Seizures (Seizure)

27884  relevant articles (2076 outcomes, 3107 trials/studies) found for this Disease

Seizure; Convulsions; Convulsion; Tonic-Clonic Seizure; Focal Seizures; Jacksonian Seizure; Clonic Seizure; Tonic Seizure; Tonic-Clonic Seizures; Convulsion, Non-Epileptic; Seizures, Auditory; Seizures, Clonic; Seizures, Gustatory; Seizures, Olfactory; Seizures, Somatosensory; Seizures, Tonic; Seizures, Tonic-Clonic; Seizures, Vertiginous; Seizures, Vestibular; Seizures, Visual; Auditory Seizure; Auditory Seizures; Clonic Seizures; Convulsion, Non Epileptic; Convulsions, Non-Epileptic; Convulsive Seizure; Focal Seizure; Generalized Seizure; Generalized Seizures; Gustatory Seizure; Gustatory Seizures; Motor Seizure; Motor Seizures; Non-Epileptic Convulsion; Non-Epileptic Convulsions; Olfactory Seizure; Olfactory Seizures; Seizure, Auditory; Seizure, Clonic; Seizure, Convulsive; Seizure, Focal; Seizure, Generalized; Seizure, Gustatory; Seizure, Jacksonian; Seizure, Motor; Seizure, Olfactory; Seizure, Sensory; Seizure, Somatosensory; Seizure, Tonic; Seizure, Tonic-Clonic; Seizure, Vertiginous; Seizure, Vestibular; Seizure, Visual; Seizures, Tonic Clonic; Sensory Seizure; Sensory Seizures; Somatosensory Seizure; Somatosensory Seizures; Tonic Seizures; Vertiginous Seizure; Vertiginous Seizures; Vestibular Seizure; Vestibular Seizures; Visual Seizure; Visual Seizures; Convulsive Seizures; Seizures, Convulsive; Seizures, Focal; Seizures, Generalized; Seizures, Motor; Seizures, Sensory

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Seizures (Seizure)
2.	Epilepsy (Aura)
3.	Syndrome
4.	Status Epilepticus (Complex Partial Status Epilepticus)
5.	Absence Epilepsy (Absence Seizure)
1074 Diseases and 10760 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Experts

1.	Luszczki, Jarogniew J: 27 articles (03/2008 - 10/2004)
2.	Czuczwar, Stanislaw J: 24 articles (03/2008 - 06/2002)
3.	Czuczwar, Stanisław J: 20 articles (11/2007 - 02/2002)
4.	Czuczwar, S J: 18 articles (05/2008 - 01/2000)
5.	Won, Moo Ho: 18 articles (09/2005 - 02/2002)
6.	Kang, Tae-Cheon: 17 articles (07/2007 - 06/2002)
7.	Borowicz, Kinga K: 15 articles (03/2008 - 03/2002)
8.	Kleinrok, Z: 14 articles (02/2004 - 01/2000)
9.	Dehpour, Ahmad Reza: 13 articles (09/2008 - 06/2002)
10.	Hwang, In Koo: 13 articles (06/2008 - 02/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Seizures:

1.	Anticonvulsants (Antiepileptic Drugs)IBA 12/01/2006 - "Antiepileptic drugs (AEDs) suppress seizures but appear to have little effect on long-term remission, and the choice of AED is for the most part arbitrary with most AEDs having a similar success rate when used as the first drug" 09/01/1999 - "With antiepileptic drugs, almost all had control of clinical seizures, and most improved in mental status" 09/01/1998 - "The treatment, consisting of 43 SCP training sessions and 22 behavioral control sessions, yielded a highly significant reduction of seizure frequency to about 7.5/week; such a decrease had never been observed after administration of new anticonvulsant drugs, nor after the callosotomy" 07/01/1994 - "The efficacy of these 12 antiepileptic drug occurs despite the fact that candidate antiepileptic drugs are evaluated under highly unfavourable conditions, namely as add-on therapy in patients refractory to drug management and with high seizure frequency" 01/01/1992 - "Apparently, tolerance to anticonvulsant drugs is most likely to transfer between drugs that are effective against similar kinds of clinical and experimental seizures and have similar putative mechanisms of action." Get all the results and reference details, order at left...
