Rheumatic Fever (Acute Articular Rheumatism)

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1384 relevant articles (30 outcomes, 139 trials/studies) found for this Disease

Description: A febrile disease occurring as a delayed sequela of infections with group A hemolytic streptococci and characterized by multiple focal inflammatory lesions of the connective tissue structures, especially of the heart, blood vessels, and joints (polyarthritis), and by the presence of Aschoff bodies in the myocardium and skin. (Dorland, 27th ed)

Also Known As:

Acute Articular Rheumatism; Arthritis, Acute Rheumatic; Polyarthritis Rheumatica; Rheumatism, Acute Articular; Acute Articular Rheumatisms; Acute Rheumatic Arthritides; Acute Rheumatic Arthritis; Arthritides, Acute Rheumatic; Articular Rheumatism, Acute; Articular Rheumatisms, Acute; Fever, Rheumatic; Fevers, Rheumatic; Polyarthritis Rheumaticas; Rheumatic Arthritides, Acute; Rheumatic Arthritis, Acute; Rheumatic Fevers; Rheumatisms, Acute Articular; Arthritis, Rheumatic, Acute; Rheumatism, Articular, Acute

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Disease Context: Research Results

Bacterial Infections and Mycoses

Bacterial Infections: 6393

Gram-Positive Bacterial Infections: 86

Streptococcal Infections: 872

Rheumatic Fever: 1384

Rheumatic Heart Disease: 573

Musculoskeletal Diseases: 83

Rheumatic Diseases: 4792

Rheumatic Fever: 1384

Rheumatic Nodule: 11

Wissler's Syndrome: 11

Joint Diseases: 1502

Arthritis: 14199

Rheumatic Fever: 1384

Rheumatic Nodule: 11

Wissler's Syndrome: 11

Related Diseases

1.	Infection
2.	Pharyngitis (Sore Throat)
3.	Rheumatic Heart Disease (Rheumatic Heart Diseases)
4.	Myocarditis (Carditis)
5.	Streptococcal Infections (Streptococcal Infection)

Experts

1.	Shulman, Stanford T: 6 articles (01/2008 - 09/2003)
2.	Baltimore, Robert S: 4 articles (01/2008 - 06/2005)
3.	Baddour, Larry M: 4 articles (01/2008 - 06/2005)
4.	Takahashi, Masato: 4 articles (01/2008 - 06/2005)
5.	Ferrieri, Patricia: 4 articles (01/2008 - 06/2005)
6.	Newburger, Jane W: 4 articles (01/2008 - 06/2005)
7.	Taubert, Kathryn A: 4 articles (01/2008 - 06/2005)
8.	Burns, Jane C: 4 articles (01/2008 - 06/2005)
9.	Tani, Lloyd Y: 4 articles (01/2008 - 06/2005)
10.	Levison, Matthew: 3 articles (01/2008 - 06/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Rheumatic Fever:

