|1.||Coulson, Barbara S: 15 articles (10/2015 - 09/2002)|
|2.||Estes, Mary K: 14 articles (11/2014 - 01/2002)|
|3.||Holloway, Gavan: 11 articles (10/2015 - 11/2006)|
|4.||Glass, Roger I: 11 articles (07/2010 - 05/2002)|
|5.||Gentsch, Jon R: 10 articles (06/2015 - 05/2002)|
|6.||Crawford, Sue E: 9 articles (11/2014 - 02/2002)|
|7.||Arias, Carlos F: 8 articles (12/2015 - 03/2002)|
|8.||Blutt, Sarah E: 8 articles (01/2013 - 02/2002)|
|9.||Conner, Margaret E: 8 articles (01/2013 - 01/2002)|
|10.||Jiang, Baoming: 8 articles (07/2012 - 05/2002)|
|1.||Immunoglobulin A (IgA)IBA
04/01/1995 - "The purpose of this study was to determine the role of intestinal specific rotavirus IgA antibody in protection against diarrhoea due to rotavirus infection. "
01/01/2013 - "Rotavirus-specific intestinal IgA appears to be one of the principle effectors of long term protection against rotavirus infection. "
05/01/2000 - "Following primary rotavirus infection, IgA knockout mice cleared virus as effectively as IgA normal control mice. "
12/01/1995 - "Clearance of rotavirus infection in naive beta 2m knockout mice correlated with the development of intestinal rotavirus-specific immunoglobulin A. "
08/20/1995 - "It was also reported that protection against rotavirus infection in adult mice correlated with serum and stool rotavirus IgA titers. "
06/01/2000 - "An increasing number of observations, obtained from analyses of (i) natural rotavirus infections in infants and young children, (ii) experimental rotavirus infections in laboratory animals, and (iii) extensive rotavirus vaccine field trials performed in different populations of various parts of the world, appears to support the concept that serotype-specific antibodies to rotaviruses play an important role in protection against rotavirus-associated illnesses. "
01/01/1988 - "The mean percentage rotavirus inhibitory activity of cord sera in the infected and non-infected infants was 50.2 +/- 21.7 and 56.6 +/- 19.2 respectively (p greater than 0.05), suggesting that cord blood antibodies do not offer significant protection against neonatal rotavirus infection."
08/11/2014 - "Association of serum antibodies with protection against rotavirus infection and disease in South Indian children."
09/01/1990 - "The viral clearance was mediated by IELs that were both Thy1+ and CD8+. These data demonstrated that the clearance of chronic rotavirus infection in SCID mice can be mediated by immune CD8+ T lymphocytes and that this clearance can occur in the absence of virus-specific antibodies."
08/11/2014 - "The study supports a correlation of serum antibodies in reducing the risk of rotavirus infections, however the potential of serum antibody titer as a correlate of protection is not clear for children in lower income settings. "
11/01/2009 - "In brief, it was agreed that (1) even vaccines with lesser efficacy in developing countries, compared with industrialized countries, would still lead to substantial public health benefits and would be cost-effective in saving lives in Africa and Asia; (2) criteria, such as the WHO mortality strata and local epidemiology of rotavirus infection, would be appropriate measures for extrapolating the clinical data to other regions and countries; and (3) research toward understanding the programmatic limitations of rotavirus vaccine use may help develop strategies to improve vaccine uptake and overall impact."
01/01/2014 - "Whitehouse Station, New Jersey, USA) vaccines are effective for reducing the morbidity and mortality of rotavirus infection. "
02/01/2013 - "A combination of oral attenuated human rotavirus and intranasal 2/6VLP vaccines conferred immunogenicity, partial protection against a human rotavirus challenge and induced IFN-γ-producing T cells in the ileum of pigs with similar frequencies to human rotavirus infection. "
06/01/2012 - "We reviewed published studies on rotavirus infection and genotype distribution in India, as well as safety and immunogenicity studies of currently available vaccines. "
10/01/2011 - "The diversity of Rotavirus infection in the country is tremendous and since the safety, immunogenicity and efficacy data has not been collected for India, there is first a need to conduct studies to measure the extent of protection and cross-protection provided by the available vaccines for local strains, before venturing into Rotavirus vaccination program. "
07/01/2012 - "Our data suggest that rotavirus infection is susceptible to interference by other enteric viruses in the gut, which could result in reduced virus replication and contribute to lower immunogenicity and efficacy of oral rotavirus vaccines in low income countries."
10/03/1996 - "To provide a base line for assessing the efficacy of rotavirus vaccines, we evaluated the protection that is conferred by natural rotavirus infection. "
05/15/2002 - "We have reviewed data from a variety of studies in humans, including challenge experiments in adult volunteers, longitudinal studies of rotavirus infection in young children, and clinical trials of animal and animal-human reassortant rotavirus vaccines in infants. "
06/01/2015 - "Rotavirus vaccines have reduced greatly the number of children hospitalized due to rotavirus infection at the three sentinel hospitals; it is however unclear if the predominance of G2P and G9P genotypes is related to the vaccine introduction, or if this is attributable to normal genotype fluctuations. "
01/01/2014 - "Clinical and cost burden of rotavirus infection before and after introduction of rotavirus vaccines among commercially and Medicaid insured children in the United States."