2.	Pentylenetetrazole (Metrazol)IBA 07/01/2000 - "Most of the compounds provided significant protection against maximal electroshock-induced seizures (MES) at 100 mg/kg after 0.5 h and at 300 mg/kg after 4 h in both MES and pentetrazole-induced (PTZ) seizures" 10/01/1990 - "Synthesis of both enantiomers of 29 and 39 indicated that the R isomers 30 and 40 were the most active and showed very good protection against MES, pentylenetetrazole, and mercaptopropionic acid induced seizures after oral administration in mice" 04/01/1987 - "Most pyrazolines (100 mg/kg) provided 20-80% protection against pentylenetetrazol-induced convulsions in mice" 01/01/1990 - "2-Ethylcyclohexanone was very effective against pentylenetetrazol seizures but did not prevent maximal electroshock seizures" 03/01/1983 - "Compared with PB, PEMA was 16 times less potent against electroshock and Metrazol seizures but only 8 times less toxic" Get all the results and reference details, order at left...
3.	Valproic Acid (Valproate, Semisodium)FDA LinkGeneric 10/01/2004 - "Divalproex ER also yielded improved seizure control and greater improvement of psychiatric symptoms, and was greatly preferred by patients over divalproex DR. Although the results of the current analyses must be considered highly tentative due to the open-label nature of the trials included, the findings do suggest broad clinical superiority of the new ER preparation." 03/01/1989 - "Numerous clinical studies have found valproate to be highly effective in controlling generalized seizures, particularly as monotherapy" 01/25/1988 - "Results of a retrospective study in 30 patients indicate that, contrary to the findings of some earlier studies, valproate monotherapy is highly effective in the treatment of partial seizures, especially those that become secondarily generalized" 08/01/2006 - "Prognosis in respect of long term seizure freedom is good with sodium valproate being the most effective medication" 09/01/2005 - "For patients with generalized seizures, valproate is most likely to be cost-effective for newly diagnosed patients" Get all the results and reference details, order at left...
4.	Carbamazepine (Tegretol)FDA LinkGeneric 07/01/2003 - "Carbamazepine is a well-established, effective treatment of complex partial seizures and is well tolerated in most patients" 01/01/1984 - "Carbamazepine is highly effective in blocking completed amygdala-kindled seizures, but does not block their development in the rat" 04/01/1979 - "Carbamazepine is an anticonvulsant most effective in treating complex partial and generalized tonic-clonic seizures" 02/01/1999 - "Carbamazepine is a potent anticonvulsant agent with proven efficacy in the treatment of partial and tonic-clonic seizures" 07/01/1996 - "Carbamazepine (Tegretol, CBZ) is an anticonvulsant drug that is very effective in the treatment of tonic-clonic seizures and is gaining acceptance as a treatment for various psychiatric disorders" Get all the results and reference details, order at left...
5.	Phenytoin (Dilantin)FDA LinkGeneric 03/11/2004 - "The study identified two PMHs, 14 (ED(MES(2.5)) = 28 +/- 2 mg/kg) and 12 (ED(MES(2.5)) = 39 +/- 4 mg/kg), to be the most active candidates of the series, which are comparable to phenytoin (55, ED(MES(2.5)) = 30 +/- 2 mg/kg) in their protection against seizure" 05/01/1999 - "Most patients were treated with phenytoin, which was well tolerated and effective in controlling seizures" 08/01/2008 - "Pretreatment with phenytoin (5 mg/kg) in combination with SMF had significantly greater effects on seizure latency and severity than either pretreatment alone" 02/01/2002 - "The intracerebral controlled-release of phenytoin resulted in a statistically significant reduction in seizure activity in the treatment group as evidenced by lower Racine scores" 07/01/1993 - "Depending on the stimulus protocol, phenytoin significantly reduced the severity of seizures or blocked the seizures completely throughout the 2-week period of treatment" Get all the results and reference details, order at left...
6.	Diazepam (Valium)FDA LinkGeneric 05/01/1989 - "Pretreatment with diazepam was found to be highly effective in reducing observed seizures from 90% to 0% and reducing the incidence of death from 85% to 10%" 03/01/1984 - "Diazepam was administered rectally as a new experimental suppository formulation immediately after a seizure and was highly effective in preventing recurrent fits within a 24 h observation period (p less than 0.001)" 04/01/1999 - "We found that diazepam is effective against seizures in 98% of cases, has a rapid onset of action and is safe" 03/01/1990 - "Diazepam (5.0 to 10.0 mg/kg) significantly reduced the incidence of clinically overt seizures but offered no protection against death" 12/01/1984 - "Continuous diazepam infusion has been used successfully to treat persistent seizure activity" Get all the results and reference details, order at left...
