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Rhodopsin (Visual Purple)

A purplish-red, light-sensitive pigment found in RETINAL ROD CELLS of most vertebrates. It is a complex consisting of a molecule of ROD OPSIN and a molecule of 11-cis retinal (RETINALDEHYDE). Rhodopsin exhibits peak absorption wavelength at about 500 nm.
Also Known As:
Visual Purple; Rhodopsins
Networked: 1014 relevant articles (22 outcomes, 66 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Lewin, Alfred S: 16 articles (10/2021 - 08/2005)
2. Moritz, Orson L: 16 articles (11/2019 - 01/2006)
3. Garriga, Pere: 15 articles (01/2022 - 02/2003)
4. Gross, Alecia K: 14 articles (01/2021 - 02/2003)
5. Cheetham, Michael E: 13 articles (01/2020 - 07/2002)
6. Lin, Jonathan H: 12 articles (11/2021 - 11/2007)
7. Kondo, Mineo: 11 articles (06/2021 - 09/2009)
8. Gorbatyuk, Marina S: 11 articles (11/2019 - 03/2010)
9. LaVail, Matthew M: 11 articles (10/2019 - 07/2003)
10. Tam, Beatrice M: 11 articles (01/2019 - 01/2006)

Related Diseases

1. Retinal Degeneration
2. Retinitis Pigmentosa (Pigmentary Retinopathy)
3. Photophobia (Light Sensitivity)
4. Retinal Diseases
5. Ganglion Cysts (Ganglion)
02/15/2003 - "During the first postnatal week, these rhodopsin-positive cells are eliminated from the ganglion cell layer, but such neurons remain in the inner nuclear layer well into the first postnatal month. "
11/01/2007 - "However, unlike lamprey rhodopsin-containing cells, lamprey parapinopsin-containing cells connected with each other in a wide area of dorsal and peripheral portions and made direct contact with ganglion cells, mainly in the peripheral portion. "
12/01/1996 - "The simulation showed that coupling in the AII network can: (1) improve the signal/noise ratio in the AII network; (2) improve the signal/noise ratio for a single rhodopsin isomerization striking in the periphery of the ganglion cell receptive field center, and therefore in most ganglion cells responding to a single isomerization; (3) expand the AII and ganglion cells' receptive field center; and (4) expand the "correlation field". "
02/01/1979 - "P is considerably larger (about 2.5-fold) for the same fraction bleached in experiments at 14 degrees C as compared to experiments at 9 degrees C.6. A comparison with previously obtained corresponding values for dark-adaptation after small bleaches at the ganglion cell level shows a close agreement between the time constants for the dark-adaptation curve, its range and the dependence of threshold on the fraction of rhodopsin bleached."
10/01/1970 - "For example, after flash adaptation that bleached 80% of the rhodopsin, neither ganglion cell nor b-wave activity could be elicited for 10-15 min. Following this unresponsive period, thresholds fell rapidly; by 20 min after the flash, sensitivity was within 3 log units of the dark-adapted level. "

Related Drugs and Biologics

1. Arrestin
2. Proteins (Proteins, Gene)
3. Retinaldehyde (Retinal)
4. Zinc
5. Tubulin
6. Complementary DNA (cDNA)
7. Ion Channels (Ion Channel)
8. Catenins
9. Chloride Channels (Chloride Channel)
10. G-Protein-Coupled Receptors (Receptors, G Protein Coupled)

Related Therapies and Procedures

1. Therapeutics
2. Laser Therapy (Surgery, Laser)
3. Injections
4. Telescopes
5. Intravitreal Injections