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Vasomotor Rhinitis

A form of non-allergic rhinitis that is characterized by nasal congestion and posterior pharyngeal drainage.
Also Known As:
Rhinitis, Vasomotor; Rhinitides, Vasomotor; Vasomotor Rhinitides
Networked: 297 relevant articles (20 outcomes, 38 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Allergic Rhinitis
2. Nasal Polyps (Nasal Polyp)
3. Eosinophilia
4. Rhinorrhea
5. Ganglion Cysts (Ganglion)

Experts

1. Bernstein, Jonathan A: 7 articles (01/2017 - 10/2007)
2. Kaliner, Michael A: 5 articles (05/2013 - 04/2005)
3. Lieberman, Phil: 4 articles (03/2014 - 04/2005)
4. Settipane, Russell A: 3 articles (05/2013 - 03/2003)
5. McGrath, Kris G: 2 articles (11/2019 - 05/2012)
6. Ciprandi, Giorgio: 2 articles (04/2018 - 11/2014)
7. Gelardi, Matteo: 2 articles (04/2018 - 01/2012)
8. Singh, Umesh: 2 articles (01/2017 - 01/2014)
9. Berger, William E: 2 articles (03/2014 - 01/2009)
10. Kriukov, A I: 2 articles (01/2014 - 01/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Vasomotor Rhinitis:
1. azelastine (Optivar)FDA LinkGeneric
2. Nasal SpraysIBA
3. Histamine Antagonists (Antihistamines)IBA
4. Capsaicin (Zostrix)FDA Link
5. Adrenal Cortex Hormones (Corticosteroids)IBA
6. Ipratropium (Ipratropium Bromide)FDA LinkGeneric
7. Budesonide (Pulmicort)FDA LinkGeneric
8. CytokinesIBA
10/01/2003 - "Interestingly, nasal turbinates obtained from patients suffering from nonallergic rhinitis (vasomotor rhinitis) were also found to release eotaxin-2/CCL24 both spontaneously and following cytokine stimulation with IL-4 and IFN-gamma being major inducers of this cytokine. "
01/01/2004 - "While clinical studies of azelastine have demonstrated that this drug is highly efficacious in the treatment of all the symptoms of vasomotor rhinitis, mechanistic studies have demonstrated that azelastine has potent anti-inflammatory effects (in particular attenuation of the expression and synthesis of pro-inflammatory cytokines, leukotrienes, and cell adhesion molecules), which are likely to contribute to its clinical efficacy. "
01/01/2014 - "Our follow-up studies indicated that the nonselective inhibition of cytokine induced pSTAT3 and pSTAT1 activation by G-alpha stimulatory subunit-coupled G-protein-coupled receptor agonists, and forskolin was likely due to cyclic adenosine monophosphate-mediated up-regulation of suppressors of cytokine signaling 3. Azelastine, an H1 receptor antagonist approved for the treatment of seasonal allergic rhinitis, nonallergic vasomotor rhinitis, and ocular conjunctivitis, was subsequently confirmed as a selective inhibitor of IL-6-induced pSTAT3 activation that also reduced the growth of HNSCC cell lines. "
03/01/2003 - "Azelastine has established antiallergic and anti-inflammatory effects that are unrelated to H1-receptor antagonism, including inhibitory effects on the synthesis of leukotrienes, kinins, and cytokines; the generation of superoxide free radicals; and the expression of the intercellular adhesion molecule 1. Azelastine is available in the United States as a nasal spray formulation (Astelin) and is approved for treatment of seasonal allergic rhinitis and nonallergic vasomotor rhinitis. "
9. LeukotrienesIBA
10. GlucocorticoidsIBA

Therapies and Procedures

1. Laser Therapy (Surgery, Laser)
2. Therapeutics
3. Cryotherapy (Therapy, Cold)
4. Nebulizers and Vaporizers (Inhaler)
5. Lasers (Laser)