7.	Phenobarbital (Luminal)FDA Link 04/01/1998 - "A marked improvement could be observed for most of the patients treated with phenobarbitone in terms of reduction of seizure frequency although complete seizure control was achieved in only a few." 08/01/1977 - "Complete protection against IPS-induced seizures was observed for a period of 6 h after acute phenobarbital administration during which the mean plasma phenobarbital concentrations were between 16.2 +/- 0.91 and 13.6 +/- 1.0 microgram/lm" 12/01/2005 - "CONCLUSIONS: Phenobarbital in the dose of 20 mg/kg IV given within six hours of life to term and near-term neonates with HIE, significantly decreased the incidence of neonatal seizures and was well tolerated" 02/01/2000 - "Phenobarbital (12.5-50 mg/kg, subcutaneously) also significantly decreased the incidence of both convulsions and prolonged their latencies" 08/01/1999 - "The extract significantly potentiated the phenobarbitone sleeping time in mice and produced a 60% protection against leptazol-induced convulsion" Get all the results and reference details, order at left...
8.	lamotrigine (Lamictal)FDA LinkGeneric 03/01/1996 - "Efficacy measurements were comparable between the three treatment groups, although the higher lamotrigine dose was possibly most effective, with 60.4% completing seizure free compared with 51.3% (LTG 100) and 54.7% (CBZ 600)" 08/01/2008 - "In this study-the first large prospective investigation of the long-term tolerability and efficacy of an antiepileptic drug in a patient population 2 years and younger-lamotrigine administered for up to approximately 72 weeks was well tolerated and associated with good seizure control." 01/01/2001 - "The overall Peto's Odds Ratio (OR) and 95% confidence intervals (CIs) across all studies for 50% or greater reduction in seizure frequency was 2.71 (1.87, 3.91) indicating that lamotrigine is significantly more effective than placebo in reducing seizure frequency" 01/01/2000 - "The overall Peto's Odds Ratio (OR) and 95% confidence intervals (CIs) across all studies for 50% or greater reduction in seizure frequency was 2.71 (1.87, 3.91) indicating that lamotrigine is significantly more effective than placebo in reducing seizure frequency" 11/10/1999 - "RESULTS: Compared with placebo, lamotrigine significantly reduced the frequency of all partial seizures and the frequency of secondarily generalized partial seizures in these treatment-resistant patients" Get all the results and reference details, order at left...
9.	N-Methylaspartate (NMDA)IBA 04/08/2002 - "NMDA antagonists derived from 5-phosphonomethyl-1,4-dihydroquinoxaline-2,3-dione (3a) are potent anticonvulsant agents, and display strong protective effects in the electroshock-induced convulsion assay in mice" 11/16/1993 - "Prior administration of CPA resulted either in a delay of seizure onset and unchanged mortality (0.5 mg/kg CPA, 60 mg/kg NMDA) or in elimination of tonic episodes and a significant reduction in postictal mortality (1, 2 mg/kg CPA; 60, 125 mg/kg NMDA)" 04/01/1990 - "We report experiments performed to determine if NMDA receptor antagonists are effective in stopping seizures in the late stages of SE" 09/25/2008 - "Here, we evaluated the protective efficacy of [+]-Hup A for NMDA-induced seizure in a rat model" 03/31/2000 - "Intraperitoneal (i.p.) administration of either 7ClKynA-D-glucopyranos-6'-ylester (7ClKynA/Glu6) or 7ClKynA-D-glucopyranos-3'-yl ester (7ClKynA/Glu3) was protective against seizures induced by N-methyl-D-aspartate (NMDA) in mice, with the former drug showing the highest anticonvulsive activity" Get all the results and reference details, order at left...
10.	topiramate (Topamax)FDA Link 01/01/2005 - "The results confirmed the earlier data received by the authors that topamax was most effective in generalized convulsive, partial and secondary generalized seizures" 10/01/1997 - "FINDINGS: Topiramate is highly effective in the control of previously therapy-resistant partial seizures, with or without secondary generalization" 01/01/2006 - "During topamax treatment, a complete remission was achieved in 48% patients, reduction of seizures frequency (more than by 50%)--in 44% patients" 09/01/2001 - "Topiramate (TPM) is a new anti-epileptic drug with proven efficacy against partial seizures in adults" 01/01/2000 - "Topiramate is a new anti-epileptic drug with proven efficacy against partial seizures in adults" Get all the results and reference details, order at left...
