Riboflavin Synthase

An enzyme that catalyzes the formation of riboflavin from two molecules of 6,7-dimethyl-8-ribityllumazine, utilizing a four-carbon fragment from one molecule which is transferred to the second molecule. EC 2.5.1.9.

Also Known As:

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Bacher, Adelbert: 2 articles (08/2009 - 09/2007)
2.	Cushman, Mark: 2 articles (08/2009 - 09/2007)
3.	Fischer, Markus: 2 articles (08/2009 - 09/2007)
4.	Illarionov, Boris: 2 articles (08/2009 - 09/2007)
5.	Bonomi, Hernán Ruy: 1 article (01/2019)
6.	Carrica, Mariela Del Carmen: 1 article (01/2019)
7.	Cerutti, María Laura: 1 article (01/2019)
8.	Goldbaum, Fernando Alberto: 1 article (01/2019)
9.	Klinke, Sebastián: 1 article (01/2019)
10.	López Romero, Sandra: 1 article (01/2019)

Related Diseases

1.	Mucormycosis 01/01/2023 - "The present study aimed at compositional profiling of EO and molecular docking of EO's bioactive compound 1,8 cineole against fungal enzymes involved in the riboflavin synthesis pathway, namely riboflavin synthase (RS), riboflavin biosynthesis protein RibD domain-containing protein (RibD), and 3,4-dihydroxy-2-butanone 4-phosphate synthase (DBPS) as apposite sites for drug designing against aspergillosis and mucormycosis, and in vitro confirmation. "
2.	Aspergillosis 01/01/2023 - "The present study aimed at compositional profiling of EO and molecular docking of EO's bioactive compound 1,8 cineole against fungal enzymes involved in the riboflavin synthesis pathway, namely riboflavin synthase (RS), riboflavin biosynthesis protein RibD domain-containing protein (RibD), and 3,4-dihydroxy-2-butanone 4-phosphate synthase (DBPS) as apposite sites for drug designing against aspergillosis and mucormycosis, and in vitro confirmation. "
3.	Tuberculosis (Tuberculoses) 09/14/2007 - "tuberculosis riboflavin synthase (Ki 2.5 microM)." 08/07/2009 - "tuberculosis riboflavin synthase and moderate antibiotic activity against both M. "
4.	Colorectal Neoplasms (Colorectal Cancer) 12/19/2022 - "Therapeutic Target Identification and Inhibitor Screening against Riboflavin Synthase of Colorectal Cancer Associated Fusobacterium nucleatum."
5.	Endocarditis 08/01/2004 - "koehlerae was identified in the valvular tissue of an endocarditis patient by DNA sequencing of the PCR products of two Bartonella genes: the genes for citrate synthase (gltA) and riboflavin synthase (ribC). "

Related Drugs and Biologics

1.	Riboflavin (Vitamin B2)
2.	Proteins (Proteins, Gene)
3.	Enzymes
4.	Eucalyptol
5.	3,4-dihydroxy-2-butanone
6.	discoidin-binding polysaccharide
7.	DNA (Deoxyribonucleic Acid)
8.	Citrate (si)-Synthase (Synthase, Citrate)
9.	Anti-Bacterial Agents (Antibiotics)