Schistosomiasis japonica

08/01/1993 - "Clinical trials in three endemic areas of Schistosomiasis japonica indicated that the therapeutic efficacy of levo-praziquantel is superior to racemic praziquantel. "
09/01/1991 - "The result of a randomized double blind comparison of therapeutic efficacy of single doses of levo-praziquantel (L-PZQ) and praziquantel (PZQ) in the treatment of 139 matched pairs of proved cases of schistosomiasis japonica was reported, 268 were chronic early cases and 10 were late cases. "
09/01/1991 - "A randomized double-blind study comparing the therapeutic efficacy of single dose of levo-praziquantel and mixed isomer praziquantel was carried out on 139 matched pairs of patients with schistosomiasis japonica. "
09/01/1991 - "Comparison of the therapeutic efficacy and side effects of a single dose of levo-praziquantel with mixed isomer praziquantel in 278 cases of schistosomiasis japonica."
01/01/2021 - "Praziquantel (PZQ) treatment for Schistosoma japonicum infection in pregnant women has been demonstrated to be safe and effective. "

12/01/2003 - "This indicates that the pcDNA3.1-SjC23 DNA vaccine can induce partial protection against Schistosoma japonicum infection in C57BL/6 mice."
12/12/2001 - "Vaccination of mice with a cocktail DNA vaccine induces a Th1-type immune response and partial protection against Schistosoma japonicum infection."
02/28/2005 - "To investigate the effect of immunostimulatory sequence on SjC23 DNA vaccine against Schistosoma japonicum infection. "
02/28/2005 - "[Enhancement of the protective effect of SjC23 DNA vaccine against Schistosoma japonicum infection by immunostimulatory sequence]."
01/01/2014 - "PAMAM-Lys, a novel vaccine delivery vector, enhances the protective effects of the SjC23 DNA vaccine against Schistosoma japonicum infection."

04/30/2012 - "To obtain promising antigens for diagnosis or therapeutic efficacy assessment of schistosomiasis japonica. "
09/01/1982 - "Efficacy of purified schistosoma japonicum egg antigens for ELISA serodiagnosis of human Schistosomiasis japonica: specificity and sensitivity."
10/01/2012 - "[Study on immune status of patients with schistosomiasis japonica in Poyang Lake region I characterization of antigen-specific antibody isotype responses to Schistosoma japonicum]."
07/01/1999 - "This study provides a valuable reference for further study on the immunity stimulated by the 22.6 kDa tegumental antigen in the murine model and a natural bovine host of Schistosomiasis japonica."
01/01/1995 - "Collaborative study on detection of circulating antigens in schistosomiasis japonica."

08/16/2018 - "The study confirms the potential of SjAChE as a vaccine/drug candidate against zoonotic schistosomiasis japonica."
01/01/2012 - "Results of our study suggest that novel genes, SJCWL05 and SJCWL06, are potential vaccine candidates against schistosomiasis japonica."
03/01/1993 - "Four laboratory tests and one field trial with cryopreserved irradiated (CI) schistosomula vaccine and a freeze-thaw (F/T) vaccine against bovine Schistosomiasis japonica were carried out in 1979 and 1980 with the following results: (1) Single intradermal vaccination in buffalo calves each with 10,000 20 krad CI Schistosomula plus 1 ml BCG gave 62% worm reduction (P < 0.05). "
08/01/2022 - "Therefore, rSjAAP may not be suitable to act as a potential vaccine candidate against schistosomiasis japonica in mice. "
01/01/2022 - "Our work represents a group of novel schistosome immunogens, which may be promising schistosomiasis japonica diagnosis and vaccine candidates."

06/01/2014 - "Serodiagnosis of Schistosoma japonicum infection: genome-wide identification of a protein marker, and assessment of its diagnostic validity in a field study in China."
08/01/2011 - "To study whether rSj26-Sj32 fusion protein can be used for diagnosis of chronic schistosomiasis japonicum. "
08/01/2011 - "[Study on diagnosis of chronic schistosomiasis japonicum with rSj26-Sj32 fusion protein]."
02/28/2011 - "To study the diagnostic value of the Dot ELISA with rSj26-Sj32 fusion protein for chronic schistosomiasis japonica. "
01/01/2020 - "Preliminary evaluation of the diagnostic potential of Schistosoma japonicum extracellular vesicle proteins for Schistosomiasis japonica."

01/01/2000 - "To evaluate the specificity and sensitivity of SjMAg in detecting specific antibodies in sera of patients with schistosomiasis japonica and in assessing therapeutic efficacy. "
01/01/2015 - "Moreover, Tfh2 cells, which were reported to be a specific subpopulation to facilitate the generation of protective antibodies, were increased more greatly than other subpopulations of total peripheral memory Tfh cells in patients with schistosomiasis japonica. "
06/01/2011 - "japonicum were detected by magnetic particle affinity immunoassay (MPAIA) in 158 cases of schistosomiasis japonica and 100 health persons, and their serum antibodies to S. "
10/01/2002 - "The detection of specific antibodies in saliva can be used as a non-invasive immunodiagnosis method of Schistosomiasis japonica."
10/01/2002 - "Non-invasive immunodiagnosis of Schistosomiasis japonica: the detection of specific antibodies in saliva."

