|1.||Guan, Min-Xin: 13 articles (07/2015 - 01/2004)|
|2.||Yang, Li: 7 articles (05/2010 - 04/2006)|
|3.||Zhu, Yi: 6 articles (05/2010 - 04/2006)|
|4.||Tang, Xiaowen: 4 articles (07/2015 - 04/2006)|
|5.||Lu, Jianxin: 4 articles (05/2010 - 04/2006)|
|6.||Han, Dongyi: 4 articles (09/2008 - 10/2004)|
|7.||Yuan, Huijun: 4 articles (09/2008 - 10/2004)|
|8.||Ding, Yu: 3 articles (01/2016 - 08/2013)|
|9.||Zheng, Jing: 3 articles (07/2015 - 05/2010)|
|10.||Liu, Xin: 3 articles (03/2015 - 10/2007)|
|1.||Hearing Loss (Hearing Impairment)
09/01/2011 - "In the present study, we have performed the systematic mutation screening of the COI/tRNA(Ser(UCN)) genes in 250 unrelated Polish subjects with hearing impairment. "
12/01/2015 - "Mitochondrial COI/tRNASer(UCN) G7444A mutation may be associated with aminoglycoside-induced and non-syndromic hearing impairment."
07/01/2015 - "These data further support that the mitochondrial tRNA(Ser(UCN)) gene is the hot spot for mutations associated with hearing loss. "
07/01/2015 - "In this report, we have investigated the prevalence and spectrum of mitochondrial tRNA(Ser(UCN)) mutations in a large cohort of 2651 Han Chinese subjects with hearing loss. "
07/01/2015 - "Mitochondrial tRNA(Ser(UCN)) variants in 2651 Han Chinese subjects with hearing loss."
|2.||Deafness (Deaf Mutism)
04/01/2009 - "A deafness-associated G7444A mutation in the precursor of tRNA(Ser(UCN)) gene was identified in 8/500 (1.6%) unrelated blood donors. "
02/01/2006 - "Our results indicate that screening for the A1555G mutation is recommended among all Brazilian deaf patients, while testing for mutations in the tRNASer(UCN) gene should be considered only when other frequent deafness-causing mutations have been excluded or in the presence of a maternal transmission pattern."
03/11/2005 - "The deafness-associated A7445G mutation in the precursor of mitochondrial tRNA(Ser(UCN)) has been identified in several pedigrees from different ethnic backgrounds. "
05/07/2004 - "Thus, it may play a role in the fidelity in mitochondrial translation and pathogenesis of deafness-associated mutations in the mitochondrial tRNA(Ser(UCN))."
01/01/2004 - "Biochemical characterization of the mitochondrial tRNASer(UCN) T7511C mutation associated with nonsyndromic deafness."
|3.||Mitochondrial Myopathies (Mitochondrial Myopathy)
09/01/2006 - "A novel mutation in the mitochondrial tRNA(Ser(AGY)) gene associated with mitochondrial myopathy, encephalopathy, and complex I deficiency."
10/01/2005 - "Late-onset mitochondrial myopathy with dystrophic changes due to a G7497A mutation in the mitochondrial tRNA(Ser(UCN)) gene."
07/01/2004 - "Sporadic mitochondrial myopathy due to a new mutation in the mitochondrial tRNASer(UCN) gene."
10/01/1998 - "Progressive myoclonus epilepsy and mitochondrial myopathy associated with mutations in the tRNA(Ser(UCN)) gene."
10/01/2005 - "Mitochondrial myopathy and high level of mutated mtDNA might be a characteristic of the G7497A tRNA(Ser(UCN)) mutation."
|4.||Sensorineural Hearing Loss
09/01/2008 - "Mutations at position 7445 in the precursor of mitochondrial tRNA(Ser(UCN)) gene in three maternal Chinese pedigrees with sensorineural hearing loss."
01/01/2008 - "Haplogroup analysis supports a pathogenic role for the 7510T>C mutation of mitochondrial tRNA(Ser(UCN)) in sensorineural hearing loss."
11/01/2007 - "Among 1350 families with non-syndromic sensorineural hearing loss collected through a French collaborative network, we selected 29 large families with a clear maternal lineage and screened them for known mtDNA mutations in 12S rRNA, tRNASer(UCN) and tRNALeu(UUR) genes. "
01/01/2011 - "Using denaturing high-performance liquid chromatography combined with direct sequencing and cloning-sequencing, Japanese patients with prelingual (N = 54) or postlingual (N = 80) sensorineural hearing loss not having pathogenic mutations of m.1555A > G and m.3243A > G nor GJB2 were subjected to mutational analysis of mtDNA genes (12S rRNA, tRNALeu(UUR), tRNASer(UCN), tRNALys, tRNAHis, tRNASer(AGY), and tRNAGlu). "
|5.||Muscular Diseases (Myopathy)
10/01/1998 - "A novel G7497A mutation is found in two families, both of which present with progressive myopathy, ragged-red fibers, lactic acidosis, and deficiency of respiratory chain complexes I and IV. This mutation presumably affects the tertiary tRNA(Ser(UCN)) dihydrouridine interaction. "
10/01/2008 - "We describe the clinical, biochemical and molecular findings in a family with progressive myopathy, deafness and diabetes and striking respiratory chain abnormalities due to a well-characterized heteroplasmic mt-tRNA mutation in the mt-tRNA(Ser(UCN)) (MTTS1) gene. "
08/01/2012 - "Mutations in the mitochondrial tRNA Ser(AGY) gene are associated with deafness, retinal degeneration, myopathy and epilepsy."
|1.||12S ribosomal RNA
|2.||Leu Transfer RNA
|3.||Lys Transfer RNA
|4.||Mitochondrial DNA (mtDNA)
|5.||Transfer RNA (tRNA)
|6.||Mitochondrial Proteins (Mitochondrial Protein)
|7.||His Transfer RNA
|8.||DNA (Deoxyribonucleic Acid)
|10.||Initiator Codon (Start Codon)
|1.||Heterologous Transplantation (Xenotransplantation)