|1.||Congenital Abnormalities (Deformity)
|5.||Syringomyelia (Morvan's Disease)
|1.||Qiu, Yong: 85 articles (10/2015 - 06/2005)|
|2.||Lenke, Lawrence G: 43 articles (07/2015 - 01/2002)|
|3.||Wang, Bin: 40 articles (01/2015 - 12/2005)|
|4.||Negrini, Stefano: 38 articles (12/2015 - 01/2006)|
|5.||Zhu, Feng: 35 articles (05/2015 - 01/2006)|
|6.||Yu, Yang: 33 articles (11/2014 - 12/2005)|
|7.||Weiss, Hans-Rudolf: 30 articles (10/2015 - 01/2002)|
|8.||Sun, Xu: 30 articles (10/2015 - 03/2007)|
|9.||Bridwell, Keith H: 30 articles (12/2014 - 01/2002)|
|10.||Zaina, Fabio: 28 articles (12/2015 - 01/2008)|
|1.||Morphine (MS Contin)FDA LinkGeneric
03/01/2001 - "This study was designed to assess the postoperative analgesic effect of low-dose intrathecal morphine after scoliosis surgery in children. "
01/01/2014 - "The authors hypothesized that the PCA ratio is able to predict morphine requirement in the first 24 hours after scoliosis surgery. "
03/01/2013 - "These data demonstrate that intrathecal morphine in pediatric surgical scoliosis correction significantly decreases intra-operative blood loss and transfusions and enhances blood pressure stability."
03/01/2013 - "This retrospective cohort study was designed to assess the impact of intrathecal morphine compared with no intrathecal morphine on blood loss and on hemodynamic stability during surgery for pediatric idiopathic scoliosis correction. "
03/01/2013 - "Intrathecal morphine reduces blood loss during idiopathic scoliosis surgery: retrospective study of 256 pediatric cases."
|2.||6-Aminocaproic Acid (6 Aminocaproic Acid)FDA LinkGeneric
11/15/2008 - "Amicar was highly effective in decreasing perioperative blood loss and transfusion requirements in patients with neuromuscular scoliosis undergoing PSF and SSI. "
09/15/2008 - "Amicar was highly effective in decreasing total perioperative blood loss and transfusion requirements in same-day ASF and PSF with SSI for idiopathic scoliosis. "
02/01/2004 - "A prospective, randomized, double-blind Institutional Review Board-approved study evaluating the efficacy of Amicar (epsilon aminocaproic acid), an antifibrinolytic agent, in decreasing perioperative blood loss in idiopathic scoliosis. "
05/15/2001 - "A prospective study evaluating the efficacy of epsilon-aminocaproic acid (EACA) in decreasing perioperative blood loss in idiopathic scoliosis. "
09/01/2005 - "Four separate studies on the role of Amicar in decreasing perioperative blood loss in idiopathic scoliosis. "
08/01/2015 - "The vertical expandable prosthetic titanium rib may be beneficial for those patients with congenital scoliosis and fused ribs and thoracic insufficiency syndrome. "
09/01/2013 - "The vertical expandable prosthetic titanium rib (VEPTR(®)) appears to be beneficial for patients with congenital scoliosis and fused ribs, and thoracic Insufficiency Syndrome. "
04/01/2007 - "Vertical expandable prosthetic titanium rib (VEPTR), which is not considered a true growing rod system, is particularly effective in congenital scoliosis with fused ribs. "
09/01/2010 - "The titanium rib procedure is a safe and effective way of surgically treating pediatric patients with thoracic insufficiency syndrome and scoliosis. "
04/01/2009 - "Bilateral use of the vertical expandable prosthetic titanium rib attached to the pelvis: a novel treatment for scoliosis in the growing spine."
|4.||Tranexamic Acid (AMCA)FDA Link
07/01/2015 - "The aim of this study was to compare transfusion requirements in patients before and after the introduction of tranexamic acid as standard in patients undergoing spinal surgery for idiopathic scoliosis in a national orthopaedic hospital. "
01/01/2015 - "Use of Tranexamic Acid (TXA) on reducing blood loss during scoliosis surgery in Chinese adolescents."
06/01/2013 - "The effect of tranexamic acid in blood loss and transfusion volume in adolescent idiopathic scoliosis surgery: a single-surgeon experience."
