Respiratory Hypersensitivity

1.	Pauluhn, Jürgen: 3 articles (12/2003 - 02/2002)
2.	Eidmann, Petra: 2 articles (03/2002 - 02/2002)
3.	Pauluhn, J: 1 article (09/2002)
4.	Ahr, H J: 1 article (09/2002)
5.	Vohr, H-W: 1 article (09/2002)
6.	Wasinska-Kempka, Grazyna: 1 article (03/2002)
7.	Vohr, Hans-Werner: 1 article (03/2002)
8.	Freyberger, Alexius: 1 article (03/2002)
9.	Mohr, Ulrich: 1 article (02/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Respiratory Hypersensitivity:

1.	Immunoglobulin E (IgE)IBA 05/01/2000 - "Despite the controversy regarding an obligatory role for IgE, there is a growing consensus that chemical respiratory hypersensitivity is associated with the selective development of T lymphocytes with a type 2 (Th2) phenotype. " 11/01/1998 - "The mechanism of respiratory hypersensitivity is still unknown, and it is probably not IgE-mediated." 05/01/1984 - "[Correlation between total IgE, blood and secretory eosinophils, bronchial reactivity and skin tests in respiratory hypersensitivity in the adult]" 05/01/2006 - "The following working definition of respiratory hypersensitivity was formulated: a hypersensitivity response in the respiratory tract precipitated by a specific immune response, mediated by multiple mechanisms, including IgE antibody. " 01/03/2001 - "A respiratory hypersensitivity caused by TMA, but not by DNCB, may be partly due to the presence of immuno effector cells bearing IgE at their surface in airway microenvironments, and their presence might be related to the higher level of serum total IgE. " Order ALL the reference details at left...
2.	AllergensIBA 06/01/1995 - "A murine model for assessing the respiratory hypersensitivity potential of chemical allergens." 12/01/1992 - "Conversely, chemical allergens which are known to cause respiratory hypersensitivity stimulate preferentially TH2-type responses. " 11/01/2000 - "The evidence reveals that individuals with allergic rhinitis are sensitized to the eliciting allergens and exhibit cutaneous and respiratory hypersensitivity responses on exposure to the allergen. " 08/01/1996 - "Allergy and respiratory hypersensitivity are the end results of an interaction in genetically susceptible individuals, exposure to allergens and adjuvant factors. " 08/01/1994 - "This paper describes clinical syndromes, mechanisms associated with occupational respiratory hypersensitivity, and methods available currently for the prospective identification of potential respiratory allergens. " Order ALL the reference details at left...
3.	Toluene 2,4-Diisocyanate (Toluene Diisocyanate)IBA 12/01/1997 - "Assessment of respiratory hypersensitivity in guinea pigs sensitized to toluene diisocyanate: improvements on analysis of respiratory response." 06/01/1993 - "In this study, we demonstrate the influences of the toluene diisocyanate (TDI) treatment on the histamine content and these enzyme activities in guinea-pigs as an animal model of respiratory hypersensitivity. " 06/01/1995 - "Using equimolar quantities of 2 chemical allergens, toluene diisocyanate (TDI), noted for its ability to cause respiratory hypersensitivity, and dinitrochlorobenzene (DNCB), noted for its dermal sensitizing activity, the mouse was evaluated as a possible model to indicate respiratory hypersensitivity. " Order ALL the reference details at left...
4.	IsocyanatesIBA 11/01/2006 - "Based on the weight of evidence from all the assays performed, it appears that all six isocyanates tested have some potential to cause respiratory hypersensitivity following dermal exposure." 11/01/2007 - "The purpose of this study was to determine if the cytokine profile induced after dermal sensitization with isocyanates and serum IgE predict immediate (IHS) and methacholine-induced late (LHS) respiratory hypersensitivity responses after intranasal challenge. " Order ALL the reference details at left...
5.	Methacholine Chloride (Methacholine)FDA Link 11/01/2007 - "The purpose of this study was to determine if the cytokine profile induced after dermal sensitization with isocyanates and serum IgE predict immediate (IHS) and methacholine-induced late (LHS) respiratory hypersensitivity responses after intranasal challenge. " Order ALL the reference details at left...
6.	VenomsIBA 04/01/2003 - "METHODS: This study analysed the administration of specific immunotherapy during a period of 5 years, involving 1212 patients affected by respiratory hypersensitivity or hymenoptera venom anaphylaxis. " Order ALL the reference details at left...
7.	Histamine (Histamine Dihydrochloride)IBA 06/01/1993 - "These data suggest that the turnover rate of histamine is increased in the nasal mucosa and the lung of guinea pigs with respiratory hypersensitivity." 06/01/1993 - "In this study, we demonstrate the influences of the toluene diisocyanate (TDI) treatment on the histamine content and these enzyme activities in guinea-pigs as an animal model of respiratory hypersensitivity. " Order ALL the reference details at left...
8.	EnzymesIBA 04/01/1983 - "These studies suggest that, although repeated inhalation of purified chymotrypsin may induce respiratory hypersensitivity in horses, the chymotrypsin-like enzymes of M. " Order ALL the reference details at left...
9.	Chymotrypsin FDA Link 04/01/1983 - "These studies suggest that, although repeated inhalation of purified chymotrypsin may induce respiratory hypersensitivity in horses, the chymotrypsin-like enzymes of M. " Order ALL the reference details at left...
10.	AcrylatesIBA 11/01/1998 - "OBJECTIVE: The aim of the present study was to report the cases of acrylates induced respiratory hypersensitivity in dental personnel diagnosed in Finland during the last 6 years. " 11/01/1998 - "RESULTS: Twelve cases of respiratory hypersensitivity caused by acrylates diagnosed in dental personnel (six dentists and six dental nurses) in 1992-97 are reported. " 11/01/1998 - "Occupational respiratory hypersensitivity caused by preparations containing acrylates in dental personnel." Order ALL the reference details at left...

Therapies and Procedures

1.	Immunotherapy 04/01/2003 - "METHODS: This study analysed the administration of specific immunotherapy during a period of 5 years, involving 1212 patients affected by respiratory hypersensitivity or hymenoptera venom anaphylaxis. " Order ALL the reference details at left...
2.	Intraperitoneal Injections 01/01/1977 - "The feline model of respiratory hypersensitivity induced by intraperitoneal injection of ovalbumin has been studied. " Order ALL the reference details at left...
3.	Intravenous Infusions 01/01/1976 - "Respiratory hypersensitivity and systemic effects after local application of Ascaris suum extract on the segmental bronchus and after its intravenous infusion are studied on four boxer dogs. " Order ALL the reference details at left...

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