09/01/2009 - "We aimed to investigate the effect of rotavirus on ion transport and the role of NSP4 in human-derived enterocytes, and to test the efficacy of human serum immunoglobulin in a model of rotavirus infection. "
01/01/2011 - "To determine the effectiveness and safety of oral immunoglobulin preparations for the prevention of rotavirus infection in hospitalized low birthweight infants (birthweight < 2500 g) The Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library), MEDLINE, EMBASE, CINAHL, biological Abstracts (BIOSIS), Science Citation Index for articles citing Barnes 1982 and the proceedings of the Pediatric Academic Societies from 1991 onwards were searched in July 2011. "
01/01/2011 - "Clinical trials that address the issue of oral immunoglobulin treatment of rotavirus infection are needed."
01/01/2003 - "Therefore, researchers should be encouraged to conduct well designed trials in neonates at risk for rotavirus infections using the newer preparations of anti-rotaviral immunoglobulins (colostrum, egg yolk immunoglobulins). "
01/01/2003 - "Current evidence from one randomised controlled trial does not support the routine use of oral immunoglobulin preparations for the prevention of rotavirus infection in low birth-weight infants. "
11/10/2011 - "VP8* antigen produced in tobacco transplastomic plants confers protection against bovine rotavirus infection in a suckling mouse model."
03/01/2014 - "The diagnosis of rotavirus infection was on the basis of a set of clinical, epidemiological data and the results of para-clinical and bacteriological studies and data of detection of rotavirus antigen strain. "
04/01/2003 - "Recent studies have shown that RT-PCR may detect more symptomatic cases of rotavirus infection than antigen detection methods. "
05/01/2014 - "Association between norovirus and rotavirus infection and histo-blood group antigen types in Vietnamese children."
01/01/2012 - "Using a mouse model of rotavirus infection, GRA reduced the duration of viral antigen shedding, and endpoint serum antibody titers were higher in GRA-treated animals. "
|7.||Immunoglobulin G (IgG)IBA
05/26/1997 - "Therefore, parenteral immunization with VP6 alone elicited large anti-rotavirus IgG responses but did not elicit protection against murine rotavirus infection in this model."
11/01/2009 - "Moreover, logistic regression analysis showed that resistance to rotavirus infection most closely correlated with higher prechallenge titers of IgG antibody to homotypic VP7 (G1) and VP4 (P1A). "
03/01/2007 - "Infants from the HSG who did not have rotavirus infections had significantly higher IgG GMTs in cord blood and serum samples at 6 months, than those HSG infants who had symptomatic/asymptomatic rotavirus infections (P < 0.05). "
05/17/2005 - "Serum IgG mediates mucosal immunity against rotavirus infection."
10/01/1993 - "Results provided evidence that circulating maternally derived IgG has an important role in protection of the intestinal mucosa against rotavirus infection during the first week of life. "
03/01/2009 - "Nevertheless, it appears that neutralizing antibodies have a role in protection against rotavirus infection and disease, but that other effectors, such as non-neutralizing antibodies and T cells, have important effector properties as well. "
06/01/1999 - "Immunization with VLPs may provide sufficient priming of the immune system to induce protective anamnestic heterotypic neutralizing antibody responses upon subsequent rotavirus infection. "
11/01/1998 - "Longitudinal monitoring suggested that serum neutralizing antibody responses were a more useful measure of severely symptomatic rotavirus infection than stool responses but that stool antibody responses may be a useful measure of rotavirus immunity."
01/01/1994 - "We have characterized the neutralizing antibody immune response to six human rotavirus serotypes (G1 to G4, G8, and G9) in Brazilian children with primary and secondary rotavirus infections and correlated the response with the G serotype of the infecting rotavirus strain. "
01/01/1994 - "Neutralizing antibody immune response in children with primary and secondary rotavirus infections."
01/01/1999 - "Protective efficacy of trypsin inhibitor on the the gut following rotavirus infection in malnourished infant mice."
10/01/2001 - "Soybean trypsin inhibitor confers protection against rotavirus infection in infant mice."
01/01/2005 - "Lipid composition and amino acid uptake during rotavirus infection and protection with trypsin inhibitor in malnourished infant mice."
01/01/2000 - "Influence of soybean trypsin inhibitor on small bowel enzyme activities during rotavirus infection in malnourished infant mice."
