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Sciatica (Sciatic Neuralgia)

A condition characterized by pain radiating from the back into the buttock and posterior/lateral aspects of the leg. Sciatica may be a manifestation of SCIATIC NEUROPATHY; RADICULOPATHY (involving the SPINAL NERVE ROOTS; L4, L5, S1, or S2, often associated with INTERVERTEBRAL DISK DISPLACEMENT); or lesions of the CAUDA EQUINA.
Also Known As:
Sciatic Neuralgia; Sciatica, Bilateral; Bilateral Sciatica; Bilateral Sciaticas; Neuralgias, Sciatic; Sciatic Neuralgias; Neuralgia, Sciatic
Networked: 745 relevant articles (85 outcomes, 126 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Low Back Pain (Lumbago)
2. Pain (Aches)
3. Prolapse
4. Back Pain (Backache)
5. Radiculopathy (Radiculopathy, Cervical)

Experts

1. Karppinen, Jaro: 12 articles (03/2010 - 01/2002)
2. Koes, Bart W: 11 articles (05/2015 - 01/2006)
3. Peul, Wilco C: 10 articles (05/2015 - 01/2006)
4. Arts, Mark P: 8 articles (05/2015 - 01/2006)
5. Brand, Ronald: 8 articles (05/2015 - 01/2006)
6. Ala-Kokko, Leena: 7 articles (11/2008 - 01/2002)
7. Malmivaara, Antti: 7 articles (11/2006 - 01/2002)
8. Tervonen, Osmo: 6 articles (11/2006 - 01/2002)
9. Seitsalo, Seppo: 6 articles (11/2006 - 01/2003)
10. Hilde, G: 6 articles (01/2006 - 01/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Sciatica:
1. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
2. Chymopapain (Chymodiactin)FDA Link
3. TNFR-Fc fusion protein (etanercept)FDA Link
4. Adrenal Cortex Hormones (Corticosteroids)IBA
5. SteroidsIBA
6. Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
7. meloxicam (Mobic)FDA LinkGeneric
8. infliximab (Remicade)FDA Link
9. MethylprednisoloneFDA LinkGeneric
10. Lidocaine (Xylocaine)FDA LinkGeneric

Therapies and Procedures

1. Injections
2. Diskectomy (Discectomy)
3. Intervertebral Disk Chemolysis (Discolysis)
4. Epidural Injections
5. Traction