04/01/2009 - "Tranexamic acid (TXA) has been investigated in these patient groups but consensus with respect to the dosing regimen has not been achieved, especially in the pediatric scoliosis literature. "
04/01/2005 - "Intraoperative administration of tranexamic acid significantly reduces blood loss during spinal surgery in children with scoliosis."
|5.||Fibrinogen (Factor I)FDA Link
04/01/2011 - "The results indicate that preoperative fibrinogen concentration is a limiting factor for postoperative hemostasis during and after scoliosis surgery. "
02/01/2007 - "We subsequently measured fibrinogen levels on all postoperative days in 21 consecutive patients with idiopathic scoliosis and found a dramatic increase throughout the postoperative hospitalization. "
08/01/2015 - "In this prospective, randomised, clinical trial, patients aged 6 months to 17 yr undergoing craniosynostosis and scoliosis surgery received fibrinogen concentrate (30 mg kg(-1)) at two predefined intraoperative fibrinogen concentrations [ROTEM(®) FIBTEM maximum clot firmness (MCF) of <8 mm (conventional) or <13 mm (early substitution)]. "
04/01/2011 - "To investigate the potential association between fibrinogen, bleeding, and transfusion requirements after scoliosis surgery. "
04/01/2011 - "Preoperative fibrinogen plasma concentration is associated with perioperative bleeding and transfusion requirements in scoliosis surgery."
07/01/2015 - "Distractible spinal growth rods are the gold standard when treating early-onset scoliosis (EOS). "
07/01/2014 - "To determine whether there is improvement in pulmonary function in children with early-onset scoliosis (EOS) using magnetic growth rods (MGRs). "
10/01/2012 - "Serial casting has demonstrated efficacy for idiopathic early-onset scoliosis (EOS). "
06/01/2015 - "The aim of this retrospective clinical study is to evaluate the effect of growing rod lengthening technique on sagittal balance in relationship with the spinopelvic parameters, in early onset scoliosis (EOS). "
12/01/2015 - "Early-onset scoliosis (EOS) can have negative effects on the developing thorax, lungs, and quality of life in general. "
|7.||Anti-Bacterial Agents (Antibiotics)IBA
08/17/2002 - "After treatment with antibiotics, rest and gradual mobilisation, the girl retained a scoliosis; the boy was cured without residual complaints or abnormalities. "
08/01/2013 - "The wound healing is adequate without using drain for patients with idiopathic scoliosis who underwent posterior spinal fusion and instrumentation when good wash, watertight closure technique and appropriate antibiotics coverage is provided."
02/01/2008 - "Postoperative infection after the surgical treatment of idiopathic scoliosis can successfully be treated with irrigation and debridement, instrumentation removal, and a course of antibiotics. "
10/01/2008 - "The incidence of deep wound infection after spinal fusion in 220 children with CP scoliosis decreased from 15% to 4% with the use of prophylactic antibiotics in the corticocancellous allograft bone."
09/01/2007 - "To analyze the outcome of vacuum-assisted wound closure (VAC) in combination with antibiotics for the treatment of deep wound infection after instrumented spinal fusion in pediatric neuromuscular scoliosis. "
|8.||Aprotinin (Trasylol)FDA Link
12/01/2008 - "At out institution, the use of aprotinin is safe and cost effective for patients with neuromuscular scoliosis."
01/01/2015 - "The systematic review and meta-analysis indicated that aprotinin, TXA, and EACA all significantly reduced perioperative blood loss and transfusion requirements in scoliosis surgery. "
12/01/2008 - "Aprotinin in pediatric neuromuscular scoliosis surgery."
09/01/2003 - "Although the difference was not significant statistically, the benefit of aprotinin in reducing blood loss in spinal surgery for idiopathic scoliosis was consistent."
12/01/2008 - "Aprotinin (Trasylol), Bayer), an antifibrinolytic, has proven to be effective in reducing blood loss in cardiac and liver surgery, but little data exists in patients undergoing spinal fusion for neuromuscular scoliosis. "
|9.||Antifibrinolytic Agents (Antifibrinolytics)IBA
05/21/2014 - "The relative efficacy of antifibrinolytics in adolescent idiopathic scoliosis: a prospective randomized trial."
01/01/2015 - "We conducted a systematic review and meta-analysis for randomized controlled trials (RCTs), retrospective case-control studies, and retrospective cohort studies on the use of antifibrinolytic agents in scoliosis surgery by searching in the MEDLINE and EMBASE databases and the Cochrane Database of Systematic Reviews and Controlled Trials of papers published from January 1980 through July 2014. "
01/01/2008 - "We included blinded or unblinded randomized controlled trials that evaluated the effect of antifibrinolytics on perioperative blood loss in children that were 18 years of age or younger and undergoing scoliosis surgery. "
01/01/2015 - "Efficacy and Safety of Antifibrinolytic Agents in Reducing Perioperative Blood Loss and Transfusion Requirements in Scoliosis Surgery: A Systematic Review and Meta-Analysis."
01/01/2008 - "Antifibrinolytic agents for reducing blood loss in scoliosis surgery in children."
06/01/2006 - "For patients with idiopathic scoliosis, predonation with or without the addition of erythropoietin is a safe and effective way to avoid the use of allogenic blood products. "
11/15/2007 - "A recent study at our institution demonstrated the efficacy of rhEPO in pediatric idiopathic scoliosis patients, but suggested the possibility of an "erythropoietin resistance" in the pediatric neurogenic scoliosis population. "
11/15/2007 - "Efficacy of preoperative erythropoietin administration in pediatric neuromuscular scoliosis patients."
