|1.||Demicheli, V: 7 articles (01/2006 - 01/2000)|
|2.||Rivetti, D: 7 articles (01/2006 - 01/2000)|
|3.||De Clercq, Erik: 6 articles (10/2015 - 05/2003)|
|4.||Burtseva, E I: 6 articles (06/2012 - 03/2007)|
|5.||Shevchenko, E S: 5 articles (06/2012 - 03/2007)|
|6.||L'vov, D K: 5 articles (01/2012 - 07/2005)|
|7.||Fediakina, I T: 5 articles (01/2012 - 07/2005)|
|8.||Hayden, F G: 5 articles (08/2002 - 03/2000)|
|9.||Shchelkanov, M Iu: 4 articles (03/2014 - 03/2006)|
|10.||Chou, James J: 4 articles (06/2013 - 03/2010)|
|1.||Human Influenza (Influenza)
09/01/1990 - "These findings indicate that low-dose rimantadine is well tolerated and highly effective for the prevention of influenza A illness in healthy adults."
10/14/1988 - "A gas chromatographic-mass spectrometric procedure has been developed for the quantitation in plasma and urine of the enantiomers of rimantadine, an antiviral drug effective against type A influenza. "
10/01/1987 - "A GC-MS procedure has been developed for the quantitation in plasma and urine of rimantadine, an antiviral drug effective against type A influenza. "
05/01/1978 - "The therapeutic and prophylactic efficacy of rimantadine in familial foci during influenza A1 outbreaks was studied. "
05/01/1969 - "The therapeutic efficacy of rimantadine HC1 in a naturally occurring influenza A2 outbreak."
12/01/2004 - "Maximum synergy against A/New Caledonia/20/99 (H1N1) virus infection was observed with <2.5 microM rimantadine paired with low concentrations of NA inhibitors. "
10/01/2003 - "Thus, rimantadine should be the preferred agent in this class for the prevention of influenza A virus infection and should be made available in Canada."
10/01/2003 - "A case for rimantadine to be marketed in Canada for prophylaxis of influenza A virus infection."
05/01/1999 - "Sensitivity to rimantadine is higher in a variant obtained similarly by cell culture infection with rimantadine-resistant FPV. "
04/01/1997 - "Combined protective effect of an immunostimulatory bacterial preparation and rimantadine in experimental influenza A virus infection."
01/01/2014 - " treatment, rimantadine was beneficial in abating fever on day three of treatment in children: one selected study with low risk of bias, moderate evidence quality and 69 participants (RR 0.36; 95% CI 0.14 to 0.91). "
08/01/1987 - "Children receiving rimantadine showed significantly greater reduction in fever and improvement in daily scores for symptoms and severity of illness during the first three days. "
09/01/1991 - "In a family-based study, rimantadine treatment for 10 days (24 children and adults) was associated with significant decreases in the number of days to a 50% reduction in symptoms (mean difference, 2.5 days), days of fever (1.6 days), and days of restricted activity (1.5 days) compared with the results obtained with placebo-treated patients (32 children and adults). "
01/06/2000 - "73-1.29), and oral rimantadine significantly shortened duration of fever (by 1.27 days - 95%CI: 0.77-1.77). "
01/01/1994 - "Remantadine application decreased fever and complication rates and reduced the duration of intoxication symptoms and the diseases as a whole. "
|4.||Influenza in Birds (Avian Flu)
05/01/2010 - "TZV was also effective against a rimantadine-resistant influenza virus strain and against avian influenza A virus H5N1 strains. "
09/01/2005 - "The fear that avian influenza could be a precursor to the next pandemic is real and inevitable, given the extremely high case-fatality ratio among confirmed cases and that genetic sequencing of influenza A (H5N1) viruses from human cases in Thailand and Vietnam show resistance to the antiviral medication amantadine and rimantadine. "
03/01/1985 - "Virion deproteinization and viral RNA transport to the isolated cell nuclei have been studied in the presence of rimantadine with rimantadine-sensitive influenza viruses fowl plague (H7N7), A/Krasnodar/101/59 (H2N2) and rimantadine-resistant influenza strains (WSN/H1N1 and A/Krasnodar/101/59-R). "
03/01/2006 - "Commercial drugs, such as rimantadine, amantadine, rivabirine, and arbidole, are effective in suppressing the in vitro reproduction of highly pathogenic avian influenza A/H5N1 viruses. "
07/01/2005 - "The antiviral agents rimantadine, ribavirine, and tamiflu were tested for the effects on the reproduction of avian influenza virus A/H5 in in vitro experiments. "
09/01/1987 - "In the groups of mice infected with remantadine-resistant strain of influenza virus and Staphylococcus remantadine showed no significant effect on these parameters: the lethality decreased by 6.7% only, the average survival time increased only by 0.33 days, the incidence of pneumonia decreased by 9%, its intensity by 19.2%; influenza virus titres in the lung tissue did not change significantly."
09/01/1987 - "When the drug was injected to the mice infected with remantadine-sensitive strain of influenza A virus and Staphylococcus the lethality decreased from 93.3% to 26.7%, the survival time increased from 3.8 to 10.1 days, the incidence of pneumonia decreased from 85.7% to 48.7%, the average intensity of pneumonia decreased from 66.4% to 9.9%, and virus titres in the lungs decreased by 3.5-4.0 lg EID50 (p less than 0.05). "
01/01/1980 - "[Prevention of pneumonia in influenza A by means of a new anti-influenza drug rimantadine]."
11/01/2004 - "Six untreated patients (18%) developed pneumonia, whereas 1 (13%) of 8 patients treated with rimantadine and 0 of 9 treated with oseltamivir developed pneumonia. "
06/01/2001 - "Antiviral treatment was begun 4 +/- 3 days from initiation of symptoms in patients with pneumonia and consisted of oseltamivir (35.2%), rimantadine (5.8%), or a combination of both (17.6%). "
|2.||Antiviral Agents (Antivirals)
|7.||Ion Channels (Ion Channel)
|9.||Influenza Vaccines (FluMist)
|2.||Drug Therapy (Chemotherapy)
|5.||Home Nursing (Nursing, Home)