1.	Penicillins (Penicillin)FDA Link 02/04/1988 - "Penicillin and the marked decrease in morbidity and mortality from rheumatic fever in the United States." 03/01/1987 - "Regular monthly parenteral penicillin was found to be effective in reducing recurrence of rheumatic fever and maintaining good health in these children." 03/01/2003 - "Intramuscular penicillin is more effective than oral penicillin in secondary prevention of rheumatic fever--a systematic review." 12/01/2003 - "CONCLUSIONS: The results of this study suggest that penicillin values may be inadequate for prevention of rheumatic fever by Week 3 of administration in a majority of children." 01/01/2002 - "SELECTION CRITERIA: Randomised and quasi-randomised studies comparing (i) penicillin with control, (ii) oral with intramuscular penicillin (iii) 2- or 3-weekly with 4-weekly intramuscular penicillin in patients with previous rheumatic fever" Order ALL the reference details at left...
2.	Benzathine Penicillin G (LPG)FDA Link 03/01/2000 - "Benzathine penicillin G (BPG) is effective for secondary prophylaxis of rheumatic fever (RF)" 12/01/2004 - "4) Comparative trials done in the 1950s showed that benzathine benzylpenicillin helped prevent acute rheumatic fever, reducing the risk by about 75%" 11/01/1994 - "OBJECTIVE: To compare the efficacy of injections of 1.2 million units of benzathine penicillin G given every 3 weeks versus every 4 weeks for secondary prevention of rheumatic fever, based on the long-term outcome of patients receiving such prophylaxis" 06/01/2001 - "METHODS: Thirty-five children with confirmed rheumatic fever under benzathine penicillin prophylaxis were enrolled in the study and 35 healthy children with similar ages and socioeconomic backgrounds served as controls" 02/01/2001 - "Thirty children with confirmed rheumatic fever who were on the benzathine penicillin prophylaxis were enrolled in the study, and 30 similar normal children served as a control group" Order ALL the reference details at left...
3.	Anti-Bacterial Agents (Antibiotics)IBA 01/01/2006 - "Several studies found antibiotics reduced acute rheumatic fever by more than two thirds (relative risk (RR) 0.22; 95% CI 0.02 to 2.08)" 01/01/2004 - "Several studies found that antibiotics reduced acute rheumatic fever, to less than one third (odds ratio (OR) = 0.30; 95% confidence interval (CI) = 0.20 to 0.45)" 01/01/2000 - "Several studies found benefit from antibiotics for acute rheumatic fever, which reduced this complication to less than one third (OR = 0.30; 95% CI = 0.20-0.45)" 01/01/2000 - "Several studies found benefit from antibiotics for acute rheumatic fever, which reduced this complication to less than one third (OR = 0.30; 95% CI = 0.20-0.45)" 01/01/1985 - "A multi-centre study conducted by the WHO has shown that the cost of antibiotics used for secondary prevention was less than the savings resulting from the lower incidence and shorter hospital stays of recurrencies of rheumatic fever" Order ALL the reference details at left...
4.	AntigensIBA 07/15/2003 - "BACKGROUND: Rheumatic fever has become uncommon in the United States while rapid diagnostic test technology for streptococcal antigens has improved" 10/01/1992 - "We report the results of research on human leukocyte allo-antigen (HLA) and rheumatic fever (RF), the first published study to be carried out among Turkish children with RF" 09/01/1990 - "Immunogenetic study of the response to streptococcal carbohydrate antigen of the cell wall in rheumatic fever." 07/01/1989 - "Our study examines the distribution of cells bearing these "rheumatic" antigens in 23 subjects with rheumatic fever/RHD of Maori, Polynesian and Caucasian ancestry and 182 members of their families (rheumatic fever/RHD families) as well as in 46 members of families in which no member had been demonstrated to have had rheumatic fever/RHD (control families)" 10/01/1988 - "This assumption needs a detailed study in view of the hypothesis about the important role of cross-reactive antigens of group A streptococci in generating autoimmune process during rheumatic fever and other streptococcal diseases" Order ALL the reference details at left...
5.	AntibodiesIBA 12/01/1985 - "A study of four anti-streptococcal antibodies in rheumatic fever and diseases related with streptococci in childhood]" 03/01/1980 - "This study was made to evaluate the value of the IHA test for streptococcal antibodies in children with acute rheumatic fever in comparison with the conventional ASO titer" 01/01/1975 - "Studies of heart reactive antibodies in rheumatic fever]" 12/01/1965 - "Studies of the antibodies reacting with human heart muscle in rheumatic fever of the child." 01/01/2004 - "In rheumatic fever, antibodies generated against GABHS cross-react with the heart, joints, skin, and other sites, inducing an inflammatory, multisystem disease" Order ALL the reference details at left...
6.	Antistreptolysin (Antistreptolysin O)IBA 05/01/1957 - "Further studies on rheumatic fever epidemiology; comparative incidence of rheumatic fever, streptococcal carriers, and antistreptolysin titers in the tropics and in Mexico City." 03/01/2005 - "OBJECTIVES: To determine the relationship between the severity of clinical features of rheumatic fever (RF), and antistreptolysin O titre (ASOT) and/or erythrocyte sedimentation rate (ESR)" 10/01/1995 - "He met the Jones criteria for the diagnosis of acute rheumatic fever and had an increased result for antistreptolysin O antibody titer" 12/01/1976 - "The prolonged rise in antistreptolysin 0 titer which might suggest rheumatic fever, was not explained, but as the streptococcus was never found in throat swabs, it is probable that this was a non-specific phenomenon" 11/24/1975 - "Prevention of recurrences of rheumatic fever and significance of the behavior of the antistreptolysin titer]" Order ALL the reference details at left...
7.	Immunoglobulins (Immunoglobulin)IBA 01/23/2001 - "Intravenous immunoglobulin in acute rheumatic fever: a randomized controlled trial." 07/01/1972 - "Immunological remarks on rheumatic fever in children with reference to heart-reactive serum factors, immunoglobulins and 1C -globulin levels." 07/01/1968 - "Immunoglobulins in rheumatic fever." 09/01/1967 - "The immunoglobulins in rheumatic fever in childhood]" 02/01/1987 - "Serum levels of immunoglobulins in acute rheumatic fever and rheumatic heart disease." Order ALL the reference details at left...
8.	SteroidsIBA 07/01/1976 - "Since the patients with rheumatic fever usually receive anti-inflammatory treatment with steroids, and as these drugs are capable of decreasing selectively the "T" lymphocytes, their effect on the kinetics of the lymphocytes in rheumatic fever has to be elavuated in further studies." 07/01/2002 - "Acute rheumatic fever: whither steroids?" 01/01/1983 - "Effect of anabolic steroids on indices of the blood coagulation system and fibrinolysis during protracted rheumatic fever with stage IIA circulatory insufficiency]" 09/01/1967 - "Treatment with steroids of 204 acute cases of rheumatic fever]" 09/01/1964 - "SHORT-ACTING STEROIDS IN THE TREATMENT OF RHEUMATIC FEVER.]" Order ALL the reference details at left...
9.	Immunoglobulin A (IgA)IBA 01/01/1987 - "A combination of two variables (artificial subcutaneous nodules and IgA) had a sensitivity of 84% and a specificity of 100% for rheumatic fever." 01/01/1987 - "A combination of three variables (artificial subcutaneous nodules, IgA, and C3) had a sensitivity of 87% and a specificity of 100% for rheumatic fever" 07/01/1982 - "However, its presence in rheumatic fever patients did not correlate directly with amounts of serum IgA present (r = 0.0507)" 01/31/1981 - "Quantitative changes of IgA in rheumatic fever" 07/01/1982 - "Serum immunoglobulin A and antibody to M-associated protein in patients with acute glomerulonephritis or rheumatic fever." Order ALL the reference details at left...
10.	Anticardiolipin AntibodiesIBA 08/01/1992 - "Anticardiolipin antibodies in acute rheumatic fever." 08/01/1992 - "We conducted a case series and a case-control investigation of patients with rheumatic fever with Sydenham chorea or other manifestations of rheumatic fever for anticardiolipin antibodies (aCL) during the acute attack and disease remission" 09/01/1996 - "Anticardiolipin antibodies in acute rheumatic fever and chronic rheumatic heart disease: is there a significant association?" 12/01/1994 - "Anticardiolipin antibodies, rheumatic fever and rheumatic heart disease." 01/01/2001 - "Serum samples of 31 consecutive patients with rheumatic heart disease and documented valve involvement, as well as six patients with acute rheumatic fever were tested for IgG anticardiolipin antibodies by a validated ELISA" Order ALL the reference details at left...