4399 Drugs and Important Bio-Agents and 25824 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 06/01/2000 - "The best independent predictors of remission are absence of organic brain damage, low intensity seizure propensity and good early effect of drug therapy" 04/01/2002 - "A 12-year-old girl who had been diagnosed with ALL and undergone chemotherapy presented with generalized tonic-clonic seizure while in complete remission" 06/01/1994 - "About half of the remaining patients can obtain improved seizure control with combination antiepileptic drug therapy, but usually with more adverse effects" 05/01/2001 - "CONCLUSION: The provision of safe and effective drug therapy to elderly patients requires an understanding of the unique age-related changes' in the pharmacokinetics and pharmacodynamics of AEDs as well as an appreciation of common seizure types and the drugs that are effective for the specific types seen in the elderly." 07/01/2008 - "Our results signify that no matter how many antiepileptic drug therapies have failed, there is always hope of a meaningful seizure remission in this population" Get all the results and reference details, order at left...
2.	Hemispherectomy 08/01/2006 - "Hemispherectomy/hemispherotomy is the most effective treatment to control seizure, and it also seems to provide good results on the psychomotor development when performed early, as demonstrated by the literature review and by the reported personal series reported here (20 children)" 11/01/1989 - "Hemispherectomy was performed in two children with sudden and complete recovery from seizures and improvement in psychomotor development" 08/01/2006 - "The efficacy of functional hemispherectomy procedures in achieving seizure freedom appears to be at least as good compared to resective procedures" 04/01/2005 - "Eleven patients underwent functional hemispherectomy, which resulted in fairly good seizure control and improved development" 08/01/1999 - "Hemispherectomy procedures are performed in patients for whom focal cortical resection would be predicted to produce a significant reduction in seizures" Get all the results and reference details, order at left...
3.	Electrodes (Electrode) 08/01/1996 - "CONCLUSION: We have found intracerebral electrode placement to be as safe as subdural strip electrode placement and have found combined depth and strip electrode monitoring to be highly effective in localizing the onset zones of complex partial seizures" 02/01/2007 - "CONCLUSIONS: Implantation of electrodes in the ANT and subsequent stimulation is associated with a significant reduction in seizure frequency" 08/01/1998 - "However, in patients with CD, the presence of balloon cells was associated with significantly greater seizure frequency (p=0.009), and a significantly greater number of electrodes recording continuous frequent spiking (p=0.03)" 11/01/1991 - "The statistically significant results support the view that a pulsatile square wave stimulus is effective in inducing convulsions, provided that the d'Elia and not the Muller unilateral electrode placement is used" 03/01/1996 - "Ictal EEG indices show promise for separating individual ECT seizures on the basis of treatment electrode placement (ELPL), relative stimulus intensity (Dose), and expected therapeutic response" Get all the results and reference details, order at left...
4.	Aftercare (After-Treatment) 10/01/2005 - "One patient experienced a decline in gelastic seizure frequency nine months after treatment (Engle Class II) without significant reduction in aggressive behavior" 04/01/1997 - "Patients with good seizure outcome experience improved health-related quality of life after treatment" 01/15/2004 - "The efficacy of treatment was measured as the decrease in the number of seizures after treatment" 09/01/2008 - "We found no difference between the ALB and placebo groups in symptoms during treatment or in seizure recurrence during the 12 months after treatment" 07/01/2008 - "If a patient does not awaken after treatment, urgent electroencephalogram (EEG) should be obtained to rule out nonconvulsive seizure activity" Get all the results and reference details, order at left...
5.	Anesthesia 11/01/2005 - "Postoperative convulsion incidents were extracted from the Thai Anesthesia Incidents Study (THAI Study) database in terms of demographic data, details of events, outcome, contributing factors related to anesthesia and corrective strategies" 11/01/2005 - "The Thai Anesthesia Incidents Study (THAI Study) of perioperative convulsion." 11/01/2008 - "Seizures may falsely elevate electroencephalogram indices of depth of anesthesia." 11/01/2008 - "These seizures most commonly occur during induction or emergence from anesthesia, when the anesthetic drug concentration is relatively low" 03/01/2008 - "We then examine what has been learned by studying global changes in the level of consciousness, such as sleep, anesthesia, and seizures" Get all the results and reference details, order at left...
286 Therapies and Procedures and 3452 more articles analyzed in the Full Patient-Physician Summary Report, order at left...