09/01/2010 - "Whether the prophylactic efficacy of artesunate on Schistosomiasis japonica decreased after being used over 10-year period was still unknown. "
01/01/2001 - "[Studies on the preventive effect of artesunate against Schistosoma japonicum infection]."
11/01/1996 - "Studies on prophylactic effect of artesunate on schistosomiasis japonica."
01/01/2000 - "[The effect of artesunate in preventing the populations from Schistosoma japonicum infection during flood-control]."
01/01/1999 - "[Field application of oral artesunate for preventing Schistosoma japonicum infection]."

01/01/1948 - "The control of schistosomiasis japonica; studies on the value of repellents and repellent ointments as a protection against schistosomiasis japonica."
08/01/1952 - "IV. Two ointments for protection against schistosomiasis japonica."

07/01/2017 - "The potential to detect parasite DNA in urine and saliva has important practical implications for large-scale epidemiological screening programmes in the future, particularly in terms of logistical convenience, and the assay has the potential to be a valuable additional tool for the diagnosis of schistosomiasis japonica."
06/01/2013 - "[DNA prime followed by protein boost enhances the protective efficacy against Schistosoma japonicum infection in mice]."
01/01/2016 - "Optimisation of a droplet digital PCR assay for the diagnosis of Schistosoma japonicum infection: A duplex approach with DNA binding dye chemistry."
12/01/2009 - "DNA vaccination by electroporation and boosting with recombinant proteins enhances the efficacy of DNA vaccines for Schistosomiasis japonica."
09/23/2023 - "Hepatic schistosomula proteins previously identified based on second-generation schistosome DNA sequencing were found to hold excellent potential for schistosomiasis japonica diagnosis and as vaccine candidates. "

03/01/1975 - "Long-term efficacy of tubercidin against schistosomiasis japonica and mansoni in primates."
01/01/1974 - "Comparative efficacy of one and two treatments with tubercidin against Schistosomiasis japonica in monkeys."

01/15/2018 - "[Changes of serum anti-schistosome antibody levels in schistosomiasis japonica patients after treatment]."
07/01/1993 - "Regression of hepatic lesions after treatment of Schistosoma mansoni or Schistosoma japonicum infection in mice: a comparative study."
12/01/1984 - "Clinical study on cerebral schistosomiasis japonica on Leyte Island, Philippines: follow-up study 6 years after treatment with antischistosomal drugs."
12/01/1983 - "Immunologic function in schistosomiasis japonica patients before and after treatment."
01/15/2018 - "To investigate the changes of serum anti-schistosome antibody titers in schistosomiasis japonica patients after treatment, in order to provide the evidence for formulating the schistosomiasis surveillance program in marshland and lake regions. "

03/01/1962 - "[EXPERIMENTAL THERAPY OF SCHISTOSOMIASIS JAPONICA. "
01/01/1984 - "[Experimental therapy of hepatic fibrosis in schistosomiasis japonica. "
12/01/1986 - "Comparative efficacy of praziquantel and its optic isomers in experimental therapy of schistosomiasis japonica in rabbits."
07/01/1980 - "[Efficacy and toxicity of an indane compound, S75029 in experimental therapy of Schistosomiasis japonica (author's transl)]."
10/01/1962 - "XXVIII. TOXICITY AND EXPERIMENTAL THERAPY FOR SCHISTOSOMIASIS JAPONICA OF DIPTEREX]."

10/01/2008 - "This is the first report of a randomized, double-blind, placebo-controlled trial for evaluating combined chemotherapy with AM and two different dosages (60 mg/kg and 120 mg/kg) of PZQ in the treatment of acute schistosomiasis japonica in China. "
11/01/1946 - "Studies on schistosomiasis japonica; chemotherapy of experimental schistosomiasis japonica."
01/01/2023 - "P96 is a promising drug candidate for chemotherapy of schistosomiasis japonica, which has broad spectrum of action against various developmental stage, potentially addressing the deficiency of PZQ. "
08/01/2014 - "Mathematical modelling has shown that control options targeting the various transmission pathways of schistosomiasis japonica and incorporating bovine vaccination, mass human chemotherapy and mollusciciding could lead to its elimination from P.R. "
09/01/2011 - "The results demonstrate that an integrated schistosomiasis japonica control strategy focusing on the main transmission cycles and reservoirs and combines chemotherapy, infrastructure interventions and health education combined with robust surveillance is feasible and allows to effectively control S. "

12/25/1956 - "Studies on the therapy of schistosomiasis japonica. "
12/25/1956 - "Studies on the therapy of schistosomiasis japonica. "
11/01/1984 - "A case of schistosomiasis japonica: resolution of CAT-scan detected cerebral abnormalities without specific therapy."
08/01/1994 - "These data indicate that annual screening and treatment had a significant impact on infection status and morbidity and suggest that community therapy may be an effective approach to control schistosomiasis japonica in lake regions and marshlands in China. "
06/01/2016 - "Infection of schistosomiasis japonica may eventually lead to liver fibrosis, and no effective antifibrotic therapies are available but liver transplantation. "

12/01/2006 - "In the present study, we explored immunomodulation of egg granulomas in the liver in a pig model of schistosomiasis japonica. "
01/01/2000 - "TGF beta 1 plays an important role of immunomodulation in hepatic fibrosis formation caused by Schistosomiasis Japonica."