12/31/1999 - "To develop an orally delivered subunit vaccine for rotavirus infection, a trypsin cleavage product of VP4, recombinant VP8*, was expressed in Escherichia coli. "
05/19/2014 - "Immunized mice were challenged with EDIM rotavirus and protection against rotavirus infection, measured as viral shedding, was evaluated. "
11/01/2001 - "We examined the importance of T cell-independent B cell activity in the resolution of primary murine (EDIM) rotavirus infection in adult mice. "
12/20/1995 - "Following inoculation of one strain (JHD), rotavirus infection was resolved within days, but when later reinoculated with EDIM, these mice again shed rotavirus. "
11/01/1994 - "Using an adult mouse model to study active immunity against rotavirus infection, it was previously shown that oral immunization with some, but not all, animal rotavirus strains induced protection against subsequent infection following oral challenge with the murine rotavirus strain EDIM. "
12/20/1995 - "Finally, when microMT mice were depleted of CD8+ cells before the initial EDIM infection, gradual resolution of rotavirus shedding was still observed, suggesting a third effector mechanism was also involved in resolution of rotavirus infection in mice."
04/01/1999 - "[Trial of oral administration of Bifidobacterium breve for the prevention of rotavirus infections]."
12/01/2011 - "In a mouse model of rotavirus infection, effects of oral administration of CDCA on fecal rotavirus shedding were investigated. "
01/01/1985 - "Prevention of rotavirus infection by oral administration of cow colostrum containing antihumanrotavirus antibody."
01/01/1996 - "Oral administration of Rota colostrum seems to be an effective and safe means of preventing diarrhea caused by human rotavirus infection. "
10/01/1992 - "Oral administration of Rota colostrum seems to be an effective and safe means of preventing diarrhea caused by human rotavirus infection."
|2.||Day Care (Partial Hospitalization)
12/01/2006 - "This study gives, for the first time, an estimate of the incidence and the cost of rotavirus infection in day care centers in Lyon, France."
05/01/2010 - "Attendance at day care was a risk factor for asymptomatic rotavirus infection in children under age 5 years; living in a household with a baby that was still in diapers was a risk factor in older adults. "
01/01/2010 - "No significant association was found between rotavirus infection and nutritional status, HIV status and attendance of day care or school. "
12/06/2008 - "Repeated measures data for rotavirus infection in children within 14 day care centres (DCCs) in the Oxfordshire area, UK, are used to explore aspects of rotavirus transmission and immunity. "
08/01/2001 - "In a multivariant analysis age, family size, day care, breast-feeding and nationality were not predictive factors for enhanced risk to contract rotavirus infection. "
|3.||Fluid Therapy (Oral Rehydration Therapy)
01/01/2009 - "In the Netherlands about 3400 children are hospitalised each year for rehydration following rotavirus infection. "
01/01/2003 - "4) At least one of the following outcomes were reported: All cause mortality during hospital stay, mortality due to rotavirus infection during hospital stay, rotavirus infection, duration of diarrhoea, need for rehydration, duration of viral excretion, duration of infection control measures, length of hospital stay in days, recurrent diarrhoea or chronic diarrhoea. "
05/01/1980 - " 95% of the cases were judged successful on oral rehydration alone for gastrointestinal effects of rotavirus infection. "
07/01/2012 - "There was also no difference between the probiotic and placebo groups for any of the other secondary outcomes (ie, incidence of rotavirus infection, incidence of diarrhea, duration of diarrhea, incidence of recurrent diarrhea, incidence of chronic diarrhea, length of hospital stay in days, and frequency of need for rehydration). "
01/01/2008 - "Analysis of the questionnaires indicated that rotavirus infections were likely to be more severe than any other virus infection, and children from whom a viral pathogen was identified were more likely to require rehydration therapy."
03/01/2009 - "This study is the first to compare the histologic findings of rotavirus infection with acute cellular rejection in small bowel transplant biopsies. "
03/01/2009 - "As expected, the changes of acute cellular rejection were confined to the graft, in contrast to rotavirus infection, in which case native bowel often had more pronounced changes. "
03/01/2009 - "Rotavirus infection in small bowel transplant: a histologic comparison with acute cellular rejection."
05/01/1991 - "Four cases of nosocomial rotavirus infection were diagnosed (20% of patients), 3-34 days after graft. "
05/01/1991 - "We conducted a 24-month survey of hospital-acquired rotavirus infections in 20 renal transplant recipients who received their graft during 1988. "
|5.||Neonatal Intensive Care
02/01/2012 - "This study aims to describe clinical signs of rotavirus infections among neonates, with a particular focus on preterm infants, and to show the distribution of genotypes in a neonatal intensive care unit (NICU). "
12/01/2002 - "This report describes clinical signs of rotavirus infection (RVI) among neonates admitted to a neonatal intensive care unit (NICU), compares these signs between term and preterm neonates and assesses the seasonal distribution of RVI in the NICU with that of the community. "
12/01/2002 - "Clinical manifestations of rotavirus infection in the neonatal intensive care unit."
09/01/1983 - "Rotavirus infection in a neonatal intensive care nursery."
09/01/2009 - "We compared the RSV nosocomial infection rate in our neonatal intensive care unit before and after RSV prophylaxis, using nosocomial rotavirus infections as a comparator. "