Therapies and Procedures

1.	Chemoprevention 07/01/1998 - "This study confirms that recurrence of rheumatic fever in patients with RHD above 26 years of age is very low and hence we recommend long term chemoprophylaxis to the patients above the age of 26 on an individual basis." 01/26/1956 - "Studies of bacterial throat flora during chemoprophylaxis of rheumatic fever." 07/01/1998 - "Rheumatic fever chemoprophylaxis in adults." 01/01/1966 - "Chemoprevention of rheumatic fever." 10/10/1965 - "Chemoprophylaxis of relapse of rheumatic fever]" Order ALL the reference details at left...
2.	Baths 01/01/1984 - "The paper discusses the efficacy of rehabilitation of 108 patients with rheumatic fever with the use of radon baths, of them in 36 in conjunction with homologous immunoglobulin" Order ALL the reference details at left...
3.	Nursing Care 03/30/1978 - "Nursing care study: rheumatic fever." 07/01/1977 - "Nursing care study (rheumatic fever)." 01/01/1949 - "Nursing care study on acute and convalescent rheumatic fever." 01/01/1978 - "Chosen example: nursing care in rheumatic fever]" 06/01/1952 - "The nursing care of children with acute rheumatic fever." Order ALL the reference details at left...
4.	Tonsillectomy 06/01/1990 - "No association between the disease and antecedents of tonsillectomy, rheumatic fever, educational level, place of residence, or marital status was found." 04/04/1970 - "Tonsillectomy after rheumatic fever." 12/16/1967 - "Tonsillectomy and rheumatic fever." 04/01/1967 - "Effect of tonsillectomy on the frequency of recurrences of rheumatic fever]" 03/01/1966 - "Slow" or "rapid" tonsillectomy in rheumatic fever of tonsillar origin, in childhood?]" Order ALL the reference details at left...
5.	Bed Rest (Bedrest) 07/27/1957 - "Role of bed rest in treatment of rheumatic fever; review of literature and survey of current opinions." 11/01/1949 - "Bed rest; a program for rheumatic fever patients." 09/01/1959 - "Relation of duration of bed rest in acute rheumatic fever to heart disease present 2 to 14 years later." 09/01/2001 - "Studies from the rheumatic fever research unit at Taplow showed absence of cardiac dilatation in first attacks of rheumatic carditis, poor prognosis with pericardial effusions, changing murmurs recorded by phonocardiography and cardiac output studies that justified treatment by bed rest" 06/10/1961 - "Five-year follow-up on patients with rheumatic fever treated by bed rest, steroids, or salicylate." Order ALL the reference details at left...

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