Rodent Diseases

Diseases of rodents of the order RODENTIA. This term includes diseases of Sciuridae (squirrels), Geomyidae (gophers), Heteromyidae (pouched mice), Castoridae (beavers), Cricetidae (rats and mice), Muridae (Old World rats and mice), Erethizontidae (porcupines), and Caviidae (guinea pigs).

Also Known As:

Networked: 26 relevant articles (1 outcomes, 6 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Carcinoid Tumor (Carcinoid)
2.	Disease Progression
3.	Retinal Degeneration
4.	Inflammation (Inflammations)
5.	Acute Kidney Injury (Acute Renal Failure)

Experts

1.	Baba, Rina: 1 article (01/2022)
2.	Kimura, Haruhide: 1 article (01/2022)
3.	Maeda, Ryota: 1 article (01/2022)
4.	Matsuda, Satoru: 1 article (01/2022)
5.	Murakami, Koji: 1 article (01/2022)
6.	Nakatani, Atsushi: 1 article (01/2022)
7.	Yamamoto, Yukiko: 1 article (01/2022)
8.	Adachi, Masataka: 1 article (08/2021)
9.	Deng, Qinyuan: 1 article (08/2021)
10.	Hayata, Manabu: 1 article (08/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Rodent Diseases:

1.	telotristat ethylIBA 01/01/2018 - "They showed therapeutic efficacy in several rodent disease models, and telotristat ethyl is the first TPH inhibitor to be approved for the treatment of carcinoid syndrome. "
2.	Drinking WaterIBA 11/06/2023 - "Our study demonstrates that drinking water is a major environmental factor that can alter disease phenotypes and disease progression in rodent disease models."
3.	Methylnitrosourea (N-Methyl-N-nitrosourea)IBA 01/01/2013 - "To study such diseases, rodent models of N-methyl-N-nitrosourea (MNU)-induced retinal degeneration are widely used. "
4.	Sildenafil Citrate (Viagra)FDA Link 01/01/2022 - "For most indications, the rationale for administering prenatal sildenafil is based on limited, equivocal data from in vitro studies and rodent disease models. "
5.	evobrutinibIBA 09/10/2023 - "In conclusion, [11 C]evobrutinib was successfully synthesized by 11 C-carbonylation and based on our preliminary studies does not appear to be a promising BTK-targeted PET radiotracer in the rodent disease models studied herein."
6.	Proteins (Proteins, Gene)FDA Link 01/01/2020 - "The PEG-T3C proteins should prove useful for evaluating the potential therapeutic benefits of GM-CSF and long-acting GM-CSF proteins in rodent disease models." 11/21/2013 - "Described below is ABE/SILAM, a proteomic strategy that couples acyl-biotinyl exchange (ABE) purification of palmitoyl-proteins to whole animal stable isotope labeling (SILAM) to provide an accurate tracking of palmitoylation change within rodent disease models. " 02/01/2016 - "We will give an overview of the first proof-of-concept studies in rodent disease models and discuss challenges associated with developing antibodies against alpha-synuclein resulting from the distribution and structural characteristics of the protein. "
7.	alpha-SynucleinIBA 02/01/2016 - "We will give an overview of the first proof-of-concept studies in rodent disease models and discuss challenges associated with developing antibodies against alpha-synuclein resulting from the distribution and structural characteristics of the protein. "
8.	Sirolimus (Rapamycin)FDA Link 07/26/2023 - "Rapamycin modulates the mTOR pathway, preventing and reversing cardiac hypertrophy in rodent disease models. "
9.	Lactic Acid (Lactate)FDA LinkGeneric 10/01/1987 - "TNF/cachectin also increases plasma lactate, a change seen in both the human and rodent diseases. "
10.	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/01/2020 - "The PEG-T3C proteins should prove useful for evaluating the potential therapeutic benefits of GM-CSF and long-acting GM-CSF proteins in rodent disease models."

Therapies and Procedures

1.	Therapeutics 02/20/2023 - "While the studies reviewed here are still preclinical in cell lines and rodent disease models or have undergone initial clinical trials, potential therapeutics discussed here should not be used for non-approved conditions." 01/01/2021 - "Whereas the field continues to seek suitable rodent models for investigating potential therapeutics for these diseases, rodent models have still been used primarily for preclinical studies. " 01/01/2009 - "Here, clinical and experimental data are reviewed with respect to the effects of sex hormones or gender in the pathology or therapy of MS or its rodent disease models. "
2.	Transplantation 02/01/2011 - "However, in a rodent disease model, the transplantation of differentiated cells derived from iPS cells ameliorated their symptoms. "
3.	Anesthesia 02/01/2012 - "However, ppTMS protocols in rodent disease models, where mechanistic insight into the ppTMS physiology and into disease processes may be obtained, have been limited due to the requirement for anesthesia and needle electromyography. "