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Ribonucleoside Diphosphate Reductase

An enzyme of the oxidoreductase class that catalyzes the formation of 2'-deoxyribonucleotides from the corresponding ribonucleotides using NADPH as the ultimate electron donor. The deoxyribonucleoside diphosphates are used in DNA synthesis. (From Dorland, 27th ed) EC 1.17.4.1.
Also Known As:
UDP Reductase; Diphosphate Reductase, Ribonucleoside; Reductase, Ribonucleoside Diphosphate; Reductase, UDP; 2'-Deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase
Networked: 19 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Gazvani, Rafet: 1 article (01/2007)
2. Cash, Phillip: 1 article (01/2007)
3. Simpson, William G: 1 article (01/2007)
4. Tattum, Jenny: 1 article (01/2007)
5. Klonisch, Thomas: 1 article (01/2007)
6. Hombach-Klonisch, Sabine: 1 article (01/2007)
7. Fowler, Paul A: 1 article (01/2007)
8. Miller, Iain: 1 article (01/2007)
9. Lea, Richard G: 1 article (01/2007)
10. Bhattacharya, Siladitya: 1 article (01/2007)

Related Diseases

1. Infection
2. Neoplasms (Cancer)
3. Hepatocellular Carcinoma (Hepatoma)
4. Thyroid Neoplasms (Thyroid Cancer)
5. Sarcoma 180

Related Drugs and Biologics

1. Ligases
2. triphosphoric acid (triphosphate)
3. Hydroxyurea (Hydrea)
4. Enzymes
5. DNA (Deoxyribonucleic Acid)
6. Adenosine Deaminase
7. deoxyguanosine triphosphate (dGTP)
8. Peroxiredoxins
9. Molecular Chaperones (Chaperone, Molecular)
10. Platinum Compounds (Compounds, Platinum)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)