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RNA Polymerase I (Polymerase I, RNA)

A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. The enzyme functions in the nucleolar structure and transcribes DNA into RNA. It has different requirements for cations and salts than RNA polymerase II and III and is not inhibited by alpha-amanitin.
Also Known As:
Polymerase I, RNA; RNA Polymerase A; DNA Dependent RNA Polymerase I; Polymerase A, RNA; DNA-Dependent RNA Polymerase I
Networked: 229 relevant articles (6 outcomes, 17 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Hannan, Ross D: 16 articles (01/2022 - 02/2011)
2. Pearson, Richard B: 12 articles (11/2021 - 07/2012)
3. Hannan, Katherine M: 9 articles (01/2022 - 02/2015)
4. Sanij, Elaine: 9 articles (11/2021 - 02/2011)
5. Drygin, Denis: 8 articles (01/2022 - 01/2010)
6. Iben, Sebastian: 7 articles (11/2021 - 09/2008)
7. Poortinga, Gretchen: 6 articles (11/2020 - 07/2012)
8. Hein, Nadine: 5 articles (01/2022 - 07/2012)
9. Cameron, Donald P: 5 articles (01/2020 - 11/2016)
10. Scharffetter-Kochanek, Karin: 5 articles (01/2018 - 09/2008)

Related Diseases

1. Neoplasms (Cancer)
2. Systemic Scleroderma (Systemic Sclerosis)
3. Carcinogenesis
4. Leukemia
5. Neuroblastoma

Related Drugs and Biologics

1. CX 5461
2. Ribosomal DNA (rDNA)
3. Antibodies
4. Androgen Receptors (Androgen Receptor)
5. Poly(ADP-ribose) Polymerase Inhibitors
6. Dactinomycin (Actinomycin)
7. Proteins (Proteins, Gene)
8. Enzymes
9. RNA Polymerase II (RNA Polymerase B)
10. Autoantibodies

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)