|1.||Akira, Shizuo: 11 articles (06/2013 - 09/2003)|
|2.||Seya, Tsukasa: 10 articles (02/2014 - 05/2002)|
|3.||Matsumoto, Misako: 10 articles (02/2014 - 05/2002)|
|4.||Williams, Bryan R G: 8 articles (10/2012 - 01/2003)|
|5.||Sen, Ganes C: 8 articles (01/2011 - 10/2003)|
|6.||Imaizumi, Tadaatsu: 7 articles (02/2013 - 08/2004)|
|7.||Patton, John T: 6 articles (05/2015 - 12/2006)|
|8.||Gale, Michael: 6 articles (01/2015 - 04/2002)|
|9.||Weber, Friedemann: 6 articles (11/2013 - 01/2004)|
|10.||Cui, Zhengrong: 6 articles (06/2013 - 06/2006)|
04/01/2013 - "In this study we investigated human mast cell response to double-stranded RNA and viral infection. "
05/01/2012 - "In this study, we discovered that down-regulation of TICAM1, but not other components in this signaling pathway, occurred in a natural process of TLR3 activation induced by double-stranded RNA or human rhinovirus (RV) infection in airway epithelial cells and various other cell types. "
09/01/2011 - "A mixed virus infection in a strain of the endophytic and entomopathogenic fungus Tolypocladium cylindrosporum was deduced from a study of the transmission to conidia of several double-stranded RNA (dsRNA) elements. "
10/01/2005 - "Herein, we present a comprehensive study on the chemokine production by microglia in response to double-stranded RNA (dsRNA), a conserved molecular pattern of virus infection. "
05/01/2004 - "For example, in vitro studies reveal that the TLR3 ligand is a double-stranded RNA (dsRNA), a product of viral infections. "
01/15/2009 - "Attenuated expression of A20 markedly increases the efficacy of double-stranded RNA-activated dendritic cells as an anti-cancer vaccine."
01/01/2015 - "Reovirus is one such naturally occurring double-stranded RNA virus that exploits altered signaling pathways (including Ras) in a myriad of cancers. "
06/03/2013 - "Double-stranded RNA (dsRNA) has multiple antitumor mechanisms that may be used to control tumor growth. "
01/01/2012 - "Compared with primary tumor cells, metastatic tumor cells were highly sensitive to TLR3-mediated apoptosis after double-stranded RNA treatment. "
03/01/2011 - "Adjuvant treatment with double-stranded RNA (dsRNA) was associated with a significant decrease in the risk of metastatic relapse in TLR3 positive but not in TLR3-negative breast cancers. "
|3.||Breast Neoplasms (Breast Cancer)
03/01/2011 - "TLR3 as a biomarker for the therapeutic efficacy of double-stranded RNA in breast cancer."
07/01/2006 - "Chemically synthesized double stranded RNA (dsRNA) targeting HYAL1 was transfected into human breast cancer cell lines MDA-MB-231, MDA-MB-453S, ZR-75 and ZR-75-30 using SiPORT lipid. "
01/01/2013 - "In this study, we show that RA is able to induce the intrinsic ability of breast cancer cells to recognize double-stranded RNA (dsRNA) through the upregulation of Toll-like receptor 3 (TLR3) expression. "
01/01/2012 - "Double-stranded RNA-dependent protein kinase regulates the motility of breast cancer cells."
06/24/2008 - "Double stranded RNA (dsRNA) targeting the livin gene was chemically synthesized in vitro and transfected into human breast cancer cells of the line ZR-75-30 mediated by lipofectamine 2000. "
11/01/2010 - "The parasite cultures treated with co-addition of PfeIF4A and PfeIF4E double stranded RNA showed ∼67% growth inhibition suggesting that inhibition of two components of the same pathway is more effective for inhibiting the proliferation of the malaria parasite Plasmodium falciparum. "
09/01/2002 - "In this study, we report the results of RNAi by double-stranded RNA of cysteine protease genes (falcipain-1 and -2) in the malaria parasite, Plasmodium falciparum. "
04/03/2009 - "Inhibition of Plasmodium falciparum proliferation in vitro by double-stranded RNA directed against malaria histone deacetylase."
02/01/2002 - "Erythrocyte-infecting stages of the malaria parasite Plasmodium falciparum were treated with double-stranded RNA (dsRNA) encoding a segment of the gene encoding dihydroorotate dehydrogenase (DHODH). "
10/01/2010 - "Chitosan/double-stranded RNA nanoparticle-mediated RNA interference to silence chitin synthase genes through larval feeding in the African malaria mosquito (Anopheles gambiae)."
05/01/1988 - "Transfection studies on DNA obtained from 16 multiple sclerosis (MS) and 13 non-MS brain tissues suggested that 3/16 (19%) MS and 3/13 (23%) non-MS samples contained contaminating measles virus double-stranded RNA, and that 6/16 (38%) MS and 0/13 non-MS samples contained DNA transcripts of measles genes. "
12/01/1989 - "Cultures of diploid human fibroblasts and these tumor cells stimulated with interleukin (IL) 1 or double-stranded RNA [poly(rI).poly(rC)], or infected with viruses (measles or rubella viruses) were found to produce chemotactic activity for both monocytes and granulocytes. "
07/01/1985 - "Of a series of carbocyclic analogs of adenosine, in which the ribose moiety was replaced by a cyclopentenyl ring, neplanocin A, or (-)-9-[trans-2, trans-3-dihydroxy-4-(hydroxymethyl)cyclopent-4-enyl]adenine proved particularly effective in inhibiting the multiplication of DNA viruses (i.e., vaccinia), (-)RNA viruses (i.e., parainfluenza, measles, and vesicular stomatitis), and double-stranded RNA viruses (i.e., reo) in vitro in cell culture. "
|3.||Protein Kinases (Protein Kinase)
|4.||Small Interfering RNA (siRNA)
|6.||Peptide Initiation Factors (Initiation Factor)
|10.||Caspase 3 (Caspase-3)