Rhenium

01/01/2019 - "The present review focused on the rhenium based cancer drugs that were in preclinical and clinical trials were examined critically. "
03/17/2023 - "Rhenium (Re) is widely used in the diagnosis and treatment of cancer due to its unique physical and chemical properties. "
07/06/2022 - "This is attributed the amazing photophysical properties of rhenium complexes together with their ability to selectively attack different organelles in cancer cells. "
03/01/2022 - "Rhenium compounds have shown anti-cancer properties against many different types of cancer cell lines; however, the cellular signaling mechanisms involved in the cytotoxic properties of rhenium-based compounds were never deciphered or reported. "
12/07/2020 - "We describe rhenium complexes which block cancer proliferation in vitro by inhibiting the signalling cascade induced by FGFR and Src. "

02/01/2015 - "To study the efficacy of novel rhenium compounds to treat triple node negative breast cancer. "
05/01/2001 - "This study suggests that technetium-99m rhenium sulphide is a suitable agent for sentinel node mapping in patients with breast cancer."
01/01/2020 - "Evaluation of the diester anticancer activity against breast cancer cell line (MCF-7) showed high percent of inhibition about 61.5% at 100 μg/ml. The rhenium complex of the diester was synthesized and characterized by liquid chromatography-mass spectrometry (ESI) and elemental analysis depending on the strong chemical resemblance between Tc and Re. "
01/01/2020 - "We recorded spectra of single, living, fully hydrated breast cancer MDA-MB231 cells and could follow the penetration of the rhenium complexes for up to 2 h. "
11/01/2016 - "Dose Effect of Rhenium (I)-diselenoether as Anticancer Drug in Resistant Breast Tumor-bearing Mice After Repeated Administrations."

10/01/1993 - "A phase I trial of a rhenium 186-labeled monoclonal antibody administered intraperitoneally in ovarian carcinoma: toxicity and clinical response."
01/01/2015 - "[Antioxidant properties of cluster rhenium compounds and their effect on erythropoiesis of rats with guerin carcinoma]."
06/01/1987 - "The SPECT images and the distribution of accumulation of Tc-99m Rhenium colloid into the regional lymph nodes indicated a similar tendency to the actual metastatic rate of carcinoma of the cardia. "
10/01/1993 - "Rhenium 186 was conjugated to murine monoclonal antibody NR-LU-10, which binds to a cell surface antigen present on ovarian carcinoma. "
09/12/2023 - "An emerging therapeutic approach with high-dose brachytherapy using a nonsealed rhenium-188 resin, commercially known as Rhenium-Skin Cancer Therapy®, has been shown to be highly effective in non-invasive carcinoma, up to a thickness of 2-3 mm."

04/01/1999 - "The aim of this study was to fully characterize newly developed radioactive rhenium glass microspheres in vivo by determining their biodistribution, stability, antitumor effect, and toxicity after hepatic arterial injection in a syngeneic rat hepatoma model. "
04/01/1999 - "Rhenium glass microspheres were made radioactive by neutron activation and then injected into the hepatic artery of Sprague-Dawley rats containing 1-week-old Novikoff hepatomas. "
09/01/2013 - "In vitro demonstration of synergy/additivity between (188)rhenium and sorafenib on hepatoma lines: preliminary results."
01/01/2006 - "Management of postsurgical recurrence of hepatocellular carcinoma with rhenium 188-HDD labeled iodized oil."
05/01/2007 - "To prospectively evaluate, in a multicenter clinical trial, dosimetry-guided transarterial radionuclide therapy (TART) with rhenium 188 ((188)Re) 4-hexadecyl 1,2,9,9-tetramethyl-4,7-diaza-1,10-decanethiol (HDD)-labeled iodized oil in inoperable hepatocellular carcinoma (HCC). "

07/01/2023 - "A novel tool for predicting the dose distribution of non-sealed 188 Re (Rhenium) resin in non-melanoma skin cancers (NMSC) patients."
07/01/2023 - "High-dose rate brachytherapy using a non-sealed 188 Rhenium resin (188 Re) is a recently approved treatment option for non-melanoma skin cancer (NMSC). "
05/01/2021 - "Correction to: High dose brachytherapy with non sealed 188Re (rhenium) resin in patients with non-melanoma skin cancers (NMSCs): single center preliminary results."
01/01/2021 - "High dose brachytherapy using a non sealed 188Re-resin (Rhenium-SCT®, Oncobeta® GmbH, Munich, Germany) is a treatment option for non-melanoma skin cancer (NMSC). "
01/01/2021 - "High dose brachytherapy with non sealed 188Re (rhenium) resin in patients with non-melanoma skin cancers (NMSCs): single center preliminary results."