|1.||Brownlee, George G: 8 articles (05/2010 - 07/2002)|
|2.||Fodor, Ervin: 6 articles (11/2015 - 04/2003)|
|3.||Canard, Bruno: 5 articles (09/2014 - 03/2006)|
|4.||Severinov, Konstantin: 4 articles (12/2015 - 10/2006)|
|5.||White, Robert J: 4 articles (05/2014 - 01/2005)|
|6.||Jin, Ding Jun: 4 articles (03/2012 - 06/2003)|
|7.||Deng, Tao: 4 articles (07/2009 - 04/2003)|
|8.||Cusack, Stephen: 3 articles (11/2015 - 01/2007)|
|9.||Tan, Ming: 3 articles (01/2015 - 12/2006)|
|10.||Botta, Maurizio: 3 articles (01/2014 - 10/2013)|
|1.||Human Influenza (Influenza)
01/01/2009 - "Here we extend our studies of the influenza RNA polymerase to that of influenza strains A/HongKong/156/97 (H5N1) and A/Vietnam/1194/04 (H5N1). "
03/01/2006 - "These results are discussed in relation to the previous studies and a new model for vRNA promoter binding to the influenza RNA polymerase is presented."
09/18/2015 - "Recombinant WSN carrying the S377G NP is resistant to PPQ in anti-influenza and RNA polymerase assays. "
01/01/2014 - "A high-throughput molecular docking approach was successfully applied for the selection of potential inhibitors of the Influenza RNA-polymerase which act by targeting the PA-PB1 protein-protein interaction. "
10/15/2013 - "The identification of a novel hit compound inhibitor of the protein-protein interaction between the influenza RNA-polymerase PA and PB1 subunits has been accomplished by means of high-throughput screening. "
08/25/1995 - "In the present study, we analyzed the differential expression of the two NF1 mRNAs in 16 cases of human astrocytic tumors and in surrounding normal tissues by the RNA-polymerase chain reaction. "
05/01/2014 - "Here we discuss MYC's influence on transcription by these "odd" RNA polymerases and the physiological impact of this regulation is evaluated with relevance to cancer development and treatment."
05/01/2013 - "However, recent technological advances have led to a 'quantum leap' in our comprehension of the structure and function of the core RNA polymerase components, how they are dysregulated in a broad range of cancers and how they may be targeted for 'transcription therapy'."
05/01/2013 - "Dysregulation of the basal RNA polymerase transcription apparatus in cancer."
10/01/2012 - "To address this challenge, we developed a novel sensing platform using aptamer and RNA polymerase-based amplification for the detection of cancer cells. "
01/01/1992 - "Kinetic study of alterations in the host RNA polymerase and protein synthesis during phage Xp 10 infection."
06/01/1987 - "Results of these studies indicated that RNA polymerase subunit genes are transcribed early in infection and are distributed within the highly conserved central portion of the poxvirus genome in HindIII fragments E, J, H, D, and A."
06/01/1969 - "More recent studies on the mechanism of this inactivation have been made in this(2) and other laboratories.(3, 4) In this communication, we report the observation of a transient stimulation of RNA polymerase activity when measurement is made immediately after infection and when cells are ruptured by a gentle lysis procedure. "
02/15/2015 - "Serial HCV antibody tests and RNA polymerase chain reaction assays revealed acute HCV infection and genotyping showed HCV genotype 2a/2c. "
02/01/2015 - "HCV RNA polymerase is a key target for the development of directly acting agents to cure HCV infections, which necessitates a thorough understanding of the functional roles of the various structural features of the RdRp. "
07/19/2005 - "We used a series of vesicular stomatitis virus clones harboring single amino acid substitutions in the RNA polymerase to demonstrate that changes inducing enhanced fidelity paid a fitness cost, but that there was no positive correlation between mutation an adaptation rates. "
06/01/2005 - "The vesicular stomatitis virus (VSV) RNA polymerase synthesizes viral mRNAs with 5'-cap structures methylated at the guanine-N7 and 2'-O-adenosine positions (7mGpppA(m)). "
05/01/2001 - "The matrix (M) protein of vesicular stomatitis virus (VSV) is a potent inhibitor in vivo of transcription by all three host RNA polymerases (RNAP). "
10/01/1998 - "Effect of vesicular stomatitis virus matrix protein on transcription directed by host RNA polymerases I, II, and III."
02/17/1998 - "RNA polymerase of vesicular stomatitis virus specifically associates with translation elongation factor-1 alphabetagamma for its activity."
|5.||Sarcoma (Soft Tissue Sarcoma)
05/30/1980 - "Binding of Escherichia coli RNA polymerase to a specific site located near the 3'-end of the avaian sarcoma virus genome."
09/01/1967 - "[Homopolymerase properties of RNA-polymerase from M-1 sarcoma]."
04/01/1990 - "The enzyme purified to homogeneity was shown to be made up of two subunits with molecular masses of 97 +/- 4 and 61 +/- 3 kDa. A comparison of enzymatic properties of recombinant transcriptase to those of the enzyme isolated from the RSV (Rauss sarcoma) virus demonstrated that in the preparations under study the recombinant reverse transcriptase exists in a subunit form, alpha beta, and may acquire a relatively stable configuration, alpha 2."
09/01/1986 - "Against a background of considerable stimulation of the incorporation of precursors in RNA under the influence of rat liver HRC (2.64 times), sarcoma HRC increased RNA synthesis in the system by 31.7% only to determine the RNA-polymerase activity of the nuclei. "
12/01/1989 - "A random transcription system was used to analyze RNA chain-elongation complexes with RNA polymerases I and II from mouse ascites sarcoma cells. "
|1.||DNA (Deoxyribonucleic Acid)
|3.||Proteins (Proteins, Gene)
|4.||Messenger RNA (mRNA)
|5.||Telomerase (Telomerase Reverse Transcriptase)
|6.||DNA-Directed DNA Polymerase (Polymerases, DNA)
|7.||1- (3- C- ethynylribopentofuranosyl)cytosine
|9.||Deoxyribonuclease I (Nickase)
|10.||Adenosine Triphosphate (ATP)
|2.||Highly Active Antiretroviral Therapy (HAART)
|4.||Transplantation (Transplant Recipients)