11/15/2007 - "The purpose of this study is to investigate this finding further by analyzing the effect of recombinant human erythropoietin (rhEPO) on hematocrit, transfusion and complication rates, and the length of intensive care unit (ICU) days in patients with neurogenic scoliosis. "
10/01/2004 - "Twenty-three consecutive patients undergoing spinal surgery for scoliosis received 6 administrations of 10000U of recombinant human erythropoietin (rHuEpo). "
|1.||Spinal Fusion (Spondylosyndesis)
03/01/2002 - "The most effective treatment for severe scoliosis is prevention by intervening with early spinal fusion utilizing segmental instrumentation as soon as curves are ascertained and before the onset of severe pulmonary or cardiac dysfunction."
12/03/2013 - "A combination of selective segmental TLIF and posterior spinal fusion is both safe and effective for degenerative scoliosis and excellent long-term clinical outcomes may be achieved. "
12/01/2015 - " children with significant scoliosis and CP classified within GMFCS levels 4 and 5, spinal fusion was associated with an improvement in activity and participation, whereas nonoperative treatment was associated with a small reduction. "
06/01/2012 - "Early onset scoliosis associated with SMA has been successfully treated with growing rod constructs, and posterior spinal fusion can be used in older children. "
07/01/2006 - "Ventral derotation spondylodesis, according to Zielke, achieves good results in operative treatment of idiopathic thoracic scolioses. "
01/01/2014 - "Our study confirmed that conservative treatment with brace is highly effective in treating juvenile idiopathic scoliosis, in particular most patients reaching a complete curve correction and only 4.9% of patients need surgery."
02/01/2014 - "Consensuses by the international Society on Scoliosis Orthopedic and Rehabilitation Treatment (SOSORT) show that there is no agreement among experts either on the best braces or on their biomechanical action, and that compliance is a matter of clinical more than patients' behavior (there is strong agreement on the management criteria to achieve best results with bracing). "
01/01/2011 - "Milwaukee brace 23-hours wearing protocol was most effective for the treatment of adolescent idiopathic scoliosis. "
05/01/2008 - "Milwaukee brace 23-hours wearing protocol was most effective for the treatment of adolescent idiopathic scoliosis. "
08/01/1991 - "The leg:spine ratio comparisons of scoliosis groups against normals showed that brace and fusion groups had highly significantly greater ratios at first visit and at maturity, using uncorrected spinal length. "
01/01/2015 - "In the treatment of severe scoliosis, preoperative head traction of several weeks' duration has proven a safe and effective method of correcting the malposition, and will also make scoliosis surgery technically easier. "
07/01/2011 - "The aim of this study was to investigate the feasibility and clinical efficacy of treatment of adolescent idiopathic scoliosis of >100° via posterior-only surgery with strong halo-femoral traction and posterior wide release. "
02/01/2015 - "Overall Scoliosis Research Society-22 questionnaire scores improved significantly pretraction versus postoperatively, but there was no change after traction versus before traction. "
09/15/2006 - "Intraoperative use of halo-femoral traction during the surgical treatment of patients with nonambulatory neuromuscular scoliosis provided significantly improved lumbar curve and pelvic obliquity correction. "
04/15/2013 - "Intraoperative skull-femoral traction can be a safe and effective method to assist correction of severe and rigid scoliosis. "
|4.||Orthotic Devices (Orthosis)
07/01/1992 - "Although improvement in the scoliosis averaged only 15 degrees, the major advantage of this orthosis was a marked improvement in sitting stability in 80% of patients."
01/01/2011 - "Conservative treatment with Chêneau orthosis and physiotherapy was effective in halting scoliosis progression in 48.1% of patients. "
07/01/2008 - "Efficacy of a new computer-aided design/computer-aided manufacture orthosis in the treatment of adolescent idiopathic scoliosis."
01/01/2001 - "Recent studies notwithstanding, the question of the efficacy of orthoses in idiopathic scoliosis remains unresolved."
06/01/1993 - "This study raises questions about the efficacy of spinal orthoses in modifying the natural history of late-onset idiopathic scoliosis and removes the ethical problems inherent in a prospective trial in which the only treatment permitted to the control group is surgery."
10/01/2015 - "Newer surgical techniques for scoliosis correction make the epidural space more accessible, but postsurgical changes may still alter the efficacy of neuraxial labor analgesia. "
10/01/2015 - "All women with previous spinal instrumentation surgery for scoliosis correction who requested neuraxial labor analgesia at Prentice Women's Hospital during the study period were approached. "
10/01/2015 - "Small studies (9-21 patients), conducted 10 to 20 years ago, demonstrated successful neuraxial labor analgesia in only 50% to 66% of patients with surgical correction for scoliosis. "
07/01/2015 - "The purpose of this study is to describe the duration of analgesia in children undergoing surgical correction of idiopathic scoliosis. "
10/01/2015 - "The findings of this investigation suggest that previous surgery for scoliosis repair does not affect neuraxial labor analgesia consumption, but performance of the neuraxial technique is more difficult. "