learned taste aversion resulted from five 10-min self-administrations of alcohol mixed with an originally preferred flavor at a dosage of 1.69 g alcohol/kg body weight/day" 09/01/1981 - "Results indicated that (1) overall, self-administration rates were significantly greater for cocaine reinforced animals, (2) significantly higher rates of cocaine self-administration occurred in body weight reduced rats and (3) the operation of FT-1 schedule neither significantly enhanced or inhibited drug intake" Order ALL the reference details at left...
5.	Alcoholism (Alcohol Abuse) 08/01/2000 - "Studies of limited alcohol self-administration in the laboratory are an essential element in screening new medications for the treatment of alcoholism" 03/01/2008 - "For the self administration of treatment strategy, the variables significantly associated with treatment noncompliance were as follows: being an unregistered worker (relative risk [RR] = 3.06); retreatment (RR = 2.73); alcoholism (RR = 3.10); and no investigation of contacts (RR = 8.94)" 03/01/1999 - "Long-term alcohol self-administration with repeated alcohol deprivation phases: an animal model of alcoholism?" 01/01/1988 - "Identification of the environmental and biological variables that promote and maintain alcohol-seeking or alcohol self-administration behavior is key to our understanding of the disorder alcoholism itself." 11/01/1986 - "The importance of a history of self-administration of drugs intravenously was evaluated in 507 consecutive inpatient male primary alcoholics and primary drug abusers with secondary alcoholism" Order ALL the reference details at left...

Related Drugs and Biologics

1.	Cocaine (Cocaine HCl)
2.	Ethanol (Ethyl Alcohol)
3.	Morphine (MS Contin)
4.	Nicotine
5.	Heroin (Diamorphine)
6.	Dopamine Agonists (Dopamine Agonist)
7.	Naloxone (Narcan)
8.	Nitrous Oxide (Laughing Gas)
9.	Dopamine D1 Receptors (Dopamine D1 Receptor)
10.	Chloroquine (Aralen)

Related Therapies and Procedures

1.	Analgesia
2.	Drug Therapy (Chemotherapy)
3.	Patient-Controlled Analgesia (Analgesia, Patient Controlled)
4.	Chemoprevention
5.	Self Medication

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